Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$160K - $180K *

Drive operational excellence and customer experience leadership, shaping strategies and systems for growth. Collaborate with executives to enhance efficiency and lead a dedicated team, ensuring seamle...

Toronto, ONIn-Person

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $160K *

Accelerate progress at the forefront of clinical supply integration. Lead coordination efforts across global teams, ensuring timely delivery of investigational products while driving continuous improv...

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $160K *

Deliver excellence in clinical supply integration by coordinating global operations, managing timelines, and ensuring effective collaboration across teams and vendors. Lead initiatives to optimize pro...

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$173K - $272K *

Lead a talented team of scientists to drive analytical excellence in large molecule programs, ensuring compliance and operational efficiency while fostering talent development and strategic partnershi...

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$173K - $272K *

Join us to lead a talented team of scientists in advancing large molecule programs, driving operational excellence, and fostering strategic partnerships to enhance clinical supply and commercializatio...

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$177K - $278K *

Transform trial performance through strategic insights and data governance, enhancing decision-making and accelerating delivery. Lead cross-functional partnerships to drive measurable improvements in...

2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$164K - $205K *

Manage end-to-end biomarker operations for Phase I-III oncology trials. Collaborate with cross-functional teams to ensure successful execution of clinical strategies, vendor management, and adherence...

2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$157K - $205K *

Join a team that's driving innovation in clinical analytics and consulting. Lead business development and client engagement for pharmaceutical and biotech clients, leveraging advanced analytics and AI...

3 weeks ago

  •   11 - 15 years exp.  •   Business Services

$110K - $130K *

Drive client success by leading a dedicated team, developing strategies to enhance satisfaction, retention, and growth. Foster client relationships and implement initiatives that align with client obj...

1 month ago

  •   8 - 10 years exp.  •   Healthcare

$180K - $220K *

Join a team that's driving innovative oncology solutions while overseeing clinical trials, ensuring patient safety, and collaborating with cross-functional teams to contribute to impactful drug develo...

United StatesRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$190K - $260K *

Transform client delivery in biotech by leading a high-performing team, driving operational excellence, and fostering innovation. Champion technology adoption and continuous improvement to enhance cli...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$240K - $328K *

Unlock potential by leading HEOR strategies to demonstrate the healthcare value of products. Collaborate with cross-functional teams to create evidence for informed decision-making, while managing pro...

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$161K - $175K *

Champion biomarker and biospecimen operations, ensuring compliance and quality throughout clinical trials. Lead vendor management and collaborate with cross-functional teams to drive efficiency and op...

4 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$138K - $238K *

Partner with us to lead operational excellence in Payment Integrity, driving strategic initiatives and cross-functional collaboration. Utilize data insights to enhance performance, manage inventory, a...

1 week ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$138K - $238K *

Drive operational excellence as you lead key functions in Payment Integrity Operations. Collaborate with cross-functional teams to enhance processes, manage inventory, and support strategic initiative...

1 week ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$138K - $238K *

Elevate operational excellence by leading Payment Integrity initiatives, driving strategic alignment, and enhancing workforce effectiveness through data-driven insights and cross-functional collaborat...

1 week ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$138K - $238K *

Shape the future of financial operations by leading Payment Integrity initiatives, driving process excellence, and enhancing operational efficiency. Collaborate with cross-functional teams to align st...

1 week ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$138K - $238K *

Lead the charge in optimizing financial operations and payment integrity. Drive strategic initiatives, enhance process excellence, and collaborate across teams to ensure operational alignment and effe...

1 week ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$92K - $124K *

Transform clinical operations by leading staff training, scheduling, and program development. Collaborate with teams to ensure high-quality patient care and compliance, fostering a supportive environm...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$225K - $281K *

Join a team that's pushing the boundaries of oncology research! This key role involves designing and leading clinical trials, ensuring data integrity, and collaborating with global experts to advance...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$225K - $281K *

Explore your career in clinical development as you design and lead innovative oncology studies, ensuring data integrity and compliance while collaborating with cross-functional teams and cultivating r...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$114K - $219K *

Transform operational and financial performance across multiple clinical offices. Lead and mentor Office Managers to ensure efficient patient care delivery while developing marketing strategies and op...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$255K - $294K *

Elevate your career by leading Medical Affairs, Clinical Operations, and Regulatory Affairs. Drive strategic initiatives, foster cross-functional collaboration, and ensure compliance in a dynamic envi...

Yesterday

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$135K - $165K *

Lead the transformation of clinical production processes, optimizing workflows for medical imaging analysts. Collaborate across teams to enhance operational efficiency and ensure compliance in an FDA...

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$130K - $188K *

Transform clinical operations by leading staff, developing strategies, and ensuring evidence-based, culturally safe patient care within a diverse health care environment. Engage collaboratively to enh...

Nanaimo, BCIn-Person

Reposted 1 week ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.