Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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1,000+

Dentist Jobs in Pennsylvania

Sort By: Relevance

$250K - $300K *

Elevate patient care by leading an adult kidney transplant program, overseeing clinical and regulatory operations while mentoring fellows and residents in a collaborative academic environment...

2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Shape the future of procurement by leading strategic sourcing initiatives, enhancing vendor relationships, and driving financial transparency. Collaborate across teams to streamline processes and leve...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$87K - $136K *

Shape the future of enterprise operations by leading a dynamic team to craft compelling RFP responses, ensuring compliance and strategic alignment while driving productivity and process improvements a...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$210K - $250K *

Join us to provide comprehensive care as a General Neurologist, collaborating with a dynamic team in a busy clinic. Engage in education and research while enhancing community health across a multi-hos...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Advance healthcare solutions by driving sales of innovative diagnostic instruments. Engage with key stakeholders to promote QIAstat-Dx systems, ensuring successful adoption and customer satisfaction t...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Shape the future of patient care by delivering exceptional pharmaceutical services. You'll develop and monitor evidence-based medication therapy plans, ensuring safety and efficacy while enhancing pat...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Join a dedicated team to deliver exceptional pharmaceutical care, ensuring safe and effective medication therapy while enhancing patient outcomes and quality of life through evidence-based practices a...

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$136K - $220K *

Unlock project management excellence in Global Regulatory Affairs, driving timelines and compliance for drug submissions. Collaborate cross-functionally to ensure accurate documentation and effective...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$104K - $125K *

Transform medical equipment planning by collaborating with clients and staff to develop comprehensive equipment lists, ensuring adherence to standards while managing vendor relationships and project c...

2 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$90K - $95K *

Transform patient care by leading a neuro rehabilitation team while providing hands-on therapy. This role combines clinical expertise with leadership, ensuring quality outcomes for individuals recover...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Make your mark at a community-focused care facility by leading the Resident Care Department. Drive quality care, support staff, and enhance resident experiences while ensuring compliance with all stan...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Unlock potential by leading the design and optimization of enterprise workflows. Collaborate with cross-functional teams to enhance operational efficiency and drive data-driven decisions within a dyna...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$110K - $150K *

Shape the future of legal operations by optimizing workflows, managing technology, and driving automation. Collaborate with cross-functional teams to enhance efficiency and support a rapidly growing g...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Consumer Technology

$141K - $175K *

Lead the charge in managing a team of Nurse Practitioners, ensuring quality care for CKD patients through clinical oversight, training, and strategic operational initiatives while collaborating with l...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Join a team that's shaping secure identity solutions across the enterprise. Lead the design and implementation of identity and access controls, ensuring compliance and operational efficiency while col...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$360K - $400K *

Empower our team by driving innovative solutions and enhancing operational efficiency. Collaborate across departments to streamline processes and improve service delivery, ensuring alignment with stra...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Oversee clinical operations and staff management to ensure safe, efficient patient care. Collaborate on strategic planning and maintain high standards of clinical practice while fostering a supportive...

2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$160K - $192K *

Optimize commercial performance by engaging healthcare providers and driving product adoption. Collaborate with cross-functional teams to support launches and enhance patient access to innovative ther...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$90K - $110K *

Transform complex clinical data into compelling copy that resonates. Collaborate with cross-functional teams to create impactful healthcare campaigns, ensuring accuracy and brand voice across diverse...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Unlock potential by leading compliance audits, ensuring accurate coding and documentation in anesthesia. Collaborate with teams to mitigate risks, deliver training, and maintain regulatory standards w...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$110K - $166K *

Optimize site contract management by reviewing, drafting, and negotiating various legal agreements. Collaborate with clinical teams to ensure timely deliverables and serve as a subject matter expert i...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$135K - $170K *

Accelerate growth by managing strategic healthcare accounts, driving new business, and enhancing relationships. Collaborate with cross-functional teams to address complex identity challenges and deliv...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$90K - $110K *

Join a team that supports physicians in delivering exceptional patient care through assessment, planning, and clinical assistance, ensuring high-quality healthcare services in a collaborative environm...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$115K - $125K *

Elevate virtual health services by leading strategic initiatives, enhancing patient experiences, and driving operational excellence. Collaborate across teams to implement innovative care models and en...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $150K *

Champion social strategy and community engagement, driving impactful growth across multiple channels. Lead a dynamic team to create culturally relevant content, leveraging AI for efficiency and innova...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.