Explore $100K+ Jobs in Colorado

Discover professional opportunities across Colorado with Ladders, where you can search vetted jobs paying $100,000 or more. From Denver and Boulder to Colorado Springs, Fort Collins, and beyond, explore roles across industries and experience levels.

Find Opportunities Across Colorado

Colorado’s employment landscape includes opportunities in technology, healthcare, finance, engineering, energy, aerospace, and business leadership. Search statewide listings or focus on a city or region that fits your career goals and preferred lifestyle.

Advance Your Career

Whether you’re pursuing a senior leadership role, a specialized professional position, or your next career move, use Ladders to discover openings that align with your experience. Review job requirements, responsibilities, location, and compensation details to identify roles worth exploring.

Search Vetted Professional Jobs

Ladders focuses on professional opportunities with salaries of $100,000 or more. Browse Colorado listings, compare roles, and apply to positions that match your qualifications. Job availability and salary information can vary by employer and posting.

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1,000+

Jobs in Colorado

Average Salary in USD

Average Salary: $114,421

Sort By: Relevance

$130K - $155K *

Lead the charge in driving end-to-end strategy and discovery for complex client engagements. Collaborate with cross-functional teams to deliver actionable insights, build trusted relationships, and na...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$95K - $115K *

Transform the learning landscape by leading the design and development of innovative educational materials. You'll engage diverse teams to create immersive, high-quality training experiences using cut...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $125K *

Elevate healthcare operations by leading credentialing and medical staff services across multiple states. Drive compliance, streamline onboarding, and enhance workflows to support over 200 professiona...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$91K - $178K *

Grow your career by managing cloud cybersecurity solutions on AWS. Collaborate with teams to ensure compliance with RMF standards while deploying automated security measures and conducting vulnerabili...

1 week ago

  •   5 - 7 years exp.  •   Business Services

$167K - $208K *

Unlock potential by serving as a strategic HR partner, driving talent strategies and leading acquisition integrations to enhance organizational effectiveness and employee engagement across business un...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$98K - $150K *

Empower future leaders in healthcare by directing the Health Systems Leadership Track. This role combines teaching, curriculum development, and academic leadership, fostering a diverse and inclusive l...

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$130K - $160K *

Champion quality assurance excellence by leading testing automation and system reliability initiatives across critical transit and tolling platforms. Drive high-impact strategies and mentor teams in a...

1 week ago

  •   5 - 7 years exp.  •   Transportation

$80K - $95K *

Join a team that's driving growth in mid-market healthcare by building relationships, managing a dynamic sales pipeline, and closing new business opportunities in a fast-paced SaaS environment...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$144K - $288K *

Drive innovative digital product strategies for chronic condition management, leading cross-functional teams to enhance patient care pathways and optimize outcomes through technology integration and o...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$125K - $185K *

Join a team that's driving strategic sourcing excellence in Facilities for Retail accounts. Lead a dedicated team to deliver innovative solutions, manage supplier relationships, and ensure high-qualit...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Business Services

$175K - $210K *

Champion the transformation of GPU infrastructure into scalable AI clouds. Lead pre-sales strategy, build a high-performing team, and drive technical wins in complex enterprise deals, shaping the futu...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$80K - $95K *

Drive product strategy and vision by collaborating with cross-functional teams, managing backlogs, and leveraging AI to enhance customer value. Ensure alignment between business needs and product deve...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$175K - $210K *

Drive the execution of a comprehensive medical affairs plan for prostate cancer theranostics, collaborating across functions to enhance strategy, launch readiness, and lifecycle planning while advanci...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$78K - $206K *

Unlock potential by leading clinical performance improvement projects for Medicare Provider Collaboration groups. Collaborate with teams to enhance population health outcomes, focusing on Stars qualit...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$175K - $210K *

Champion the execution of a comprehensive medical affairs plan for renal cancer theranostics, driving cross-functional alignment and strategic initiatives to enhance patient outcomes and advance clini...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$85K - $105K *

Empower innovation as you develop NGS assays, conduct experiments, and analyze results. Collaborate with teams to enhance existing products and present findings at conferences, driving advancements in...

1 week ago

  •   Less than 5 years exp.  •   Business Services

$73K - $114K *

Champion patient care by delivering proficient nursing services in a dynamic, 24/7 acute care environment. Collaborate with multidisciplinary teams to optimize patient outcomes and provide education t...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$91K - $91K *

Engage in the critical support of surgical procedures, ensuring efficiency and safety in the operating room. Collaborate with medical teams to prepare and maintain equipment, assist with patient care...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$115K - $144K *

Lead the charge in optimizing CORE banking operations by managing a dedicated team, ensuring system efficiency, and implementing strategic changes to enhance business services and member experience...

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$250K - $300K *

Shape the future of AI-driven platforms by designing scalable applications and intelligent workflows. Lead initiatives that enhance operational efficiency and enable real-time insights, while mentorin...

United StatesRemote

Reposted 1 week ago

  •   11 - 15 years exp.  •   Real Estate & Construction

$140K - $160K *

Innovate by leading global Credit & Collections operations, driving cash performance, and managing customer credit risk. Collaborate with cross-functional teams to enhance processes, ensure compliance...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Information Technology

$133K - $186K *

Join a dedicated team to innovate spaceflight technologies, focusing on the development and testing of advanced Motion Control systems while collaborating across disciplines to ensure quality and safe...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$96K - $181K *

Elevate your career by leading risk-based internal audits, collaborating with business leaders to enhance governance and control processes. Drive audit planning, execution, and team development while...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$114K - $190K *

Build a resilient Site Reliability Engineering practice, leading a global team to enhance cloud platform reliability, scalability, and operational excellence while fostering collaboration and continuo...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$81K - $93K *

Join a team that's dedicated to promoting dental health and providing exceptional oral hygiene services. As a key player, you'll enhance patient care through preventive treatments and education while...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs can I find in Colorado?question toggle

    Listings may include professional roles in technology, healthcare, finance, engineering, energy, aerospace, and management. Available positions and qualifications vary by employer.

  • Which Colorado cities can I search for jobs in?question toggle

    Explore jobs in Denver, Boulder, Colorado Springs, Fort Collins, and other locations across Colorado. Use location filters to narrow your search.

  • Are the Colorado jobs on Ladders vetted?question toggle

    Ladders features vetted professional job opportunities that pay $100,000 or more. Check each posting for current details, employer requirements, and compensation information.

  • How can I find a Colorado job that matches my experience?question toggle

    Search by job title, location, industry, and other criteria, then compare the responsibilities and qualifications in each listing with your background and career goals.