Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.
Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.
Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.
Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.
Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.
System Director IT Project Management - Information Systems Applications - FT - Day
$125K - $150K *
Join us to lead strategic initiatives in project and service management, enhancing portfolio visibility and governance across Information Systems. Drive operational excellence and foster collaboration...
2 weeks ago
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Join a team that's shaping high-impact strategies and narratives for enterprise growth. Collaborate with senior leaders to craft compelling pitches and support organic initiatives, driving success acr...
Reposted 1 week ago
Senior Legal Contract Manager (US)
$78K - $156K *
Join a dynamic team as you manage complex commercial contracts, balancing legal and business needs. Collaborate with cross-functional stakeholders to drive negotiations and enhance contracting process...
Reposted 5 days ago
CMC Program Lead - Illuccix and Gozellix
$125K - $150K *
Join a team that's dedicated to advancing radiopharmaceuticals! Lead CMC strategies and cross-functional collaboration to ensure successful readiness for commercial viability, market expansion, and co...
3 weeks ago
Sr. Manager, Strategy - Oncology & Multispecialty
$120K - $145K *
Join a dynamic strategy team to analyze oncology and specialty care initiatives, building models and providing insights that guide leadership decisions across various commercial segments...
Reposted 3 weeks ago
$162K - $243K *
Shape the future of clinical research by leading cross-functional teams to optimize project delivery, ensuring quality and compliance while managing resources and budgets effectively across global cli...
4 days ago
Head of Clinical Development, Pulse
$108K - $171K *
Join us to lead clinical development for an innovative AI cardiometabolic care solution. Collaborate cross-functionally to ensure clinical excellence in product features, workflows, and member experie...
2 weeks ago
Vice President, Revenue Operations
$150K - $175K *
Transform revenue operations by leading systems, data, and processes that unify Sales, Marketing, and Customer Success into a streamlined revenue engine, driving growth and efficiency across the organ...
2 weeks ago
$82K - $111K *
Serve as the primary client liaison, driving satisfaction and retention while fostering partnerships and implementing effective client strategies for healthcare products. Collaborate cross-functionall...
4 weeks ago
Associate Vice President, Clinical Services - Market Access Marketing
$180K - $220K *
Lead the charge in developing clinical content strategies and overseeing teams within the market access practice. Drive innovation, enhance client strategies, and ensure high standards in service deli...
Reposted 2 weeks ago
Associate Director Pharmacovigilance
$125K - $150K *
Transform pharmacovigilance processes by leading compliance and quality initiatives, ensuring adherence to regulations while enhancing patient safety and product excellence across generics and biosimi...
3 weeks ago
Associate Director, Client Services
$110K - $130K *
Shape the future of client partnerships by leading loyalty strategies and cross-functional teams to enhance retail programs, driving measurable impact and client satisfaction in a fast-paced environme...
1 week ago
Senior Director, Alliance Management
$242K - $290K *
Empower strategic partnerships by managing alliances, driving collaboration, and ensuring alignment with organizational goals. Leverage your expertise to foster trust and deliver impactful outcomes in...
Today
Director, Practice Development
$125K - $150K *
Drive strategic growth by managing client accounts and expanding market share. Collaborate with internal teams to deliver tailored solutions and ensure client satisfaction while mentoring team members...
4 days ago
Transaction Management Director - Healthcare
$175K - $220K *
Shape the future of healthcare real estate by leading a dynamic transaction management team. Oversee negotiations, staff development, and strategic planning to drive client success and enhance operati...
3 days ago
Sr. Director - Product Operations
$160K - $200K *
Lead the charge in developing and scaling the product operating model, ensuring organizational effectiveness, agile execution, and strategic alignment. Collaborate across teams to foster a culture of...
Reposted 2 weeks ago
Program Executive, Drug Development and Commercial
$285K - $325K *
Drive transformational patient impact by leading cross-functional teams and executing strategic drug development programs in an agile environment. Foster collaboration and accountability to deliver in...
Reposted 1 week ago
$187K - $210K *
Champion operational excellence by leading Product Operations, driving innovation, and optimizing workflows. Manage a dedicated team to enhance product delivery, streamline processes, and ensure align...
1 week ago
$195K - $245K *
Champion AI strategy and implementation in healthcare, leading a team to deliver measurable value. Drive business development, client engagement, and practice growth while shaping innovative solutions...
1 week ago
IT Service Delivery Program Manager, Healthcare
$110K - $130K *
Empower healthcare IT delivery by managing a dynamic team, ensuring operational excellence, and driving EMR performance. Collaborate with clinical stakeholders to enhance patient care through effectiv...
6 days ago
Manager, Contact Center and Clinical Operations
$122K - $158K *
Join a team that's dedicated to operational excellence in pharmacy care. Lead clinical operations, enhance patient experiences, and foster a culture of continuous improvement while ensuring compliance...
1 week ago
Associate Director, Marketing, Lung Patient
$186K - $233K *
Shape impactful marketing strategies for lung cancer programs, collaborating with cross-functional teams to drive patient engagement and launch readiness. Lead initiatives that align with brand goals...
Today
Senior Manager, Revenue Operations
$156K - $195K *
Own the end-to-end B2B2C enrollment funnel by transforming data into actionable insights, optimizing processes, and leading cross-functional collaboration to enhance growth and ensure successful membe...
Reposted 3 weeks ago
$205K - $265K *
Empower your career by optimizing sales operations and driving efficiency. Collaborate with cross-functional teams to enhance processes, manage forecasts, and implement strategic initiatives that supp...
1 week ago
Director - QualityOne Strategy Operations
$125K - $300K *
Champion strategic growth by partnering with executive leadership to drive operational excellence, enhance data integrity, and lead cross-functional initiatives that propel business expansion and prod...
6 days ago
What does a Director of Clinical Operations do?
A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.
What qualifications are typically required for Director, Clinical Operations jobs?
Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.
Where do Directors of Clinical Operations work?
They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.
How much do Director, Clinical Operations jobs pay?
Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.
How can I find Director, Clinical Operations jobs?
Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.