Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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$90K - $150K *

Join a team that's dedicated to ensuring software quality by developing and executing comprehensive tests. Collaborate with peers to enhance testing methodologies and mentor teammates in a dynamic and...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$155K - $210K *

Empower your career by leading enterprise database architecture and transformation initiatives. Collaborate with executive stakeholders to drive innovation and establish best practices in modern data...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Join a team that's transforming healthcare by connecting groundbreaking products with clients. You'll lead onboarding, design impactful use cases, and advocate for customer success, ensuring seamless...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Manage civil construction estimates for EV charging projects, ensuring accurate pricing and proposal development. Collaborate with teams and stakeholders to identify risks and optimize project executi...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Energy & Utilities

$87K - $120K *

Elevate customer success by managing IT projects, driving business development, and ensuring seamless platform integration for enterprise clients, enhancing satisfaction and ROI through effective solu...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$158K - $195K *

Accelerate progress at the intersection of agriculture and technology by leading strategic engagement with key stakeholders in the pork value chain, driving commercialization efforts, and fostering in...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$173K - $255K *

Join a dynamic team to enhance product security throughout the development lifecycle. Collaborate with engineering and product teams to identify vulnerabilities, automate processes, and implement secu...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$105K - $155K *

Unlock potential by driving enterprise acquisition in Health, Beauty & Wellness. Lead outreach and negotiations with high-value merchants, shaping strategic partnerships that generate activated revenu...

RemoteRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$104K - $143K *

Lead the charge in developing and delivering innovative technology solutions for managing Medicare/Medicaid plans. Collaborate with cross-functional teams to drive product vision, strategy, and execut...

RemoteRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Elevate customer success by guiding clients through their journey, maximizing product value, and fostering strategic partnerships. Collaborate cross-functionally to enhance user experience and drive r...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$126K - $236K *

Lead the charge in consumer engagement and growth strategy, driving awareness and deepening user connections across channels. Collaborate cross-functionally to optimize campaigns that inspire action a...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Media

$275K - $325K *

Drive the growth of healthcare practices by owning strategy, partnerships, and P&L. Collaborate with teams to deliver tailored financial solutions, while leveraging your network to establish Flex as t...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$150K - $195K *

Drive change management initiatives that enhance employee engagement and operational efficiency. Collaborate across teams to ensure successful adoption of technology and policy changes, while providin...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Lead the charge in enhancing organizational security by developing security frameworks, assessing controls, and collaborating with technical teams to create a resilient security architecture for moder...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Information Technology

$244K - $279K *

Reimagine the future of small business spend and credit by driving innovation and shaping architecture. Collaborate with cross-functional teams to enhance B2B platforms, leverage AI, and mentor others...

RemoteRemote

4 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$96K - $120K *

Accelerate progress at the forefront of digital banking by leading complex client implementations, resolving advanced technical issues, and ensuring successful delivery of innovative solutions that al...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$129K - $162K *

Develop and lead actuarial processes for Medicare Value-Based Care, managing monthly results, payer settlements, and special projects. Collaborate with cross-functional teams to enhance analytics and...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Shape the future of customer support by enhancing AI workflows and automation. Collaborate with teams to optimize performance, improve tools, and deliver personalized experiences as we scale our innov...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $105K *

Join a specialized team to evaluate biological research, ensuring safety against misuse. Utilize your expertise to distinguish legitimate science from potential threats, contributing to AI safety and...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Business Services

$150K - $180K *

Elevate operational excellence by standardizing workflows and driving accountability across multiple sites. Lead a high-performing team to ensure consistent patient access and optimize performance met...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Elevate security standards by leading bug bounty programs, conducting audits, and enhancing software supply chain security. Collaborate across teams to build innovative tools that protect users and en...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$95K - $124K *

Transform corporate legal operations by managing due diligence, governance, and vendor relationships. Collaborate across teams to ensure compliance and streamline processes, while supporting attorneys...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$120K - $140K *

Lead the charge in delivering innovative healthcare solutions by engaging with clients, understanding their needs, and providing technical guidance throughout the sales process to drive successful out...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $200K *

Accelerate progress at the forefront of product innovation, leading a team to drive strategy and customer experience for a key transaction management platform while embedding AI to enhance efficiency...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$114K - $167K *

Engineer innovative ERP solutions by analyzing complex business processes, defining architecture, and leading integration efforts to optimize performance and ensure compliance. Drive impactful customi...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.