Chief Clinical Officer (CCO) Jobs

Explore Chief Clinical Officer jobs on Ladders, where professionals can find vetted opportunities paying $100,000 or more. Chief Clinical Officers guide clinical strategy and help healthcare organizations deliver safe, effective, high-quality care. They partner with executive teams and clinical leaders to align patient outcomes, operational priorities, and organizational goals.

What Does a Chief Clinical Officer Do?

A CCO provides senior-level oversight of clinical services and helps shape care delivery across a hospital, health system, medical group, or other healthcare organization. Responsibilities may include setting clinical standards, advancing quality and patient safety, supporting regulatory compliance, and using performance data to identify opportunities for improvement. CCOs often collaborate with physicians, nurses, administrators, and finance and operations teams.

Common CCO Responsibilities

  • Develop and implement clinical strategy aligned with organizational priorities.
  • Monitor quality, safety, patient experience, and clinical performance.
  • Lead initiatives that improve care coordination and clinical outcomes.
  • Support accreditation, regulatory readiness, and evidence-based practice.
  • Build alignment among medical staff, care teams, and executive leadership.
  • Guide clinical operations, resource planning, and service-line development.

Qualifications for Chief Clinical Officer Roles

Requirements vary by employer and setting. Many CCO positions call for a clinical degree and an active or previously held professional license, along with substantial experience in healthcare leadership. Employers may seek a physician executive or another experienced clinical leader with a record of improving quality, leading multidisciplinary teams, and managing complex organizational change. Business, health administration, or leadership training can also be valuable.

Find Chief Clinical Officer Jobs

CCO opportunities may be available at hospitals, health systems, specialty-care organizations, and other healthcare providers. Browse vetted Chief Clinical Officer openings on Ladders and explore senior healthcare leadership roles with compensation of $100,000 or more. Compare responsibilities and qualifications to identify positions that fit your experience and career goals.

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$80K - $95K *

Transform patient care services by leading a dedicated team, ensuring high-quality outcomes, and fostering collaboration across departments to enhance operational efficiency and patient experience...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Transform your career by leading clinical laboratory operations, ensuring compliance, quality control, and staff development while collaborating with hospital leadership to enhance patient care and de...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$108K - $241K *

Manage innovative multi-site research initiatives, overseeing operations from proposal to completion. Collaborate with top investigators to enhance scientific discovery and patient care through effect...

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Join a visionary team to lead operational excellence in clinical education, driving performance and innovation within a dynamic network. Shape the future of graduate medical education while prioritizi...

Reposted today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$95K - $130K *

Lead the charge in clinical trial monitoring, ensuring compliance and quality through oversight, guidance, and collaboration with cross-functional teams to enhance site performance and study execution...

Boston, MARemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$115K - $135K *

Shape the future of clinical trials by leading site monitoring efforts, ensuring compliance, and fostering collaboration across teams. Drive quality and efficiency in trial execution while mentoring j...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $130K *

Elevate clinical trial success by overseeing site monitoring, ensuring compliance, and providing leadership. Collaborate with cross-functional teams to address site issues, enhance recruitment, and ma...

Boston, MARemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $130K *

Accelerate clinical trial success by leading site monitoring efforts, ensuring compliance, and providing expert guidance to the CRA team. Collaborate cross-functionally to resolve issues and enhance s...

Boston, MARemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Lead clinical trial monitoring efforts, ensuring compliance and quality. Collaborate with cross-functional teams to address site issues, manage budgets, and provide oversight. Drive successful study e...

Boston, MARemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$135K - $160K *

Lead the charge in enhancing nursing excellence by overseeing clinical operations, implementing strategic care initiatives, and ensuring compliance with healthcare regulations while driving performanc...

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$186K - $279K *

Drive the scientific foundation for trustworthy clinical AI systems, leading research and evaluation methodologies. Collaborate with cross-functional teams to ensure scalable, regulated practices that...

2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Unlock your potential by leading impactful healthcare research projects. Collaborate with clients and teams to derive actionable insights from qualitative and quantitative data, driving strategic deci...

Yesterday

  •   Less than 5 years exp.  •   Business Services

$159K - $273K *

Lead the charge in transforming healthcare technology by aligning strategy, operations, and innovation. Collaborate with executives to enhance clinical and operational performance while ensuring relia...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$248K - $341K *

Provide clinical development leadership for multiple programs, enhancing communication and collaboration across functions. Contribute to strategy, oversee trials, present findings, and mentor team mem...

4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$248K - $341K *

Lead clinical development initiatives across multiple studies, driving collaboration and innovative strategies. Shape and execute clinical trial objectives while fostering relationships with key stake...

Waltham, MARemote

4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$66K - $109K *

Lead the coordination of surgical operations, ensuring optimal staffing, equipment management, and patient care. Collaborate with interdisciplinary teams to enhance patient experiences and uphold regu...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$176K - $220K *

Transform clinical development with strategic leadership to execute Phase 3 trials. Drive operational excellence, manage cross-functional collaboration, and shape innovative processes to elevate globa...

3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$93K - $101K *

Empower our community by leading Mission Integration and Pastoral Care initiatives, fostering spiritual growth, and providing compassionate support to residents, families, and staff while collaboratin...

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$66K - $99K *

Champion patient care by utilizing your nursing expertise to lead clinical teams, coordinate care, and mentor staff. Engage in effective communication and critical thinking to enhance patient outcomes...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Unlock potential by leading clinical services as a Medical Director, ensuring quality healthcare delivery in a correctional setting. Collaborate with staff and community providers to enhance patient c...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$149K - $224K *

Drive analytics excellence by leading a team to deliver impactful insights, enhance reporting capabilities, and support strategic decision-making across diverse business functions. Foster collaboratio...

United StatesRemote

Yesterday

  •   11 - 15 years exp.  •   Healthcare

$160K - $200K *

Transform service delivery by leading high-performance teams, ensuring client satisfaction, and driving strategic initiatives. Collaborate across departments to enhance practice management and achieve...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Healthcare

$165K - $200K *

Innovate patient care by enhancing experiences across all touchpoints. Lead initiatives to gather feedback, design service standards, and resolve complaints, ensuring every patient feels valued and he...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Lead the charge in delivering exceptional home health services by overseeing patient care, managing interdisciplinary teams, and ensuring compliance with regulations while fostering a supportive envir...

Reposted today

  •   Less than 5 years exp.  •   Healthcare

$231K - $264K *

Unlock potential by leading strategic initiatives to enhance clinical operations, drive operational excellence, and foster collaboration across cross-functional teams while optimizing processes and re...

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What is a Chief Clinical Officer?question toggle

    A Chief Clinical Officer is an executive who oversees clinical strategy and helps ensure that an organization delivers safe, effective, high-quality care. The role often connects clinical teams with executive leadership.

  • What does a Chief Clinical Officer do?question toggle

    A CCO commonly leads clinical quality and safety initiatives, sets care standards, supports regulatory compliance, reviews performance data, and works with clinical and operational leaders to improve care delivery.

  • What qualifications are usually required for CCO jobs?question toggle

    Requirements depend on the organization. Employers often look for a clinical degree, relevant licensure or clinical background, and extensive leadership experience in healthcare. Some roles favor physician executives or candidates with experience in health administration.

  • Where do Chief Clinical Officers work?question toggle

    Chief Clinical Officers may work for hospitals, health systems, medical groups, specialty-care providers, and other healthcare organizations with complex clinical operations.

  • How can I find Chief Clinical Officer jobs paying $100,000 or more?question toggle

    Browse Ladders for vetted senior healthcare leadership opportunities, review each listing’s requirements and compensation details, and focus your search on roles that match your clinical and executive experience.