Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$110K - $130K *

Unlock potential by leading integration efforts in healthcare technology. Collaborate with cross-functional teams to enhance clinical workflows and ensure seamless data exchange, while maintaining hig...

Chicago, ILRemote

3 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$125K - $150K *

Unlock operational excellence as you lead cross-functional teams in driving technical standardization and scalable training frameworks across Data Centers and Warehouses, ensuring compliance and maxim...

Texas, USRemote

Yesterday

  •   5 - 7 years exp.  •   Transportation

$93K - $140K *

Lead the charge in managing case management programs, ensuring alignment with industry standards and company goals. Oversee departmental operations, drive innovation, and foster collaboration to enhan...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Transform enterprise resilience by leading strategic initiatives in crisis management, business continuity, and disaster recovery. Collaborate across functions to enhance operational readiness and ens...

Minneapolis, MNRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$135K - $160K *

Lead the charge in engineering excellence by managing complex projects, mentoring teams, and driving innovative technology implementations. Ensure sustainable operations while aligning with business o...

Georgia, USRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Transportation

$88K - $105K *

Champion compliance initiatives by developing programs and training materials, ensuring adherence to regulations across UPMC. Collaborate with various departments to mitigate risks and enhance ethical...

Pittsburgh, PARemote

Today

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$232K - $348K *

Elevate customer understanding by leading analytics teams to deliver actionable insights that drive strategic decisions and enhance customer experiences across diverse markets and stakeholders...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$102K - $133K *

Unlock potential by optimizing clinical systems and driving informatics initiatives. This role combines strategy with hands-on support across EHR applications, fostering collaboration to enhance workf...

RemoteRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $115K *

Transform your career by leading financial strategy and operations for innovative service lines. Collaborate with senior leaders to enhance profitability, oversee budgeting, and drive growth initiativ...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$73K - $110K *

Drive innovation by collaborating with users to enhance Electronic Medical Record and Financial Applications. You'll design, build, and integrate solutions while ensuring compliance and patient safety...

Grand Forks, NDRemote

Reposted today

  •   Less than 5 years exp.  •   Healthcare

$160K - $200K *

Join a dynamic team to drive employer strategy and cultivate relationships with corporate benefits executives, enhancing the adoption of innovative Virtual Care solutions in a complex sales environmen...

Minneapolis, MNRemote

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $100K *

Join a team that's passionate about transforming complex scientific data into engaging communications. Collaborate with cross-functional experts to deliver high-quality medical content and strategies...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$145K - $195K *

Unlock patient engagement strategies by integrating insights into drug development. Collaborate with diverse teams to generate evidence, engage with professional societies, and lead initiatives that p...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $200K *

Drive regional sales success by leading a team focused on MRD testing. Oversee business plans, manage account executives, and cultivate key relationships to achieve sales objectives across multiple st...

Illinois, USRemote

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$184K - $254K *

Shape the future of corporate strategy by leading cross-functional teams to develop enterprise-wide strategic plans, drive growth initiatives, and influence senior leadership decisions through data-dr...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Accelerate progress at the forefront of litigation support services. Join a dynamic team dedicated to client success, driving sales strategies, and enhancing customer satisfaction while achieving pers...

San Francisco, CARemote

5 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$110K - $130K *

Unlock potential by becoming a trusted advisor in litigation support services, driving sales growth through client engagement, strategic partnerships, and expert knowledge in Electronic Data Discovery...

Seattle, WARemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$210K - $255K *

Shape the future of cancer treatment by leading Field Medical Excellence initiatives. Drive operational improvements, strategic planning, and cross-functional collaboration to enhance the impact of ou...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$163K - $214K *

Lead the charge in defining strategic market presence and network design. Drive investment decisions by analyzing demand, competition, and demographics to optimize facility configurations across multi...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Technical Services

$110K - $135K *

Create strategic account plans and drive revenue growth by leading expansion discussions and managing a diverse portfolio of commercial accounts, ensuring alignment and collaboration with cross-functi...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Media

$100K - $300K *

Unlock potential by driving enterprise growth in non-commercial foodservice technology. Own the full sales lifecycle, engage stakeholders, and deliver tailored solutions that enhance operational effic...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$150K - $180K *

Elevate sales performance by developing and scaling a forward-thinking sales enablement strategy. Lead onboarding, ongoing skills enhancement, and sales methodology adherence while leveraging AI-drive...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$145K - $155K *

Elevate nursing standards by developing and monitoring clinical programs, ensuring compliance with regulations, and providing training to enhance facility operations and staff performance across multi...

Oregon, USRemote

Today

  •   15+ years exp.  •   Business Services

$130K - $216K *

Join a dynamic team to lead technology consulting projects in biopharma, ensuring successful implementation of patient services solutions. Collaborate with clients and cross-functional teams to drive...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Business Services

$155K - $185K *

Drive the development of a scalable care delivery platform, enhancing clinical workflows and provider tools. Collaborate with cross-functional teams to ensure reliable, data-driven solutions that impr...

San Francisco, CARemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.