Chief Clinical Officer (CCO) Jobs

Explore Chief Clinical Officer jobs on Ladders, where professionals can find vetted opportunities paying $100,000 or more. Chief Clinical Officers guide clinical strategy and help healthcare organizations deliver safe, effective, high-quality care. They partner with executive teams and clinical leaders to align patient outcomes, operational priorities, and organizational goals.

What Does a Chief Clinical Officer Do?

A CCO provides senior-level oversight of clinical services and helps shape care delivery across a hospital, health system, medical group, or other healthcare organization. Responsibilities may include setting clinical standards, advancing quality and patient safety, supporting regulatory compliance, and using performance data to identify opportunities for improvement. CCOs often collaborate with physicians, nurses, administrators, and finance and operations teams.

Common CCO Responsibilities

  • Develop and implement clinical strategy aligned with organizational priorities.
  • Monitor quality, safety, patient experience, and clinical performance.
  • Lead initiatives that improve care coordination and clinical outcomes.
  • Support accreditation, regulatory readiness, and evidence-based practice.
  • Build alignment among medical staff, care teams, and executive leadership.
  • Guide clinical operations, resource planning, and service-line development.

Qualifications for Chief Clinical Officer Roles

Requirements vary by employer and setting. Many CCO positions call for a clinical degree and an active or previously held professional license, along with substantial experience in healthcare leadership. Employers may seek a physician executive or another experienced clinical leader with a record of improving quality, leading multidisciplinary teams, and managing complex organizational change. Business, health administration, or leadership training can also be valuable.

Find Chief Clinical Officer Jobs

CCO opportunities may be available at hospitals, health systems, specialty-care organizations, and other healthcare providers. Browse vetted Chief Clinical Officer openings on Ladders and explore senior healthcare leadership roles with compensation of $100,000 or more. Compare responsibilities and qualifications to identify positions that fit your experience and career goals.

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$85K - $100K *

Manage operational leadership for Care Coordination, overseeing staff, workflows, and patient advocacy. Collaborate with interdisciplinary teams to enhance care progression, resource utilization, and...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$333K - $416K *

Advance global clinical development efforts for neuropsychiatric disorders, overseeing study design, execution, and interpretation. Build relationships within the medical community and ensure complian...

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$333K - $416K *

Engineer and lead clinical development plans for neuropsychiatric disorders. Drive the execution of clinical studies and foster relationships with key stakeholders while ensuring compliance with regul...

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$333K - $416K *

Join a team that's committed to advancing clinical development for neuropsychiatric disorders and rare diseases. Contribute your extensive clinical expertise, develop robust study plans, and foster re...

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$115K - $172K *

Advance critical care services by providing strategic leadership and fostering team growth. Oversee departmental operations, ensure high-quality patient care, and drive quality improvement initiatives...

3 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Transform patient care by leading dialysis operations across multiple facilities. Collaborate with nursing teams to ensure compliance, quality outcomes, and staff development while providing clinical...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$270K - $280K *

Join a team that's driving clinical excellence by overseeing trial execution, managing timelines, budgets, and CROs. Collaborate with stakeholders to ensure compliance and quality while mentoring team...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$70K - $99K *

Support clinic operations by ensuring compliance, fostering community ties, and managing resources. Lead quality care initiatives and maintain financial integrity while coaching staff and enhancing pa...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$170K - $200K *

Elevate your career by leading enterprise-wide analytics and decision support. Collaborate with cross-functional leaders to enhance financial planning, operational effectiveness, and strategic insight...

4 days ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$135K - $160K *

Lead the charge in architecting and implementing complex application solutions, ensuring seamless integration and alignment with enterprise standards while driving enhancements and supporting technica...

2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$135K - $160K *

Drive the integration of complex application solutions, collaborating with cross-functional teams to enhance efficiency and resolve issues, while providing expert guidance in a consultative role to en...

Chicago, ILRemote

2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$90K - $95K *

Manage and oversee clinical support teams, ensuring adherence to policies, optimizing training outcomes, and maintaining high-quality client care while fostering effective communication across departm...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$247K - $322K *

Lead the charge in advancing clinical operations for late-stage cardiovascular studies. Oversee cross-functional teams, manage budgets, and drive innovative strategies to enhance patient outcomes and...

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$275K - $293K *

Drive strategic initiatives and operational excellence as a key partner to the CEO, optimizing internal processes and supporting growth in the neurological care sector. Collaborate across teams to enh...

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$238K - $315K *

Reimagine clinical trial safety leadership by establishing scalable operations and governance. Collaborate across teams to ensure data quality and compliance while driving innovation in patient safety...

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$103K - $114K *

Lead the development and management of medication-assisted treatment services, ensuring effective collaboration among healthcare teams. Drive program expansion, oversee clinical operations, and suppor...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Empower exceptional nursing leadership by overseeing clinical operations, ensuring quality patient care, and fostering collaboration among teams. Drive strategic initiatives and uphold regulatory stan...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$270K - $298K *

Empower your career by providing comprehensive primary healthcare services. Collaborate with a dedicated team to ensure quality patient care, perform assessments, and manage treatment plans in a dynam...

2 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$88K - $105K *

Transform healthcare IT by designing, implementing, and supporting software applications. Collaborate with teams to enhance user experience and optimize workflows, ensuring efficient operations and hi...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$170K - $200K *

Lead strategic planning and performance initiatives for network design and provider partnerships. Collaborate with cross-functional teams to optimize operations and drive affordability, ensuring align...

5 days ago

  •   8 - 10 years exp.  •   Healthcare

$170K - $200K *

Champion strategic network design and optimization initiatives, collaborating with leaders to drive affordability and enhance provider partnerships. Lead a high-performing team to execute multi-year r...

5 days ago

  •   8 - 10 years exp.  •   Healthcare

$170K - $200K *

Strategize and drive multi-year network design and optimization roadmaps, collaborating with leaders to enhance provider partnerships and affordability initiatives while leading high-performing teams...

5 days ago

  •   8 - 10 years exp.  •   Healthcare

$170K - $200K *

Lead the charge in developing and executing strategic roadmaps for network design and provider partnerships, driving affordability initiatives and operational excellence across multiple business lines...

5 days ago

  •   8 - 10 years exp.  •   Healthcare

$160K - $190K *

Champion strategic initiatives by driving network design and optimization. Collaborate with leaders to execute multi-year roadmaps, enhance provider partnerships, and identify affordability opportunit...

5 days ago

  •   8 - 10 years exp.  •   Healthcare

$170K - $200K *

Pioneer strategic initiatives in network design and provider partnerships. Collaborate with leaders to execute multi-year roadmaps, drive affordability, and enhance operational excellence across diver...

5 days ago

  •   8 - 10 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What is a Chief Clinical Officer?question toggle

    A Chief Clinical Officer is an executive who oversees clinical strategy and helps ensure that an organization delivers safe, effective, high-quality care. The role often connects clinical teams with executive leadership.

  • What does a Chief Clinical Officer do?question toggle

    A CCO commonly leads clinical quality and safety initiatives, sets care standards, supports regulatory compliance, reviews performance data, and works with clinical and operational leaders to improve care delivery.

  • What qualifications are usually required for CCO jobs?question toggle

    Requirements depend on the organization. Employers often look for a clinical degree, relevant licensure or clinical background, and extensive leadership experience in healthcare. Some roles favor physician executives or candidates with experience in health administration.

  • Where do Chief Clinical Officers work?question toggle

    Chief Clinical Officers may work for hospitals, health systems, medical groups, specialty-care providers, and other healthcare organizations with complex clinical operations.

  • How can I find Chief Clinical Officer jobs paying $100,000 or more?question toggle

    Browse Ladders for vetted senior healthcare leadership opportunities, review each listing’s requirements and compensation details, and focus your search on roles that match your clinical and executive experience.