Explore $100K+ Jobs in Colorado

Discover professional opportunities across Colorado with Ladders, where you can search vetted jobs paying $100,000 or more. From Denver and Boulder to Colorado Springs, Fort Collins, and beyond, explore roles across industries and experience levels.

Find Opportunities Across Colorado

Colorado’s employment landscape includes opportunities in technology, healthcare, finance, engineering, energy, aerospace, and business leadership. Search statewide listings or focus on a city or region that fits your career goals and preferred lifestyle.

Advance Your Career

Whether you’re pursuing a senior leadership role, a specialized professional position, or your next career move, use Ladders to discover openings that align with your experience. Review job requirements, responsibilities, location, and compensation details to identify roles worth exploring.

Search Vetted Professional Jobs

Ladders focuses on professional opportunities with salaries of $100,000 or more. Browse Colorado listings, compare roles, and apply to positions that match your qualifications. Job availability and salary information can vary by employer and posting.

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1,000+

Jobs in Colorado

Average Salary in USD

Average Salary: $114,421

Sort By: Relevance

$80K - $95K *

Join a team that's redefining virtual fundraising by leading innovative campaigns that engage diverse audiences, cultivate partnerships, and drive sustainable revenue growth, all while supporting a me...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$150K - $170K *

Unlock the potential of enterprise data architecture by designing secure, scalable solutions for employee data using Databricks. Collaborate with cross-functional teams to implement governance, compli...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$100K - $120K *

Drive revenue growth by cultivating relationships and managing the full-cycle sales process in the healthcare technology sector. Utilize AI-driven solutions to enhance client performance and deliver v...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$128K - $146K *

Join a team that's optimizing enterprise AI platforms to enhance document workflows. You will integrate user-facing layers, create analytics dashboards, and deliver actionable insights, driving effici...

Reposted today

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $95K *

Join a team that's transforming client websites into growth engines through data-driven conversion rate optimization. Collaborate with cross-functional experts to analyze user behavior, run A/B tests...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Enterprise Technology

$175K - $190K *

Champion supply chain excellence by leading assessments and transformations. Drive operational improvements across procurement, manufacturing, and logistics while managing client relationships and del...

Today

  •   8 - 10 years exp.  •   Business Services

$100K - $120K *

Optimize customer engagement by leveraging technical expertise to drive sales, enhance relationships, and expand market share for pneumatic and control systems. Collaborate with teams to deliver tailo...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$90K - $110K *

Elevate customer success by managing renewals for a diverse portfolio of 250 partners. Utilize data-driven insights to enhance relationships, drive retention, and identify growth opportunities in a fa...

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$165K - $210K *

Drive the Medical Information strategy for infigratinib, ensuring high-quality, compliant content delivery. Collaborate cross-functionally to support scientific exchange and operational excellence in...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$74K - $139K *

Join us to drive program performance by integrating planning, scheduling, and execution across functions. You'll develop compliant schedules, analyze critical paths, and provide actionable insights to...

Today

  •   Less than 5 years exp.  •   Aerospace & Defense

$80K - $95K *

Transform customer relationships and drive revenue growth by managing account strategies, identifying upsell opportunities, and collaborating with cross-functional teams to enhance product adoption an...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$65K - $121K *

Transform testing processes by developing automated scripts and overseeing subsystem tests. Collaborate across disciplines to ensure integration and troubleshoot anomalies, all while thriving in a dyn...

Today

  •   Less than 5 years exp.  •   Aerospace & Defense

$79K - $147K *

Join our team as a Quality Engineer, ensuring top-tier quality in spacecraft components through rigorous testing and continuous improvement. Collaborate with cross-functional teams to uphold standards...

Today

  •   Less than 5 years exp.  •   Aerospace & Defense

$111K - $147K *

Develop and implement advanced tracking algorithms and real-time software systems to enhance air and missile defense capabilities, collaborating with cross-functional teams to ensure operational effec...

Today

  •   Less than 5 years exp.  •   Aerospace & Defense

$111K - $147K *

Join our innovative team to design and implement advanced tracking algorithms for air and missile defense systems, ensuring real-time processing of airborne threats while collaborating with cross-func...

Today

  •   Less than 5 years exp.  •   Aerospace & Defense

$120K *

Champion the delivery of cross-functional initiatives, aligning teams and strategies to drive measurable business impact while fostering collaboration and continuous improvement in a dynamic environme...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$161K - $268K *

Lead the charge in building trusted partnerships with oncology care teams, executing strategic business plans to enhance patient access and outcomes. Collaborate with cross-functional teams to drive m...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$161K - $268K *

Manage a defined territory to build partnerships with oncology teams, executing business plans that enhance patient access and deliver results. Collaborate with cross-functional teams to drive patient...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$161K - $268K *

Join us to build trusted partnerships with oncology care teams, executing strategic business plans that enhance patient access and drive measurable outcomes. Collaborate with cross-functional teams to...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$161K - $268K *

Engage with oncology care teams to build partnerships and execute business plans that enhance patient access and outcomes. Collaborate cross-functionally to drive measurable results and support local...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $175K *

Pioneer insights at the intersection of Sales, Marketing, and CS by owning and enhancing analytical infrastructure to generate decision-ready insights that drive growth in a dynamic, fast-paced enviro...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Information Technology

$129K - $231K *

Reimagine drug discovery as you lead molecular pharmacology efforts in neuroscience. Collaborate across teams to develop strategies, interpret data, and advance innovative therapies for sleep-wake dis...

RemoteRemote

Reposted today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $105K *

Join a specialized team to evaluate biological research, ensuring safety against misuse. Utilize your expertise to distinguish legitimate science from potential threats, contributing to AI safety and...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Business Services

$135K - $160K *

Join a dynamic team to architect and implement a next-gen Design System, ensuring consistent, accessible experiences across products. Collaborate with cross-functional teams to drive technical alignme...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Food & Beverages

$201K - $251K *

Elevate access strategies and marketing initiatives for oncology products, focusing on non-clinical value propositions. Collaborate cross-functionally to ensure successful product launches and effecti...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs can I find in Colorado?question toggle

    Listings may include professional roles in technology, healthcare, finance, engineering, energy, aerospace, and management. Available positions and qualifications vary by employer.

  • Which Colorado cities can I search for jobs in?question toggle

    Explore jobs in Denver, Boulder, Colorado Springs, Fort Collins, and other locations across Colorado. Use location filters to narrow your search.

  • Are the Colorado jobs on Ladders vetted?question toggle

    Ladders features vetted professional job opportunities that pay $100,000 or more. Check each posting for current details, employer requirements, and compensation information.

  • How can I find a Colorado job that matches my experience?question toggle

    Search by job title, location, industry, and other criteria, then compare the responsibilities and qualifications in each listing with your background and career goals.