Explore $100K+ Jobs in Colorado

Discover professional opportunities across Colorado with Ladders, where you can search vetted jobs paying $100,000 or more. From Denver and Boulder to Colorado Springs, Fort Collins, and beyond, explore roles across industries and experience levels.

Find Opportunities Across Colorado

Colorado’s employment landscape includes opportunities in technology, healthcare, finance, engineering, energy, aerospace, and business leadership. Search statewide listings or focus on a city or region that fits your career goals and preferred lifestyle.

Advance Your Career

Whether you’re pursuing a senior leadership role, a specialized professional position, or your next career move, use Ladders to discover openings that align with your experience. Review job requirements, responsibilities, location, and compensation details to identify roles worth exploring.

Search Vetted Professional Jobs

Ladders focuses on professional opportunities with salaries of $100,000 or more. Browse Colorado listings, compare roles, and apply to positions that match your qualifications. Job availability and salary information can vary by employer and posting.

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1,000+

Jobs in Colorado

Average Salary in USD

Average Salary: $114,421

Sort By: Relevance

$115K - $130K *

Champion executive compensation strategies by managing program administration, collaborating with HR partners, and conducting market research to enhance compensation practices and support organization...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$139K - $188K *

Unlock potential by leading regulatory writing for complex submissions, mentoring junior writers, and driving departmental initiatives. Collaborate with cross-functional teams to ensure compliance and...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $115K *

Champion financial insights and strategic modeling for home services, partnering with stakeholders to drive growth. Leverage FP&A expertise to manage budgets, forecasts, and variance analysis, ensurin...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$130K - $150K *

Empower our High Net Worth Planning Services by providing expert financial strategies. Engage with advisors to deliver tailored solutions, addressing complex planning issues while mentoring junior tea...

RemoteRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$145K - $220K *

Drive impactful product marketing strategies for proactive security solutions, guiding market positioning, launches, and customer engagement. Collaborate with cross-functional teams to shape product d...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$77K - $118K *

Join a dynamic team to manage long haul fiber projects, ensuring timely delivery and adherence to budgets while coordinating with vendors and stakeholders to meet customer expectations and operational...

Colorado, USRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $145K *

Empower regulatory excellence by guiding cross-functional teams in compliance and strategy. Leverage deep FDA knowledge to influence promotional materials and ensure adherence to evolving regulations...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Drive regulatory strategy across major programs, leading high-impact submissions and authority engagement. Collaborate with cross-functional teams to optimize clinical development and ensure complianc...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Champion global labeling strategy for innovative therapies, leading complex initiatives from development to post-approval. Collaborate with cross-functional teams to ensure compliance and high-quality...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Join a team that's advancing global health by supporting critical clinical trial submissions. In this role, you'll lead regulatory strategies, ensure compliance, and collaborate with diverse teams to...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$107K - $150K *

Engage with clients to design and implement advanced Physical Security Systems. Collaborate with top engineers on complex projects, ensuring high-quality solutions and customer satisfaction while mana...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $85K *

Champion the future of auditing by leading operational, financial, and compliance audits. Collaborate with diverse teams to enhance internal controls and drive efficiency, ensuring adherence to best p...

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$86K - $142K *

Lead and execute performance and compliance audits, guiding a team to enhance local government efficiency and effectiveness while ensuring adherence to auditing standards and quality control...

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$68K - $113K *

Unlock potential by conducting performance audits and evaluations of government functions. Collaborate with a dynamic team to ensure compliance and efficiency while producing quality reports for diver...

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$192K - $252K *

Champion digital transformation by optimizing medical technology solutions and enhancing HCP engagement strategies. Drive adoption and value realization of innovative tools across Field Medical teams...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$137K - $182K *

Architect and drive AI-powered applications for drug development, focusing on protocol generation and clinical trials. Lead technical direction, mentor engineers, and ensure compliance while fostering...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Lead the charge in overseeing industrial construction projects, ensuring quality and efficiency. Utilize your expertise to manage teams, coordinate schedules, and drive project success while traveling...

1 week ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$123K - $169K *

Drive your career with end-to-end management of new product development programs, ensuring alignment across teams and delivering innovative solutions for critical digital infrastructure in a dynamic e...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$176K - $243K *

Drive product portfolio expansion for Modular Datacenter Infrastructure, ensuring market leadership through strategic planning, P&L management, and fostering innovation. Lead a diverse team to enhance...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Join a team that's shaping the future of restaurant development by partnering with franchisees to identify, secure, and build new locations. Drive growth through strategic site evaluations, negotiatio...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Food & Beverages

$112K - $154K *

Lead the charge in advanced testing and validation of aerospace systems, utilizing your expertise to solve complex technical problems and guide less experienced engineers in a collaborative, multi-dis...

1 week ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$151K - $314K *

Shape the future of global ERP delivery by leading a diverse team, executing strategic initiatives, and driving transformation across multiple regions to enhance operational efficiency and business va...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$100K - $162K *

Drive sales success in the Southern IL territory by developing strategic business plans, conducting impactful presentations, and fostering strong relationships with healthcare professionals to achieve...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $162K *

Drive success by developing strategic sales plans and fostering relationships in your territory. Achieve sales goals through effective presentations and ethical practices while continuously enhancing...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $162K *

Drive sales growth in assigned territory by developing strategic plans, conducting impactful presentations, and fostering strong relationships with healthcare professionals while adhering to ethical p...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs can I find in Colorado?question toggle

    Listings may include professional roles in technology, healthcare, finance, engineering, energy, aerospace, and management. Available positions and qualifications vary by employer.

  • Which Colorado cities can I search for jobs in?question toggle

    Explore jobs in Denver, Boulder, Colorado Springs, Fort Collins, and other locations across Colorado. Use location filters to narrow your search.

  • Are the Colorado jobs on Ladders vetted?question toggle

    Ladders features vetted professional job opportunities that pay $100,000 or more. Check each posting for current details, employer requirements, and compensation information.

  • How can I find a Colorado job that matches my experience?question toggle

    Search by job title, location, industry, and other criteria, then compare the responsibilities and qualifications in each listing with your background and career goals.