Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$100K - $120K *

Transform marketing operations by building AI-driven analytics and reporting systems. Collaborate with leadership to enhance pipeline visibility and drive data-informed decisions, ensuring effective c...

Boston, MARemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$160K - $240K *

Join us to lead transformative P2P product strategies, enhancing procurement and payment processes globally. Collaborate with finance teams and vendors to drive AI integration, ensuring compliance and...

Chicago, ILRemote

2 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$150K - $180K *

Lead a dynamic account management team, driving strategic relationships with major health systems. Foster high-touch engagement, ensuring customer success and operational excellence while directly man...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$108K - $130K *

Grow enterprise software and AI delivery governance by defining standards, enhancing processes, and ensuring compliance. Lead the development of frameworks for traditional and AI solutions, driving co...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$210K - $240K *

Elevate your career by leading and optimizing Workday HCM practices, ensuring excellence in project delivery, client satisfaction, and team performance while managing complex client needs and driving...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$101K - $152K *

Champion innovative solutions by leveraging Epic expertise to enhance operational efficiency and drive strategic initiatives across healthcare environments, ensuring high-performance standards and cli...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$150K - $180K *

Shape the future of revenue operations by leading cross-functional teams, optimizing processes, and driving strategic initiatives to enhance pipeline efficiency and forecasting accuracy in a dynamic e...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Technical Services

$165K - $210K *

Drive the Medical Information strategy for infigratinib, ensuring high-quality, compliant content delivery. Collaborate cross-functionally to support scientific exchange and operational excellence in...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$134K - $230K *

Lead strategic initiatives in enterprise voice and collaboration technologies, ensuring secure, scalable communication services. Drive modernization, manage vendor relationships, and oversee a multi-m...

Eden Prairie, MNRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Lead the charge in managing complex clinical trials, ensuring timely delivery, budget adherence, and high-quality outcomes while collaborating with multidisciplinary teams and stakeholders to enhance...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Transform regulatory strategies for rare disease and cardio-pulmonary drug-device programs. Collaborate with cross-functional teams to ensure compliance and drive successful submissions globally, supp...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$151K - $302K *

Explore a leadership role driving growth and strategy in government health consulting. Collaborate with teams to enhance service delivery, manage vendor relationships, and support talent development w...

Washington, DCRemote

2 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$100K - $150K *

Transform the future of business development by building strategic partnerships across key professional services. Drive growth through relationship-building and co-closing deals, while shaping a natio...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Legal & Accounting

$80K - $95K *

Advance cross-functional project management efforts by leading strategic initiatives that drive business objectives and enhance care programs while ensuring timely delivery and stakeholder alignment...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$105K - $165K *

Shape the future of AI platforms by leading strategy, architecture, and engineering for scalable, secure solutions. Drive innovation while ensuring compliance and operational excellence across enterpr...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $140K *

Drive project success in clinical research by managing cross-functional teams, ensuring timely deliverables, and maintaining regulatory compliance. Leverage your expertise to enhance operational effic...

CanadaRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$335K - $387K *

Shape the future of virtual care by leading a dynamic clinical team, enhancing patient access, and driving innovative health solutions. This role combines clinical leadership with operational excellen...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$160K - $200K *

Elevate your career by leading strategic planning initiatives that drive actionable insights. Collaborate with diverse teams, mentor future leaders, and innovate in the digital space to shape impactfu...

Chicago, ILRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$111K *

Unlock potential by leading Clinical Documentation Integrity operations, enhancing physician engagement, and driving performance improvement. Collaborate with diverse teams to ensure compliance and op...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$79K - $127K *

Help us drive efficiencies in physician preference item management, foster relationships, and maintain compliance across our Neurosurgical and Orthopedic services while achieving significant savings g...

Pennsylvania, USRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$180K - $200K *

Drive cross-functional execution to align teams and deliver impactful systems. Lead complex initiatives, manage dependencies, and enhance operational practices as the organization scales. Foster colla...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Media

$95K *

Advance your career by auditing outpatient and specialty claims, ensuring coding accuracy and compliance. Leverage your clinical and coding expertise to enhance audit processes and contribute to quali...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$130K - $160K *

Drive program success by coordinating cross-functional teams, managing reporting, and optimizing engagement strategies for a global enterprise account, ensuring alignment with client goals and employe...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$190K - $225K *

Empower commercial strategies by building relationships with key thought leaders in rare neurological diseases, capturing insights to inform brand development and launch planning, and ensuring impactf...

RemoteRemote

Reposted today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Tackle new business acquisition by executing strategic sales processes to foster relationships and drive revenue growth in the healthcare IT sector. Collaborate cross-functionally while presenting sol...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.