Chief Clinical Officer (CCO) Jobs

Explore Chief Clinical Officer jobs on Ladders, where professionals can find vetted opportunities paying $100,000 or more. Chief Clinical Officers guide clinical strategy and help healthcare organizations deliver safe, effective, high-quality care. They partner with executive teams and clinical leaders to align patient outcomes, operational priorities, and organizational goals.

What Does a Chief Clinical Officer Do?

A CCO provides senior-level oversight of clinical services and helps shape care delivery across a hospital, health system, medical group, or other healthcare organization. Responsibilities may include setting clinical standards, advancing quality and patient safety, supporting regulatory compliance, and using performance data to identify opportunities for improvement. CCOs often collaborate with physicians, nurses, administrators, and finance and operations teams.

Common CCO Responsibilities

  • Develop and implement clinical strategy aligned with organizational priorities.
  • Monitor quality, safety, patient experience, and clinical performance.
  • Lead initiatives that improve care coordination and clinical outcomes.
  • Support accreditation, regulatory readiness, and evidence-based practice.
  • Build alignment among medical staff, care teams, and executive leadership.
  • Guide clinical operations, resource planning, and service-line development.

Qualifications for Chief Clinical Officer Roles

Requirements vary by employer and setting. Many CCO positions call for a clinical degree and an active or previously held professional license, along with substantial experience in healthcare leadership. Employers may seek a physician executive or another experienced clinical leader with a record of improving quality, leading multidisciplinary teams, and managing complex organizational change. Business, health administration, or leadership training can also be valuable.

Find Chief Clinical Officer Jobs

CCO opportunities may be available at hospitals, health systems, specialty-care organizations, and other healthcare providers. Browse vetted Chief Clinical Officer openings on Ladders and explore senior healthcare leadership roles with compensation of $100,000 or more. Compare responsibilities and qualifications to identify positions that fit your experience and career goals.

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$118K - $165K *

Join a dynamic team to oversee pharmacy operations, ensuring safe medication practices and quality patient care. Collaborate with healthcare professionals to enhance medication therapy management and...

2 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$118K - $165K *

Join a team that's dedicated to enhancing patient care through effective medication management and quality initiatives. Oversee pharmacy operations, ensuring compliance with best practices and regulat...

2 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$130K - $160K *

Shape the future of biomedical services by overseeing compliance, managing teams, and enhancing operational efficiency. Lead initiatives to improve client satisfaction and ensure the effective mainten...

2 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$300K *

Lead the charge in shaping integrated care models as a senior physician strategist. Oversee administrative functions for medical directors, ensuring quality, compliance, and the execution of a holisti...

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$333K - $450K *

Lead the charge in developing innovative clinical strategies to enhance patient safety and streamline Phase 2/3 programs, while collaborating with discovery teams and ensuring regulatory compliance in...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$333K - $450K *

Drive innovative clinical strategies to enhance development cycles and ensure patient safety. Collaborate with teams to design robust Phase 2/3 programs and lead Phase 1 testing, while managing extern...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$333K - $450K *

Partner with us to develop innovative clinical strategies that enhance patient safety and streamline Phase 2/3 programs, while collaborating with discovery teams and external stakeholders to drive imp...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$183K - $229K *

Drive operational excellence as a senior leader, overseeing market performance, managing physician and payer partnerships, and executing strategic plans to achieve financial and clinical targets in a...

Ohio, USRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$120K - $150K *

Join a team that's redefining healthcare leadership as a Chief Nursing Officer, where you'll drive patient care excellence, foster a collaborative culture, and lead nursing initiatives to achieve outs...

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $150K *

Lead nursing excellence by developing patient care programs, fostering collaboration, and ensuring compliance with healthcare standards. Empower teams to achieve superior outcomes while promoting a cu...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $150K *

Unlock potential by leading nursing excellence, fostering collaboration, and enhancing patient care through innovative programs and policies. Drive a culture of accountability and inclusivity while en...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $150K *

Lead the charge in transformative nursing leadership, enhancing patient care and outcomes in a dynamic healthcare environment. Collaborate with diverse teams to foster a culture of excellence and comp...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $150K *

Drive transformative nursing leadership in a dynamic healthcare environment, enhancing patient care and outcomes. Collaborate across disciplines to foster a team-oriented culture while ensuring compli...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Lead the charge in transforming patient care by developing innovative programs, guiding nursing staff, and collaborating with health professionals to enhance service quality and patient outcomes acros...

Westbury, NYIn-Person

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Lead nursing excellence by fostering collaboration across disciplines, developing innovative patient care solutions, and ensuring compliance with healthcare standards, all while inspiring a diverse te...

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K *

Join a team that's dedicated to enhancing resident care by leading nursing operations, ensuring compliance with health regulations, and fostering a supportive environment for staff development and qua...

Toronto, ONIn-Person

2 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$73K - $110K *

Join a team that's dedicated to delivering high-quality, patient-centered care while overseeing clinical operations and mentoring nursing staff in a dynamic healthcare environment focused on excellenc...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$210K - $250K *

Accelerate progress at a dynamic healthcare network by providing executive leadership and operational oversight, driving performance, and fostering a culture of collaboration to enhance patient care a...

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$180K - $220K *

Help us build a new clinical research site, providing medical oversight and leadership. Engage in innovative trials while shaping community health and advancing medical research, all within a supporti...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Empower your career by leading the establishment of a new clinical research site. As a Principal Investigator, you'll provide medical oversight, shape research initiatives, and engage with the communi...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$160K - $200K *

Join a team that's building a new clinical research site from the ground up. As a Principal Investigator, you'll provide medical oversight, shape research initiatives, and engage with the community wh...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Drive the establishment of a new clinical research site, providing medical oversight and leadership for trials. Engage with the community, ensuring participant safety and data quality while contributi...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Build a new clinical research site by providing medical oversight and leadership. Partner with a dedicated team to ensure participant safety and data quality while advancing innovative therapies in a...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Join a team that's dedicated to enhancing health care quality through innovative program development, compliance monitoring, and leadership in stroke care coordination. Engage with healthcare professi...

Reposted 5 days ago

  •   Less than 5 years exp.  •   Healthcare

$179K - $238K *

Empower clinical excellence by leading operations, education, and supply chain initiatives. Collaborate with executive leadership to standardize practices, enhance patient safety, and drive quality ou...

2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

Frequently Asked Questions (FAQ)

  • What is a Chief Clinical Officer?question toggle

    A Chief Clinical Officer is an executive who oversees clinical strategy and helps ensure that an organization delivers safe, effective, high-quality care. The role often connects clinical teams with executive leadership.

  • What does a Chief Clinical Officer do?question toggle

    A CCO commonly leads clinical quality and safety initiatives, sets care standards, supports regulatory compliance, reviews performance data, and works with clinical and operational leaders to improve care delivery.

  • What qualifications are usually required for CCO jobs?question toggle

    Requirements depend on the organization. Employers often look for a clinical degree, relevant licensure or clinical background, and extensive leadership experience in healthcare. Some roles favor physician executives or candidates with experience in health administration.

  • Where do Chief Clinical Officers work?question toggle

    Chief Clinical Officers may work for hospitals, health systems, medical groups, specialty-care providers, and other healthcare organizations with complex clinical operations.

  • How can I find Chief Clinical Officer jobs paying $100,000 or more?question toggle

    Browse Ladders for vetted senior healthcare leadership opportunities, review each listing’s requirements and compensation details, and focus your search on roles that match your clinical and executive experience.