Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.
Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.
Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.
Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.
Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.
Director, CMS & HHS Business Development
$182K - $250K *
Champion market development strategies to enhance our presence in CMS and HHS. Leverage your expertise to build relationships, identify opportunities, and drive impactful outcomes in federal health IT...
2 weeks ago
$150K - $180K *
Contribute to the design and execution of clinical studies, ensuring data integrity and quality. Collaborate cross-functionally to drive study activities and support regulatory efforts, while enhancin...
1 week ago
Principal Scientist, In Vivo Pharmacology, Neurology
$173K - $205K *
Shape the future of neurology by leading in vivo pharmacology studies, collaborating with cross-functional teams, and driving data-driven decisions for IND submissions in a dynamic biotech environment...
3 weeks ago
$80K - $95K *
Drive quality assurance excellence by leading the development of scalable processes that enhance student recruitment and enrollment, ensuring compliance and continuous improvement across all interacti...
1 week ago
Medical Director, Population Health & Clinical Governance - Remote
$180K - $220K *
Take ownership of clinical integrity and quality oversight in population health management. Drive evidence-based standards and ensure compliance with accreditation requirements while collaborating wit...
4 weeks ago
Medical Director - Inpatient Review
$223K - $313K *
Collaborate with a dedicated team of physicians to ensure high-quality inpatient care through clinical expertise, thorough reviews, and utilization management. Advance patient outcomes by utilizing st...
Reposted 3 weeks ago
Senior Program Manager, Health Coaching
$161K - $202K *
Analyze business operations to drive strategic improvements in health coaching. Collaborate with cross-functional teams to enhance program outcomes, utilizing data-driven insights and effective commun...
3 weeks ago
$213K - $243K *
Champion the development of a robust commercial data strategy, ensuring high-quality, AI-ready data solutions that drive impactful decision-making and enhance commercial performance across the organiz...
2 weeks ago
Clinical Trial Manager II, Dermatology & Rheumatology CRO, USA
$100K - $120K *
Engage with a dynamic CRO to oversee clinical monitoring and enhance site performance. Foster relationships, ensure compliance with regulations, and lead a team in delivering quality outcomes in clini...
Reposted 3 weeks ago
Manager, Clinical Science & Site Educator
$160K - $175K *
Champion a high-performing team to deliver clinical and scientific education at trial sites. Engage directly with stakeholders to enhance site support, improve recruitment, and ensure protocol complia...
4 weeks ago
Director, Clinical Documentation Integrity - Remote
$112K - $193K *
Shape the future of clinical documentation integrity across six hospitals in AZ and NV. Lead operations, enhance documentation practices, and collaborate with healthcare leaders to drive performance a...
1 week ago
Product Manager, Clinical Programs & Case Management
$86K - $138K *
Unlock innovative healthcare solutions by leading product strategy and lifecycle management for clinical programs. Collaborate across teams to enhance member experiences and drive business value while...
1 week ago
Executive Director, HIMS Services
$150K - $180K *
Transform healthcare administration by leading enterprise-wide HIMS operations, ensuring compliance and driving performance improvement across a multi-state network while fostering an engaged workforc...
4 weeks ago
$113K - $197K *
Lead regulatory and compliance oversight for Operations, ensuring accuracy and efficiency. Collaborate with enterprise partners to enhance operational processes, implement automation, and drive contin...
3 days ago
Director of Business Operations
$125K - $150K *
Transform business operations by leading systems and technology initiatives that enhance efficiency, drive AI enablement, and streamline processes across the organization, ensuring a robust foundation...
1 week ago
$190K - $220K *
Lead the legal function by managing commercial agreements and advising on compliance. Collaborate with business teams to ensure rapid deal execution while mitigating risks. Drive process improvements...
3 weeks ago
$160K - $200K *
Join a team that's redefining forensics and collections globally. Lead a skilled team, enhance operational efficiency, and drive client engagement while ensuring compliance and defensibility across re...
1 week ago
$110K - $130K *
Lead the creative vision and execution of impactful design assets, enhancing brand identity and streamlining production processes using AI tools. Collaborate across teams to deliver high-quality marke...
2 weeks ago
$130K - $165K *
Lead clinical data management efforts by overseeing project timelines, ensuring quality deliverables, and facilitating communication among stakeholders. Drive data integrity and compliance while mento...
1 week ago
Director or Senior Director of Translational Medicine
$235K - $310K *
Join a team that empowers translational medicine innovation in early-phase oncology, owning strategies from IND-enabling studies to proof of concept. Drive impactful biomarker integration and clinical...
Reposted 1 week ago
Manager, Clinical Publications & Scientific Specialist
$95K - $115K *
Lead the charge in developing and communicating clinical evidence for innovations. Collaborate with cross-functional teams to manage research, publications, and scientific communications, ensuring imp...
4 days ago
Director, Delivery & Deployment Excellence
$184K - $230K *
Lead the charge in transforming business readiness and deployment excellence across the Americas, ensuring seamless Oracle E-Business Suite upgrades while aligning regional priorities with global stra...
Today
$201K - $251K *
Lead strategic forecasting initiatives to drive decision-making in oncology. Collaborate with cross-functional teams to develop long-term models and communicate insights that shape product and portfol...
1 week ago
21GRAMS- Associate Medical Strategy Director
$120K - $135K *
Join a team that shapes innovative medical strategies, driving excellence in healthcare content. Collaborate with experts, cultivate client relationships, and inspire teams to elevate project outcomes...
Reposted 1 week ago
$110K - $130K *
Manage a dedicated team to enhance patient access to complex medications, ensuring operational excellence and compliance while delivering exceptional experiences. Guide strategic improvements to optim...
Reposted 3 weeks ago
What does a Director of Clinical Operations do?
A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.
What qualifications are typically required for Director, Clinical Operations jobs?
Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.
Where do Directors of Clinical Operations work?
They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.
How much do Director, Clinical Operations jobs pay?
Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.
How can I find Director, Clinical Operations jobs?
Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.