Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$223K - $313K *

Elevate healthcare outcomes by leading clinical determinations and authorizations. Utilize your medical expertise to ensure compliance with national guidelines while collaborating with diverse teams i...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $110K *

Drive your career forward as you lead daily operations at a new clinical research site, ensuring participant safety and high-quality data while achieving financial and enrollment goals in a collaborat...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Drive clinical research excellence by overseeing site operations, ensuring participant safety, and achieving financial and enrollment goals. Lead a dedicated team to deliver high-quality data while ad...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Advance high-quality resident care and regulatory excellence in Assisted Living. Collaborate with clinical and operational teams to enhance services, mentor leaders, and drive performance improvement...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$85K - $100K *

Lead clinical excellence across Assisted Living communities, driving quality care, regulatory compliance, and performance improvement while mentoring future clinical leaders and enhancing resident exp...

2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$140K - $200K *

Drive the execution of innovative clinical trials in a fast-paced biotech environment, ensuring compliance and effective collaboration with teams to meet study objectives and timelines across diverse...

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$244K - $305K *

Lead the charge in building and optimizing regulatory information management capabilities, focusing on Veeva Vault RIM. Collaborate across functions to enhance global processes and ensure compliance w...

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Take ownership of operational oversight for surgical services across multiple practices, ensuring compliance, quality improvement, and engagement while managing a diverse team for optimal performance...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$124K - $146K *

Join a dedicated team as a Clinical Director, overseeing daily operations, enhancing patient care, and implementing process improvements in a fast-paced outpatient endoscopy center. Collaborate with l...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$125K - $156K *

Drive operational excellence in a fast-paced ASC environment, enhancing patient care and staff performance while ensuring compliance and fiscal accountability. Collaborate with leadership to implement...

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Join a team that's dedicated to enhancing patient care and operational efficiency. As a Clinical Director, you'll oversee daily operations, implement process improvements, and lead a skilled team to a...

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Innovate your career by leading clinical operations in a dynamic outpatient surgery center. Drive efficiency, enhance patient care, and oversee staff development while ensuring compliance with industr...

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$116K - $132K *

Lead the charge in enhancing patient care as a Registered Nurse Clinical Director, overseeing operations, staff performance, and compliance in a dynamic surgical environment while driving initiatives...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$116K - $146K *

Lead the clinical operations of the surgery center, enhancing patient care and staff performance through strategic planning, compliance monitoring, and effective resource management to ensure optimal...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$297K - $360K *

Oversee strategic initiatives within the Protocol Management Office to enhance clinical development quality, ensuring scientific rigor in clinical protocols and compliance while driving innovation and...

1 month ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$297K - $360K *

Advance clinical excellence by leading the Protocol Management Office, ensuring rigorous scientific review of key documents while enhancing education and innovation in clinical development across ther...

1 month ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Drive the development and oversight of clinical departments in an ambulatory surgical center, focusing on staff management, quality assurance, and strategic growth to ensure operational excellence and...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Lead the charge in enhancing clinical operations and patient care in an ambulatory surgical setting. Oversee staff performance, implement process improvements, and ensure compliance with safety measur...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$175K - $210K *

Drive quality excellence in clinical programs by overseeing compliance, risk management, and vendor oversight. Collaborate cross-functionally to ensure adherence to GCP regulations and lead inspection...

San Francisco, CARemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$175K - $210K *

Drive quality oversight for clinical studies, ensuring compliance and risk management. Collaborate with cross-functional teams to implement quality strategies and serve as a trusted advisor, enhancing...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$195K - $240K *

Shape the future of strategic initiatives by leading cross-functional teams to drive impactful projects in North America. Collaborate with senior leadership to align strategies, evaluate progress, and...

Reposted 3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Innovate laboratory operations by leading a team to enhance efficiency, compliance, and strategic alignment. Oversee budget management, quality initiatives, and technological advancements to support c...

2 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$110K - $125K *

Oversee clinical operations and lead interdisciplinary teams to enhance patient recovery through evidence-based practices and individualized care in a dynamic behavioral health setting...

Today

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$90K - $95K *

Manage and oversee clinical support teams, ensuring adherence to policies, optimizing training outcomes, and maintaining high-quality client care while fostering effective communication across departm...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$135K - $170K *

Join a team that's driving innovative clinical research across multiple regions, leading teams to ensure on-time deliverables and high-quality data management in complex trials. Support site managemen...

Reposted 2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.