Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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1,000+

Dentist Jobs in Pennsylvania

Sort By: Relevance

$120K - $130K *

Manage financial reporting and internal controls, leading a team to ensure accurate, timely financial statements while driving continuous improvement and collaboration across departments to support bu...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$129K - $171K *

Unlock the potential of veterinary research by overseeing animal care, compliance, and training. Collaborate with stakeholders to develop innovative animal models and ensure regulatory adherence, enha...

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$58K - $106K *

Build trust and excitement by delivering safe, joyful ear-piercing experiences. Leverage nursing expertise to ensure customer comfort, maintain a sterile environment, and support studio operations whi...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$97K - $133K *

Empower your career by managing data lifecycles, ensuring data accessibility, and driving business insights through innovative data solutions and architectures. Collaborate across teams to enhance dat...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$113K - $188K *

Shape the future of healthcare reimbursement by developing and implementing payment policies that enhance accuracy, compliance, and provider experience in a dynamic payer environment. Collaborate with...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$108K - $162K *

Join a team that's dedicated to enhancing biomedical service operations. Lead a skilled team of technicians, ensuring high-quality support and customer satisfaction across the Pacific Northwest while...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Business Services

$90K - $110K *

Empower your career by delivering high-quality healthcare services, collaborating with physicians, and advocating for patients. Engage in diagnostics, treatment planning, and education while participa...

Today

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Empower the clinical support team by coordinating complex cases, mentoring junior counselors, and enhancing protocols. Your expertise will drive effective communication and quality standards in geneti...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Join a team that's shaping clinical sales strategies and enhancing client relationships. Lead initiatives that drive market growth and improve patient satisfaction while collaborating across disciplin...

Harrisburg, PARemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Unlock potential by providing advanced emergency care across all age groups, collaborating closely with physicians and APP supervisors to ensure high-quality patient outcomes in a dynamic, fast-paced...

6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$180K - $215K *

Drive regional sales success by leading launch execution, building high-performing teams, and fostering customer relationships. Leverage strong business acumen and collaborative skills to achieve sale...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$90K - $115K *

Champion clinical excellence by leading and mentoring a dynamic ECM team, ensuring comprehensive patient care and adherence to individualized plans, while collaborating effectively with multidisciplin...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$156K - $234K *

Join a dynamic team to lead the development of AI-driven customer success platforms, enhancing post-sale experiences through innovative technology and automation, while collaborating closely with engi...

RemoteRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Legal & Accounting

$210K - $250K *

Transform pediatric surgical care by joining our team as a key physician. Engage in patient care, education, and research while mentoring the next generation of medical professionals in a dynamic clin...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$123K - $207K *

Elevate enterprise systems by leading design and enhancements, ensuring reliability and usability. Collaborate with cross-functional teams to translate requirements into scalable solutions while drivi...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Real Estate & Construction

$150K - $180K *

Drive impactful scientific communication by overseeing content development across therapeutic areas, ensuring strategic alignment with client goals while managing a team and collaborating with various...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$125K - $160K *

Join a dynamic team as a Sr. Health Benefit Plan Consulting Attorney, leveraging your expertise in healthcare law to navigate complex regulatory issues, support consulting services, and drive complian...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$125K - $146K *

Lead clinical pharmacy services to ensure safe, effective specialty infusion therapies. Collaborate with healthcare teams to enhance patient outcomes through medication management and operational supp...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$297K - $367K *

Grow your career with a pivotal role driving hospital data integration and compliance. Lead execution of clinical data operations, build relationships, and ensure secure data handling while shaping a...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $125K *

Lead the charge in transforming cardiac care by providing expert clinical and technical support for mapping and navigation systems, driving innovation and enhancing patient outcomes across multiple ac...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$85K - $100K *

Join a team that's dedicated to providing exceptional veterinary care, leveraging advanced technology and collaborative support. You'll thrive in a nurturing environment, empowered to enhance the live...

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$160K - $192K *

Join a team that's driving commercial success by engaging healthcare providers, building relationships, and supporting innovative therapies. Your expertise will be pivotal in executing business plans...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$107K - $142K *

Shape the future of clinical operations by providing leadership and oversight to ensure efficient hospital flow, patient safety, and staff performance while fostering a culture of excellence and conti...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$135K - $160K *

Elevate our deal desk function by transforming processes into a scalable model. You'll implement AI tools, streamline order forms, and ensure efficient deal structuring while collaborating with cross...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$195K - $225K *

Drive security innovation by shaping technical strategies and frameworks that protect sensitive data and systems. Collaborate across teams to embed security practices, mentor engineers, and ensure com...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.