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Welcome to Ladders - Your Destination for Chief Scientist Jobs

Here on Ladders, we've curated a selection of the best Chief Scientist roles available in the industry. All the …

1,000+ Chief Scientist Jobs in San Francisco, CA

$ Average salary: 163,333

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  • Research Scientist, Life Sciences

    $300K — $320K *San Francisco, CA (San Francisco County)In-Person
    Explore the intersection of AI and biology, driving advancements in computational biology and empowering scientific workflows through innovative tools and model capabilities that bridge biology and machine learning.
    Requirements: Ph.D. in computational biology, 5+ years ML experience, strong Python skills.
  • Expert Protein Biochemist

    Collaborate to advance protein biochemistry through innovative research techniques, driving impactful results in molecular cloning, protein purification, and biophysical characterization in a dynamic, team-focused laboratory setting.
    Requirements: PhD in Biology/Biochemistry; 0-2 years lab experience; strong communication skills.
  • Senior Scientist, Stuctural Biology

    $172K — $221K *San Francisco, CA (San Francisco County)In-Person
    Join a team that's at the leading edge of structural biology, driving innovative drug discovery. Lead protein biochemistry efforts, mentor talent, and collaborate across functions to unlock new insights in aging and rejuvenation.
    Requirements: PhD in relevant field, 6+ years experience, high-res structure determination.
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    Research Scientist

    $225K — $300K *San Francisco, CA (San Francisco County)In-Person
    Champion advancements in clinical intelligence through research and model innovation. Drive the entire research process from problem definition to real-world impact, collaborating with engineers and clinicians in a dynamic work environment.
    Requirements: PhD or equivalent in ML/deep learning; experience in novel modeling work.
  • Expert Pharma Discovery Biologist

    Lead the charge in advancing oncology through in vitro discovery biology, collaborating across programs to validate targets and drive innovative therapeutic solutions.
    Requirements: MS in Molecular Biology/Biochemistry, 6-8 yrs in oncology drug discovery.
  • Expert Pharma Discovery Biologist

    Join a team that's pioneering in vitro discovery biology to advance oncology programs, conducting target validation and developing innovative therapies across various modalities while driving research in tumor models.
    Requirements: PhD in Molecular Biology/Biochemistry; 0-2 years of relevant experience.
  • Research Scientist

    $100K — $300K *San Francisco, CA (San Francisco County)In-Person
    Pioneer advanced research in automated reasoning and AI-driven code analysis to create innovative solutions. Collaborate cross-functionally, publish findings, and impact safety and efficiency in global infrastructure through cutting-edge technology.
    Requirements: MSc/PhD in Computer Science; expertise in automated reasoning, AI/ML.
  • Applied Scientist

    $120K — $160K *San Francisco, CA (San Francisco County)In-Person
    Advance the research frontier by leading the design and deployment of adaptive ML systems that drive real-world impact. Collaborate with teams to shape product strategy while addressing novel challenges at the intersection of technology and business.
    Requirements: 3-4 years ML experience, strong programming skills, fluency in PyTorch/JAX/TensorFlow.
  • Chief of Staff - AI Governance

    $250K — $300K *San Francisco, CA (San Francisco County)In-Person
    Reimagine operational excellence as the Chief of Staff, driving strategy and enhancing communication. Be pivotal in high-stakes meetings and lead transformative projects, shaping the future of AI governance with hands-on execution and leadership.
    Requirements: BA/BS degree, 5-7 years experience, MBB career track, startup exposure.
  • Senior Scientist, Cell Therapy Process Development

    $140K — $175K *Alameda, CA (Alameda County)In-Person
    Transform the development of cutting-edge cell therapies by leading process design, optimization, and technology transfer in a collaborative, GMP-compliant environment focused on accelerating clinical readiness for innovative genetic medicines.
    Requirements: BS/MS + 6yrs or PhD + 4yrs in biopharmaceutical process development.
  • Principal Scientist, Differential Privacy

    $130K — $180K *US-AnywhereRemote in United States
    Lead innovative research in differential privacy to shape strategies for privacy-preserving data handling, ensuring robust solutions while collaborating with NIST on advancing techniques for shared data security and utility.
    Requirements: Ph.D. in CS, 10 years experience in privacy algorithms, strong math skills.
  • Research Scientist

    $127K — $333K *San Francisco, CA (San Francisco County)In-Person
    Advance research in geriatrics by leading projects, collaborating with colleagues, and mentoring students. Drive innovation in patient-oriented research and the biology of aging while securing funding to establish an independent research program.
    Requirements: MD/PhD, ABIM certification/eligibility, demonstrated research & teaching skills.
  • Scientist, Advanced Clinical Innovation Partnerships (ACIP), IGTS, West

    $113K — $181K *US-AnywhereRemote in United States
    Lead cutting-edge clinical data and AI initiatives with top hospitals to drive innovation in image-guided therapy. Partner with key stakeholders to translate clinical needs into impactful, scalable solutions that enhance patient outcomes.
    Requirements: Master's degree in biomedical sciences; 3+ years in medical devices; AI experience.
  • Principal Applied Scientist, Sponsored Products and Brands

    $228K — $309K *Palo Alto, CA (Santa Clara County)In-Person
    Elevate brand advertising through innovative Gen AI solutions, driving product strategy and design across teams while collaborating on cutting-edge technologies to enhance user experiences and exceed business objectives.
    Requirements: PhD, 7+ years in AI/ML, systems design, product management, and engineering.
  • Scientific Strategy Lead

    $120K — $150K *US-AnywhereRemote in United States
    Drive operational improvements and business performance by translating complex data into actionable insights. Collaborate cross-functionally to enhance decision-making, foster innovation, and support strategic growth initiatives in a dynamic environment.
    Requirements: Bachelor's degree; 10+ years in life sciences; strong analytical & communication skills.
  • Chief Medical Officer

    Deliver innovative clinical strategies by leveraging AI/ML to enhance trial efficacy, spearhead successful Phase 1 and Phase 2 trials, and guide teams in optimal patient selection and dosing, reporting directly to the CEO.
    Requirements: MD or equivalent, 20+ years in clinical development, regulatory expertise.
  • Research Scientist

    $120K — $160K *San Francisco, CA (San Francisco County)In-Person
    Shape the future of search technology by advancing innovative model training methods to enhance web indexing, bridging theoretical research with practical applications for millions of users.
    Requirements: PhD in Computer Science, 3+ years in AI, expertise in transformers.
  • Research Scientist

    $120K — $160K *Palo Alto, CA (Santa Clara County)In-Person
    Join a dynamic team to innovate and scale advanced models for web indexing. Collaborate with experts and engage in cutting-edge research that impacts millions, merging search and recommendations through transformative technologies.
    Requirements: PhD in relevant field; expertise in model training; strong coding skills.
  • Chief Of Staff

    $150K — $200K *San Francisco, CA (San Francisco County)In-Person
    Transform the executive function by optimizing operations, enhancing strategic initiatives, and driving cross-functional collaboration. Serve as a pivotal partner to the CEO, maintaining focus on long-term vision while managing high-stakes priorities.
    Requirements: 3-7 years in BizOps/strategy, exceptional writing, AI product familiarity.
  • Staff Scientist, Cell Modeling

    $125K — $153K *Hayward, CA (Alameda County)In-Person
    Engineer and lead advanced physics-based simulations of solid-state battery cells, ensuring accurate model predictions and actionable insights for experimental teams. Collaborate across functional areas to drive innovation in battery technology.
    Requirements: PhD + 3 years or Master's + 6 years in relevant engineering/science fields.
  • GenAI Solutions Architect - SFL Scientific

    $128K — $252K *San Francisco, CA (San Francisco County)In-Person
    Empower organizations by architecting innovative AI solutions that drive efficiency and performance across diverse industries. Collaborate with teams to design, implement, and optimize AI systems, ensuring they align with business goals.
    Requirements: Bachelor's degree in STEM, 4+ years cloud-native AI architecture experience.
  • GenAI Solutions Architect - SFL Scientific

    $128K — $252K *San Jose, CA (Santa Clara County)In-Person
    Lead the charge in designing and implementing innovative GenAI solutions, collaborating with cross-functional teams to architect scalable, AI-driven infrastructures that meet diverse business needs and drive organizational transformation.
    Requirements: Bachelor's degree, 4+ years AI architecture experience, Python, cloud tech.
  • Senior Data Scientist

    $146K — $304K *Mountain View, CA (Santa Clara County)In-Person
    Innovate within the AI Platform Team, leading data science initiatives to enhance AI/ML capabilities. Collaborate across teams to tackle complex challenges and operationalize advanced analytics solutions for optimal performance and scalability.
    Requirements: 5+ years in data science/ML; Python; AI/ML frameworks; LLM experience.
  • Head/VP of Engineering

    $150K — $200K *San Francisco, CA (San Francisco County)In-Person
    Elevate your career by leading a strategic engineering team, defining technical vision, and driving product delivery in a collaborative, fast-paced environment focused on growth and innovation.
    Requirements: 8+ years software engineering, 2-3 years leadership, strong back-end skills.
  • Scientific Project Manager

    $105K — $130K *Fremont, CA (Alameda County)In-Person
    Lead the charge in managing complex scientific projects, ensuring successful delivery through collaboration with internal and external stakeholders, while maintaining quality and compliance with regulatory standards.
    Requirements: Bachelor's in life sciences; 3+ years in project management; SQL proficiency.
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Research Scientist, Life Sciences

Company Name
$300K — $320K *
San Francisco, CA 94112
In-Person
Pharmaceuticals & Biotech
5 - 7 years of experience
Job Description

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FAQ About Chief Scientist Jobs in San Francisco, CA

What is the role of a Chief Scientist?

A Chief Scientist is typically the head of research and development within a company. They lead innovative projects, oversee research teams, and help to drive the company's scientific trajectory.

What qualifications and experience do I need for a Chief Scientist job?

A Chief Scientist typically requires a doctorate (PhD) and substantial experience in their specific scientific field. Strong leadership and management skills are also critical.

What industries employ Chief Scientists?

Chief Scientists are employed across various industries including technology, pharmaceuticals, environmental science, and government bodies.