Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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1,000+

Dentist Jobs in Pennsylvania

Sort By: Relevance

$150K - $180K *

Innovate with us to build scalable legal frameworks that support rapid growth. As a strategic advisor, you'll manage complex agreements, corporate governance, and leverage AI to enhance operational ef...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Partner with us to design and implement cloud-native data solutions, ensuring secure and reliable data exchange across platforms. Collaborate with teams to enhance data accessibility and support advan...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$140K - $155K *

Empower teams to elevate product design through strategic vision, fostering collaboration across disciplines to create impactful digital experiences that meet user needs and business goals while ensur...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$82K - $99K *

Advance your career by providing exceptional outpatient orthopedic care. Collaborate with a diverse patient mix and orthopedic physicians in a supportive environment focused on compliance and communic...

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$84K - $100K *

Advance your career as a Physical Therapist in a dynamic outpatient setting. Collaborate with a diverse patient population and orthopedic specialists while ensuring compliance and delivering exception...

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$82K *

Join a team that's dedicated to providing exceptional outpatient therapy. As a Physical Therapist, you'll work with a diverse patient mix, gaining valuable experience in orthopedic and neurological ca...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$82K - $90K *

Join a dynamic team of physical therapists in an outpatient setting, providing exceptional care for a diverse range of orthopedic and neurological conditions. Collaborate with specialists to enhance p...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$78K - $95K *

Join a team that's dedicated to providing exceptional outpatient care. This role involves evaluating and treating a diverse patient population while collaborating with a skilled team in a supportive e...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$107K - $142K *

Contribute to patient care by performing advanced interventional procedures, collaborating with a multidisciplinary team, and engaging in professional development and research to enhance pediatric hea...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$76K - $114K *

Empower healthcare innovation by providing clinical and technical support to customers. Collaborate with surgical teams, enhance product knowledge, and ensure optimal system performance in a dynamic f...

Philadelphia, PARemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$76K - $114K *

Champion innovative clinical solutions by providing expert support and training to healthcare professionals. Drive customer engagement and enhance surgical outcomes through technical assistance and re...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$256K - $302K *

Partner with us to oversee and enhance psychiatric services, integrating clinical supervision and administrative leadership to ensure high-quality patient care and compliance with healthcare standards...

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$256K - $302K *

Elevate psychiatric services by overseeing operations, ensuring quality care, and fostering collaboration among clinical teams. Lead initiatives for policy governance, staff development, and direct pa...

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$180K - $215K *

Shape the future of our commercial launch by leading a regional sales team to drive market entry, foster customer relations, and exceed performance goals in a dynamic, cross-functional environment...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Join a team that's dedicated to defending Medical Malpractice cases, where you'll collaborate with experienced attorneys to enhance your legal skills and advance your career in a supportive, inclusive...

Today

  •   Less than 5 years exp.  •   Legal & Accounting

$120K - $145K *

Drive financial leadership in outpatient clinics, guiding senior management on metrics, budgeting, and performance enhancement to optimize operations and support strategic growth initiatives across th...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $110K *

Provide comprehensive healthcare services, including evaluations, treatments, and patient education, while collaborating with physicians. Engage in quality improvement initiatives and maintain patient...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Collaborate with HR and legal teams to provide comprehensive employment law support, drafting and negotiating contracts while ensuring compliance with regulations. Balance legal risks with business ob...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$95K - $115K *

Contribute to the mental health community by providing direct support, conducting evaluations, and developing rehabilitation plans while maintaining current knowledge of psychiatric practices and tren...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$117K - $156K *

Drive major gifts fundraising by cultivating donor relationships and leading a team. Collaborate with senior leadership to strategize and enhance philanthropic efforts, ensuring impactful support for...

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$105K - $150K *

Transform healthcare insights by leading client engagements with real-world data. Drive business development and project delivery while building long-term client relationships in a dynamic, hybrid wor...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Contribute to exceptional patient care by supporting intensivists and enhancing treatment plans. Your expertise will help in monitoring, diagnosing, and mentoring, ensuring optimal health outcomes in...

4 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Engage your expertise to lead client relationships and drive strategic initiatives in healthcare advertising. Oversee project execution, ensure compliance, and collaborate with teams to elevate client...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Transform client relationships by leading operational excellence and cross-functional initiatives. Drive service quality and satisfaction for complex clients while mentoring team members and enhancing...

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$115K - $158K *

Shape the future of Medicaid wellness by leading innovative strategies and solutions that enhance health outcomes for underserved populations. Collaborate with diverse teams to develop impactful progr...

RemoteRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.