Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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1,000+

Dentist Jobs in Pennsylvania

Sort By: Relevance

$150K - $180K *

Accelerate progress at driving revenue growth through strategic sales initiatives, building client relationships, and enhancing cybersecurity solutions for organizations, while managing the complete s...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$139K - $163K *

Advance your career as a strategic legal partner by providing product and privacy counsel that balances compliance with innovation. Collaborate across teams to develop scalable solutions that support...

United StatesRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$100K - $120K *

Engage in proactive recruitment to attract top-performing Account Executives in the non-QM mortgage sector. Blend talent acquisition with market intelligence for strategic sourcing and relationship-bu...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$150K - $180K *

Transform the commercial landscape by building a scalable sales engine, driving strategic deals, and leading with innovation in a dynamic life sciences environment. Collaborate closely with leadership...

Reposted today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $85K *

Grow your career with a dynamic team focused on client success, managing relationships, and delivering tailored solutions. Drive satisfaction and retention while collaborating across departments to en...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$230K - $260K *

Champion high-quality behavioral healthcare by delivering exceptional outpatient services. Collaborate with a dedicated clinical team to enhance patient care while enjoying flexible schedules and a su...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$135K - $160K *

Pioneer the future of AI as a Senior Engineer specializing in semantic web technologies, bridging business and tech to create scalable data solutions that enhance analytics, knowledge management, and...

RemoteRemote

1 month ago

  •   5 - 7 years exp.  •   Information Technology

$95K - $115K *

Join a team that's dedicated to providing urgent care services, performing patient exams, and collaborating with physicians. Manage a diverse patient load while delivering quality care in a supportive...

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$75K - $112K *

Innovate with us to enhance store layouts and fixture plans, driving project execution and collaboration across teams. Leverage your expertise in architecture and design to deliver impactful retail en...

2 days ago

  •   5 - 7 years exp.  •   Food & Beverages

$110K - $130K *

Deliver strategic leadership across 13-17 veterinary locations, ensuring operational excellence, quality care, and growth. Collaborate with teams to enhance performance and foster a positive culture w...

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$108K - $196K *

Shape the future of healthcare by managing client relationships and optimizing clinical programs. Collaborate with teams to drive client success and ensure alignment with company goals, leveraging dat...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Drive impactful strategies by leveraging research and insights to advance government health opportunities. Collaborate with leaders to enhance competitive positioning and secure meaningful work that b...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Legal & Accounting

$95K - $115K *

Empower your career by providing analytic support for performance improvement and labor productivity initiatives. Collaborate with leaders to develop standards, enhance data integrity, and optimize be...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Elevate sales effectiveness by managing CRM tools and processes. Ensure user training, drive adoption, and analyze data to enhance sales strategies. Collaborate with teams to implement best practices...

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$75K - $90K *

Transform the HR landscape in a dynamic healthcare setting by managing operations, supporting talent acquisition, and fostering a positive workplace culture while collaborating with centralized HR tea...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $200K *

Transform lives by providing virtual therapy and developing personalized treatment plans. Collaborate with a dedicated team to deliver compassionate, evidence-based care while enjoying the flexibility...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$160K - $192K *

Deliver exceptional sales and support within the healthcare sector, building productive relationships with providers while driving product adoption and ensuring patient access to innovative therapies...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Empower our pharmacy operations by leading a dedicated team to ensure high-quality, compliant services across multiple locations, enhancing patient care and operational efficiency through strategic ov...

2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$180K - $216K *

Empower small businesses by leading our omni-channel marketing strategy. Drive customer acquisition and retention through innovative campaigns, optimizing performance across digital and traditional ch...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$200K *

Shape the future of enrollment management by leading strategic initiatives, overseeing admissions, financial aid, and student accounts, while fostering collaboration across departments to enhance stud...

1 week ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$122K - $212K *

Take ownership of process optimization and digital operations to enhance Clinical Risk Management. Drive user engagement, coordinate vendor relations, and ensure audit readiness while implementing str...

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$122K - $212K *

Join a dynamic team to enhance Clinical Risk Management through process optimization and digital operations. Drive user engagement, coordinate vendor relations, and ensure audit readiness while implem...

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$122K - $212K *

Help us drive operational excellence in Clinical Risk Management by optimizing processes and managing digital operations. Collaborate with stakeholders to enhance user engagement and ensure audit read...

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$180K - $215K *

Unlock potential by leading regional sales efforts for a groundbreaking product. Drive performance through strategic execution, team leadership, and customer engagement in a fast-paced, entrepreneuria...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$114K - $182K *

Join a team that's transforming orthopaedic solutions through innovative strategies and commercial leadership. Drive growth and enhance patient outcomes by managing key initiatives across the Sports S...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.