Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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1,000+

Dentist Jobs in Pennsylvania

Sort By: Relevance

$115K - $135K *

Shape the future of clinical trials by leading site monitoring efforts, ensuring compliance, and fostering collaboration across teams. Drive quality and efficiency in trial execution while mentoring j...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$137K - $235K *

Lead the charge in shaping customer master data strategy, connecting cross-functional teams to ensure trusted information drives commercial success and operational excellence in the pharmaceutical ind...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$190K - $252K *

Join a team that's redefining professional coding leadership, overseeing coding operations, quality audits, and education initiatives. Drive strategic objectives that enhance patient care and revenue...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$132K - $195K *

Transform risk management by leading assessments, negotiating treatment plans, and enhancing controls. Collaborate cross-functionally to ensure compliance and proactively address security risks while...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$75K - $112K *

Join a team that champions the execution of innovative Fixture Plans and Store Layouts, enhancing the shopping experience across new stores and remodels while collaborating with cross-functional teams...

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$125K - $140K *

Optimize your career by managing enterprise-wide database environments, ensuring high availability, executing disaster recovery strategies, and supporting critical operations in a dynamic SaaS ecosyst...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Lead the clinical pharmacy team to ensure safe, effective medication management and optimize patient care. Oversee staff, develop programs, and maintain compliance while fostering collaboration with h...

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Redefine pharmaceutical care by managing staff and overseeing medication processes. Ensure quality, safety, and cost-effectiveness in drug therapy while collaborating with healthcare professionals to...

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $110K *

Help us deliver exceptional imaging services by managing operations, ensuring patient safety, and fostering a collaborative environment. Oversee staff performance and enhance center efficiency while d...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Accelerate progress at driving revenue growth through strategic sales initiatives, building client relationships, and enhancing cybersecurity solutions for organizations, while managing the complete s...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$139K - $163K *

Advance your career as a strategic legal partner by providing product and privacy counsel that balances compliance with innovation. Collaborate across teams to develop scalable solutions that support...

United StatesRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$100K - $120K *

Engage in proactive recruitment to attract top-performing Account Executives in the non-QM mortgage sector. Blend talent acquisition with market intelligence for strategic sourcing and relationship-bu...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$80K - $85K *

Grow your career with a dynamic team focused on client success, managing relationships, and delivering tailored solutions. Drive satisfaction and retention while collaborating across departments to en...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$230K - $260K *

Champion high-quality behavioral healthcare by delivering exceptional outpatient services. Collaborate with a dedicated clinical team to enhance patient care while enjoying flexible schedules and a su...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$135K - $160K *

Pioneer the future of AI as a Senior Engineer specializing in semantic web technologies, bridging business and tech to create scalable data solutions that enhance analytics, knowledge management, and...

RemoteRemote

1 month ago

  •   5 - 7 years exp.  •   Information Technology

$95K - $115K *

Join a team that's dedicated to providing urgent care services, performing patient exams, and collaborating with physicians. Manage a diverse patient load while delivering quality care in a supportive...

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$75K - $112K *

Innovate with us to enhance store layouts and fixture plans, driving project execution and collaboration across teams. Leverage your expertise in architecture and design to deliver impactful retail en...

2 days ago

  •   5 - 7 years exp.  •   Food & Beverages

$110K - $130K *

Deliver strategic leadership across 13-17 veterinary locations, ensuring operational excellence, quality care, and growth. Collaborate with teams to enhance performance and foster a positive culture w...

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$80K - $95K *

Drive impactful strategies by leveraging research and insights to advance government health opportunities. Collaborate with leaders to enhance competitive positioning and secure meaningful work that b...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Legal & Accounting

$95K - $115K *

Empower your career by providing analytic support for performance improvement and labor productivity initiatives. Collaborate with leaders to develop standards, enhance data integrity, and optimize be...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Elevate sales effectiveness by managing CRM tools and processes. Ensure user training, drive adoption, and analyze data to enhance sales strategies. Collaborate with teams to implement best practices...

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$75K - $90K *

Transform the HR landscape in a dynamic healthcare setting by managing operations, supporting talent acquisition, and fostering a positive workplace culture while collaborating with centralized HR tea...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $200K *

Transform lives by providing virtual therapy and developing personalized treatment plans. Collaborate with a dedicated team to deliver compassionate, evidence-based care while enjoying the flexibility...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$160K - $192K *

Deliver exceptional sales and support within the healthcare sector, building productive relationships with providers while driving product adoption and ensuring patient access to innovative therapies...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Empower our pharmacy operations by leading a dedicated team to ensure high-quality, compliant services across multiple locations, enhancing patient care and operational efficiency through strategic ov...

2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.