Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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1,000+

Dentist Jobs in Pennsylvania

Sort By: Relevance

$95K - $115K *

Join a team that's dedicated to providing high-quality outpatient urologic care. As an Advanced Practice Provider, you'll independently manage diverse urologic conditions, ensuring patient-centered se...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$262K - $394K *

Accelerate progress at Clio Phones by leading the growth of a cloud-native VoIP platform for law firms. Own P&L, build operational plans, and drive market strategy while managing cross-functional team...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Legal & Accounting

$120K - $145K *

Engage in cutting-edge AI development by designing and scaling intelligent applications. Leverage Generative AI and modern tools to enhance productivity and integrate workflows within healthcare platf...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Healthcare

$114K - $236K *

Advance your career by providing expert veterinary pathology support and mentorship in a dynamic laboratory setting. Engage in diagnostic services and enhance training programs for residents and stude...

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$95K - $115K *

Join a dynamic team to develop innovative software solutions for medical devices, collaborating across disciplines from design to release while enhancing user experience and meeting clinical needs in...

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$160K - $200K *

Lead the charge in transforming operations through strategic execution, technology integration, and process optimization to elevate client experiences, enhance scalability, and foster a high-performan...

Reposted 3 weeks ago

  •   11 - 15 years exp.  •   Legal & Accounting

$68K - $91K *

Elevate patient care by providing specialized nursing in hemodialysis units, ensuring quality outcomes through collaboration with care teams and ongoing patient education. Enjoy a supportive environme...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $87K *

Deliver strategic leadership in managing resident technology programs, enhancing operational efficiency, and improving resident satisfaction. Collaborate broadly across teams to drive metrics, project...

United StatesRemote

Reposted 1 month ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$120K - $145K *

Elevate healthcare reimbursement processes by leading legal strategies on billing disputes and regulatory compliance. Collaborate with teams to create innovative solutions and build legal frameworks t...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Engage with cross-functional leaders to elevate product strategy and execution. Drive innovation in product development, leveraging AI to enhance customer value and business performance across a diver...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$160K - $200K *

Champion community health by collaborating with a dedicated team of CRNAs and anesthesiologists. Engage in diverse specialties, including orthopedic and pediatric anesthesia, while enjoying a supporti...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$160K - $200K *

Advance your career by leading a high-quality anesthesiology team, collaborating with dedicated clinicians in a dynamic environment that fosters professional satisfaction and integrated care across va...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Unlock your potential as a strategic advisor in ambulatory operations, enhancing patient access and workforce optimization across a complex healthcare network. Lead initiatives that drive efficiency a...

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$101K - $146K *

Unlock potential by leading payer contract negotiations to enhance relationships, optimize revenue, and ensure compliance with regulations, all while aligning with strategic priorities of the health s...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$160K - $200K *

Join a team that's redefining customer acquisition in the P&C insurance market. Drive strategic partnerships, enhance demand management, and support innovative solutions to elevate our marketplace to...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$95K - $115K *

Transform clinical quality by supporting training initiatives, monitoring clinician performance, and ensuring compliance with quality standards for successful operational processes and clinician suppo...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Champion operational excellence by leading a dynamic team to enhance patient care, optimize revenue cycles, and drive strategic initiatives across multiple sites, ensuring compliance and fostering gro...

Today

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$150K - $180K *

Lead the development and execution of innovative intellectual property strategies, ensuring effective product clearance and robust patent portfolio management. Collaborate across departments to drive...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Healthcare

$201K - $393K *

Lead the development and execution of global clinical trials for women's health compounds, collaborating with cross-functional teams to shape clinical strategies and ensure compliance with regulatory...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $132K *

Join a team that's dedicated to enhancing cybersecurity measures across cloud environments. Lead initiatives in data protection, compliance, and security awareness while mentoring peers and implementi...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$250K - $300K *

Advance your career by providing expert hematopathology services, engaging in multidisciplinary collaboration, and contributing to education and research at a leading academic medical center...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $225K *

Pioneer innovative design solutions as a Staff Product Designer, driving AI-powered workflows and enhancing user experiences in a complex legal tech environment. Collaborate closely with engineering t...

RemoteRemote

6 days ago

  •   11 - 15 years exp.  •   Legal & Accounting

$98K - $125K *

Lead the charge in sourcing and procurement for New Product Introductions, ensuring supplier readiness and cost efficiency. Collaborate with cross-functional teams to drive strategic sourcing initiati...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $110K *

Analyze healthcare data to enhance clinical insights and improve medication use. Collaborate with cross-functional teams to develop analytics tools and real-world evidence studies, driving better heal...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Join a team that's redefining telehealth by delivering exceptional psychotherapy to older adults. Enjoy flexible hours, comprehensive support, and opportunities for professional growth while making a...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.