Chief Clinical Officer (CCO) Jobs

Explore Chief Clinical Officer jobs on Ladders, where professionals can find vetted opportunities paying $100,000 or more. Chief Clinical Officers guide clinical strategy and help healthcare organizations deliver safe, effective, high-quality care. They partner with executive teams and clinical leaders to align patient outcomes, operational priorities, and organizational goals.

What Does a Chief Clinical Officer Do?

A CCO provides senior-level oversight of clinical services and helps shape care delivery across a hospital, health system, medical group, or other healthcare organization. Responsibilities may include setting clinical standards, advancing quality and patient safety, supporting regulatory compliance, and using performance data to identify opportunities for improvement. CCOs often collaborate with physicians, nurses, administrators, and finance and operations teams.

Common CCO Responsibilities

  • Develop and implement clinical strategy aligned with organizational priorities.
  • Monitor quality, safety, patient experience, and clinical performance.
  • Lead initiatives that improve care coordination and clinical outcomes.
  • Support accreditation, regulatory readiness, and evidence-based practice.
  • Build alignment among medical staff, care teams, and executive leadership.
  • Guide clinical operations, resource planning, and service-line development.

Qualifications for Chief Clinical Officer Roles

Requirements vary by employer and setting. Many CCO positions call for a clinical degree and an active or previously held professional license, along with substantial experience in healthcare leadership. Employers may seek a physician executive or another experienced clinical leader with a record of improving quality, leading multidisciplinary teams, and managing complex organizational change. Business, health administration, or leadership training can also be valuable.

Find Chief Clinical Officer Jobs

CCO opportunities may be available at hospitals, health systems, specialty-care organizations, and other healthcare providers. Browse vetted Chief Clinical Officer openings on Ladders and explore senior healthcare leadership roles with compensation of $100,000 or more. Compare responsibilities and qualifications to identify positions that fit your experience and career goals.

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$143K - $258K *

Transform operational performance by leading continuous value improvement initiatives. Drive strategic analysis, identify risks, and enhance decision-making processes to ensure impactful outcomes acro...

6 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$80K - $100K *

Manage and enhance clinical operations, supporting quality assurance and building strong relationships between hospital staff, PCPs, and patients. Drive performance improvement through data analysis a...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$143K - $258K *

Lead the charge in enhancing operational performance through strategic analysis, risk assessment, and performance management. Drive impactful decision-making by translating complex data into actionabl...

6 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$140K - $160K *

Drive operational excellence and strategic growth in behavioral health services, ensuring patient-centered care and compliance. Collaborate with leadership to enhance quality, access, and financial pe...

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$60K - $99K *

Empower individuals by providing comprehensive HIV and STI screening, education, and care coordination. Utilize trauma-informed approaches to enhance client engagement and support access to essential...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$160K - $200K *

Join an elite team to co-lead a premier military health research center, driving strategic innovation and excellence in healthcare research operations while collaborating with national partners on imp...

Toronto, ONIn-Person

Reposted 5 days ago

  •   11 - 15 years exp.  •   Hospitals & Medical Centers

$256K - $288K *

Play a key role in clinical trial oversight, design, and execution while collaborating with cross-functional teams to ensure data integrity and regulatory compliance in support of our innovative thera...

4 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$256K - $288K *

Lead the charge in clinical trial oversight and data interpretation, ensuring safety and efficacy of pipeline products through expert collaboration and strategic planning, aligning clinical activities...

Waltham, MARemote

4 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Elevate healthcare quality by leading performance improvement initiatives across multiple states. Collaborate with executives and teams to enhance patient safety, regulatory compliance, and organizati...

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Elevate your career by leading clinical education initiatives that enhance training programs and ensure high-quality patient care through collaboration and evidence-based practices...

Loveland, OHRemote

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$283K - $325K *

Lead the charge in clinical compliance strategy, ensuring operational readiness and inspection preparedness across early and late-phase clinical development programs. Collaborate with cross-functional...

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$175K - $199K *

Deliver strategic oversight and enhance services in Intake and Clinical departments, directly impacting employee morale and development while ensuring high-quality consumer service and operational eff...

3 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$125K - $150K *

Join a dynamic team to oversee patient-centered care, ensuring quality outcomes and compliance while fostering collaboration and accountability across departments. Drive strategic initiatives to enhan...

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Lead the charge in delivering exceptional home health services by supervising patient care, managing interdisciplinary teams, and ensuring compliance with regulatory standards while fostering a suppor...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$102K - $160K *

Take ownership of the medical staff services department, ensuring compliance, education, and operational excellence while fostering collaboration between medical and executive leadership to enhance pa...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$225K - $240K *

Architect innovative clinical strategies and collaborate with cross-functional teams to drive the execution and analysis of clinical studies, ensuring high-quality data delivery and alignment with dev...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$200K - $225K *

Create a transformative vision for programs in emergency shelter and supportive housing. Collaborate with leadership to innovate, scale successful initiatives, and enhance organizational impact while...

2 weeks ago

  •   11 - 15 years exp.  •   Education, Government & Non-Profit

$123K - $185K *

Unlock your leadership potential by overseeing emergency services, ensuring high-quality patient care, and fostering a culture of collaboration and accountability. Drive strategic initiatives, manage...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$108K - $130K *

Oversee high-quality, patient-centered emergency services by managing staffing, budgeting, and compliance. Foster collaboration and implement strategies to enhance care quality, patient experience, an...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Transform healthcare delivery by leading the development of an integrated virtual metabolic health clinic, optimizing provider interactions, and enhancing patient care experiences across multiple disc...

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$80K - $95K *

Drive your career forward by leading nursing operations in a dynamic post-acute rehab unit. Oversee daily activities, ensure quality care, and foster a collaborative environment while enjoying competi...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$198K - $297K *

Join a team that's redefining encounter data management, leading strategy and operations to ensure accurate Part C and Part D submissions. Drive cross-functional collaboration and enhance data governa...

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Advance your career by overseeing clinical operations and enhancing practice efficiency. Collaborate with leadership to implement strategic initiatives, mentor managers, and drive high-quality service...

2 days ago

  •   8 - 10 years exp.  •   Healthcare

$180K - $220K *

Lead the charge in delivering quality patient-centered care as the Medical Director for a new primary care clinic, overseeing clinical operations, education, and resident supervision in a collaborativ...

Reposted yesterday

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$160K - $200K *

Empower your career by leading operational excellence in healthcare. As a key player in the COO Program, you’ll gain invaluable experience influencing patient care and driving strategic initiatives ac...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What is a Chief Clinical Officer?question toggle

    A Chief Clinical Officer is an executive who oversees clinical strategy and helps ensure that an organization delivers safe, effective, high-quality care. The role often connects clinical teams with executive leadership.

  • What does a Chief Clinical Officer do?question toggle

    A CCO commonly leads clinical quality and safety initiatives, sets care standards, supports regulatory compliance, reviews performance data, and works with clinical and operational leaders to improve care delivery.

  • What qualifications are usually required for CCO jobs?question toggle

    Requirements depend on the organization. Employers often look for a clinical degree, relevant licensure or clinical background, and extensive leadership experience in healthcare. Some roles favor physician executives or candidates with experience in health administration.

  • Where do Chief Clinical Officers work?question toggle

    Chief Clinical Officers may work for hospitals, health systems, medical groups, specialty-care providers, and other healthcare organizations with complex clinical operations.

  • How can I find Chief Clinical Officer jobs paying $100,000 or more?question toggle

    Browse Ladders for vetted senior healthcare leadership opportunities, review each listing’s requirements and compensation details, and focus your search on roles that match your clinical and executive experience.