Find $100K+ Jobs in Colorado

Discover high-paying professional jobs across Colorado with Ladders. Browse vetted opportunities with salaries of $100,000 or more in Denver, Boulder, Colorado Springs, Fort Collins, and other communities throughout the state. Whether you’re looking to advance in your current field or take the next step in your career, explore roles that match your experience and goals.

Explore Colorado’s Professional Job Market

Colorado offers opportunities across a range of industries, including technology, aerospace, healthcare, finance, energy, and professional services. Employers in the state hire for roles in major metro areas as well as growing regional markets. Search current listings to see which positions, locations, and employers align with your career plans.

Find Opportunities in Denver, Boulder, and Beyond

From Denver’s broad business community to Boulder’s technology and research ecosystem, Colorado’s cities offer varied professional opportunities. You can also explore jobs in Colorado Springs, Fort Collins, and other locations. Use location and role preferences to focus your search on opportunities that fit your needs.

Search Vetted Jobs Paying $100,000 or More

Ladders focuses on professional positions with salaries of at least $100,000. Browse Colorado job listings, review role requirements, and compare opportunities based on your background and priorities. New openings may be added regularly, so revisit the page to see the latest available jobs.

Take the Next Step in Your Colorado Career

Explore high-paying jobs in Colorado and find roles that support your professional growth. Search by job title, industry, or location to discover opportunities that suit your experience.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down
1,000+

Jobs in Colorado

Average Salary in USD

Average Salary: $114,421

Sort By: Relevance

$119K - $175K *

Optimize healthcare compliance by leading regulatory assurance efforts, ensuring adherence to HIPAA, HITECH, and HITRUST standards while collaborating with clinical leadership to maintain a defensible...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Information Technology

$90K - $115K *

Join a team that's dedicated to ensuring financial accuracy and integrity. In this role, you'll manage month-end close processes, support audits, and enhance accounting practices while mentoring junio...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$95K - $178K *

Empower a dynamic team by driving technical planning and system integration, ensuring effective solutions that meet customer requirements while navigating technical, schedule, and cost constraints in...

Today

  •   Less than 5 years exp.  •   Aerospace & Defense

$150K - $230K *

Champion your career by driving oncology product success and building impactful relationships with healthcare professionals. Leverage your expertise to enhance patient access and deliver innovative so...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$150K - $230K *

Champion the promotion of oncology products, building strong relationships with healthcare stakeholders while driving performance goals and ensuring patient access to innovative therapies in a dynamic...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$150K - $230K *

Join a team that's dedicated to advancing oncology care by promoting innovative products and building strong relationships with healthcare professionals. Leverage your expertise to drive brand value a...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$150K - $230K *

Drive impactful oncology solutions by building relationships with key stakeholders. Leverage your expertise to exceed performance goals and enhance patient access to innovative therapies while managin...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$150K - $230K *

Drive impactful oncology product promotion by building strong relationships with key stakeholders. Leverage clinical expertise and market insights to exceed performance goals while ensuring patient ac...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$150K - $230K *

Empower your career by driving oncology product success through strategic relationships and innovative solutions. Lead market engagement, exceed performance goals, and enhance patient access while col...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$150K - $230K *

Transform the future of oncology care by driving product success and building strong relationships with key stakeholders. Lead initiatives that enhance patient access and deliver innovative solutions...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$150K - $230K *

Champion the promotion of oncology products, building strong relationships with healthcare professionals to enhance patient access and drive brand value in a competitive market. Lead strategic initiat...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$176K - $207K *

Unlock potential by building and deploying ML systems that enhance core products. Collaborate with cross-functional teams to design, code, and monitor AI services, ensuring high performance and alignm...

Today

  •   5 - 7 years exp.  •   Consumer Technology

$73K - $102K *

Drive innovative SAP solutions by developing and implementing Fiori applications, enhancing ABAP capabilities, and collaborating with teams to meet client needs in a dynamic environment...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$98K - $135K *

Join a dynamic team to manage enterprise PKI, oversee certificate lifecycles, and implement security controls. Contribute to infrastructure modernization and incident investigations while ensuring rob...

Today

  •   Less than 5 years exp.  •   Aerospace & Defense

$110K - $130K *

Transform KYC operations by leading a team focused on customer onboarding and due diligence. Drive policy ownership, manage complex cases, and enhance processes through collaboration with cross-functi...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$170K - $220K *

Shape the future of customer solutions by leading implementations and driving adoption of innovative technologies. Collaborate with teams to deliver tailored architectural designs that meet strategic...

RemoteRemote

Today

  •   Less than 5 years exp.  •   Enterprise Technology

$125K - $150K *

Shape the future of fraud prevention by leading a dynamic team to analyze transactions, enhance detection rates, and innovate reporting processes, while collaborating with technical partners to refine...

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$80K - $95K *

Accelerate revenue growth by strategically acquiring K-12 education customers. Drive new business opportunities, represent the brand, and deliver tailored solutions to enhance cybersecurity awareness...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$95K - $115K *

Transform mission capabilities as a Hardware Engineer, collaborating in a multi-discipline team to innovate and implement cutting-edge radar technology for Space Domain and Missile Warning systems...

Today

  •   Less than 5 years exp.  •   Aerospace & Defense

$125K - $155K *

Grow your career with a dynamic team focused on designing and implementing scalable systems. Collaborate on complex projects, mentor peers, and drive technical excellence while contributing to impactf...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Enterprise Technology

$128K - $188K *

Transform strategic growth initiatives by partnering with executives to solve complex challenges, drive alignment across teams, and enhance customer experiences in a fast-paced communications and AI l...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Transportation

$118K - $196K *

Transform client outcomes through innovative problem-solving and project management in power systems consulting. Engage in impactful research and data analysis to enhance climate resilience and sustai...

RemoteRemote

Reposted today

  •   5 - 7 years exp.  •   Business Services

$73K - $114K *

Empower patient care by providing exceptional nursing services in a dynamic, multidisciplinary environment. Collaborate with a dedicated team to enhance wellness and deliver evidence-based practices f...

Today

  •   Less than 5 years exp.  •   Healthcare

$86K - $129K *

Engage with executive leaders to oversee project lifecycles, managing scope, resources, and budgets. Drive multiple projects simultaneously while ensuring effective communication and stakeholder engag...

Reposted today

  •   Less than 5 years exp.  •   Healthcare

$85K - $95K *

Unlock potential by designing innovative digital experiences that inspire and engage. Collaborate with teams to create user-centered solutions, leveraging research and creativity to tackle complex cha...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Colorado?question toggle

    Colorado listings can include opportunities in technology, aerospace, healthcare, finance, energy, and other professional fields. Available roles vary by employer and location, so browse current listings for the latest openings.

  • Which Colorado cities can I search for jobs in?question toggle

    You can explore jobs in Denver, Boulder, Colorado Springs, Fort Collins, and other Colorado communities. Use location preferences to narrow your search.

  • Do Colorado jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Check each listing for its compensation details and requirements.

  • How can I find the right high-paying job in Colorado?question toggle

    Search by job title, industry, or location, then review each listing’s responsibilities and qualifications to identify opportunities that fit your experience and goals.