Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.
Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.
Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.
Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.
Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.
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Director Architecture - Remote
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Lead strategic initiatives in enterprise voice and collaboration technologies, ensuring secure, scalable communication services. Drive modernization, manage vendor relationships, and oversee a multi-m...
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$110K - $130K *
Lead the charge in managing complex clinical trials, ensuring timely delivery, budget adherence, and high-quality outcomes while collaborating with multidisciplinary teams and stakeholders to enhance...
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Senior Manager, Regulatory Affairs
$120K - $145K *
Transform regulatory strategies for rare disease and cardio-pulmonary drug-device programs. Collaborate with cross-functional teams to ensure compliance and drive successful submissions globally, supp...
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2 days ago
Director of Strategic Partnerships
$100K - $150K *
Transform the future of business development by building strategic partnerships across key professional services. Drive growth through relationship-building and co-closing deals, while shaping a natio...
2 weeks ago
$80K - $95K *
Advance cross-functional project management efforts by leading strategic initiatives that drive business objectives and enhance care programs while ensuring timely delivery and stakeholder alignment...
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Director, AI Platforms & Engineering
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Shape the future of AI platforms by leading strategy, architecture, and engineering for scalable, secure solutions. Drive innovation while ensuring compliance and operational excellence across enterpr...
4 days ago
$90K - $140K *
Drive project success in clinical research by managing cross-functional teams, ensuring timely deliverables, and maintaining regulatory compliance. Leverage your expertise to enhance operational effic...
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Medical Director, Virtual Urgent Care & On-Demand Telehealth (Build & Scale 24/7 Service)
$335K - $387K *
Shape the future of virtual care by leading a dynamic clinical team, enhancing patient access, and driving innovative health solutions. This role combines clinical leadership with operational excellen...
2 weeks ago
$160K - $200K *
Elevate your career by leading strategic planning initiatives that drive actionable insights. Collaborate with diverse teams, mentor future leaders, and innovate in the digital space to shape impactfu...
1 week ago
Clinical Documentation Manager
$111K *
Unlock potential by leading Clinical Documentation Integrity operations, enhancing physician engagement, and driving performance improvement. Collaborate with diverse teams to ensure compliance and op...
3 weeks ago
Senior Clinical Integration Coordinator
$79K - $127K *
Help us drive efficiencies in physician preference item management, foster relationships, and maintain compliance across our Neurosurgical and Orthopedic services while achieving significant savings g...
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Director of Program Management
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Drive cross-functional execution to align teams and deliver impactful systems. Lead complex initiatives, manage dependencies, and enhance operational practices as the organization scales. Foster colla...
3 weeks ago
Auditor Clinical Validation Outpatient Specialty Clinical
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Advance your career by auditing outpatient and specialty claims, ensuring coding accuracy and compliance. Leverage your clinical and coding expertise to enhance audit processes and contribute to quali...
3 weeks ago
Program Manager, Global Strategic Accounts
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Drive program success by coordinating cross-functional teams, managing reporting, and optimizing engagement strategies for a global enterprise account, ensuring alignment with client goals and employe...
1 week ago
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Unlock potential by leading a team of Pharmacovigilance Scientists to ensure compliant, high-quality safety surveillance for clinical products. Collaborate with cross-functional teams to identify and...
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Assoc Dir, Neuro Thought Leader Liaison (West region)
$190K - $225K *
Empower commercial strategies by building relationships with key thought leaders in rare neurological diseases, capturing insights to inform brand development and launch planning, and ensuring impactf...
Reposted today
Regional Sales Manager, Strategic
$110K - $130K *
Tackle new business acquisition by executing strategic sales processes to foster relationships and drive revenue growth in the healthcare IT sector. Collaborate cross-functionally while presenting sol...
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Director, Marketing Strategy and Operations
$172K - $290K *
Transform the marketing landscape by owning critical cross-functional projects. Drive initiatives from conception through execution, aligning teams around strategic goals while adapting to evolving bu...
Reposted 3 weeks ago
$120K - $135K *
Champion revenue growth by building strategic customer relationships, driving sales through prospecting, expert consultations, and tailored proposals. Collaborate effectively to meet client needs and...
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Manager, Central Operations Quality Support - Remote
$80K - $95K *
Transform operational excellence by leading a dynamic team to enhance client satisfaction, streamline processes, and drive continuous improvement across remote Central Operations. Collaborate with pee...
2 weeks ago
$85K - $125K *
Contribute to acquiring and managing data partnerships, collaborating with product teams to prioritize and improve dataset quality, while leveraging AI to enhance data processes and achieve business o...
Reposted 2 weeks ago
$150K - $180K *
Transform cloud infrastructure by leading strategy, team development, and automation. Drive security, reliability, and cost management while collaborating across functions to enhance operational excel...
6 days ago
Operational Business Management, Manager
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Lead cross-functional initiatives to optimize operational efficiency, budget planning, and resource allocation, fostering collaboration across business units to drive organizational goals and financia...
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What does a Director of Clinical Operations do?
A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.
What qualifications are typically required for Director, Clinical Operations jobs?
Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.
Where do Directors of Clinical Operations work?
They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.
How much do Director, Clinical Operations jobs pay?
Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.
How can I find Director, Clinical Operations jobs?
Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.