Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$100K - $120K *

Partner with us to enhance clinical training across multiple centers, ensuring high standards of care and effective program delivery. Lead initiatives to evaluate and improve training effectiveness wh...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Help us drive excellence in clinical training across our regional centers. You'll oversee training programs, evaluate clinical care quality, and collaborate with leaders to ensure compliance with best...

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$70K - $100K *

Lead transformative mental health services by overseeing clinical operations, ensuring compliance, and fostering a supportive environment for both staff and clients. Drive program success through effe...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Shape the future of inpatient nursing operations by providing strategic leadership and ensuring high-quality, patient-centered care across diverse clinical settings. Collaborate with interdisciplinary...

Today

  •   5 - 7 years exp.  •   Healthcare

$230K - $245K *

Empower your career by leading cross-functional teams in drug development. Drive execution, foster collaboration, and ensure alignment on strategic objectives while navigating a fast-paced environment...

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Oversee nursing operations across multiple facilities, ensuring compliance, quality assurance, and effective interdisciplinary collaboration. Lead initiatives in patient safety, staffing, and regulato...

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Transform operations by overseeing daily functions, ensuring safety, managing budgets, and enhancing customer satisfaction. Lead a team to drive profitability and operational efficiency while fosterin...

1 week ago

  •   8 - 10 years exp.  •   Telecommunications & Hardware

$70K - $125K *

Drive seamless creative delivery for digital media campaigns, ensuring timely and quality asset execution. Collaborate with diverse teams to optimize workflows and enhance communication, making a sign...

4 days ago

  •   5 - 7 years exp.  •   Media

$176K - $220K *

Drive operational excellence and regulatory integration for translational biology programs. Collaborate across functions to ensure compliance and execution readiness, while managing risks and fosterin...

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Join a team that's dedicated to delivering high-quality patient care while leading the medical-surgical department. Drive operational excellence, foster collaboration, and ensure compliance with healt...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$150K - $175K *

Lead a dynamic team to drive excellence in clinical trial design and execution, ensuring compliance with regulations and collaboration with cross-functional partners to enhance clinical strategy and o...

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $175K *

Join a dynamic team to oversee clinical trials, ensuring excellence in design and execution. Provide strategic leadership and manage resources across projects to uphold regulatory compliance while fos...

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$180K - $220K *

Transform patient care by leading medical initiatives and coordinating treatment plans to promote the highest quality of health in residents. Collaborate with healthcare teams to enhance nursing progr...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Advance clinical excellence by providing leadership and oversight in skilled nursing and long-term care facilities, ensuring high-quality, patient-centered care through collaboration with interdiscipl...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$160K - $190K *

Lead strategic operations and analytics within Global Medical Affairs, ensuring excellence in project execution and data-driven insights. Collaborate cross-functionally to align initiatives with corpo...

6 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$160K - $190K *

Transform Global Medical Affairs by leading operations and analytics, ensuring strategic alignment and data-driven decisions. Drive excellence across teams, manage budgets, and foster collaboration to...

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$210K - $250K *

Transform patient care by leading and coaching Primary Care providers while ensuring clinical excellence and operational efficiency in a collaborative environment that integrates behavioral health ser...

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$160K - $200K *

Drive innovation by leading integration engineering for healthcare AI, ensuring seamless EHR connectivity and operational excellence. Collaborate across teams to enhance patient engagement tools and m...

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$154K - $431K *

Elevate your career by providing expert medical guidance in dermatology, supporting clinical trials and project delivery. Collaborate with teams to ensure patient safety and protocol adherence while e...

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Join us in leading the development and execution of comprehensive risk management strategies. Collaborate with executive leadership to identify and mitigate enterprise risks, ensuring organizational r...

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$150K - $180K *

Lead the charge in developing and implementing risk management strategies to identify, assess, and mitigate enterprise risks, ensuring alignment with organizational goals and compliance requirements w...

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$144K - $160K *

Champion operational excellence by leading teams to enhance efficiency and care delivery. Drive AI integration, manage P&L, and collaborate cross-functionally to support growth and sustainability in h...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$115K - $198K *

Join us to lead innovative clinical programs, enhancing care solutions across oncology and cardiovascular disease. Collaborate with stakeholders to improve member experiences and clinical outcomes whi...

2 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$115K - $198K *

Join a team that's dedicated to enhancing clinical programs across oncology and cardiovascular care. Lead initiatives that improve member experiences and outcomes while collaborating with key stakehol...

2 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$115K - $198K *

Join a dynamic team as you lead innovative clinical programs, enhancing care solutions across oncology and cardiovascular disease. Collaborate with stakeholders to improve member experiences and clini...

2 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.