Welcome to Principal Scientist Jobs

Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.

Why Principal Scientist Jobs?

As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.

Our Offerings

We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.

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1
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$151K - $261K *

Elevate NGS diagnostic innovation by leading algorithm development to enhance clinical outcomes. Drive analytical validation, regulatory readiness, and algorithm performance in oncology, focusing on s...

US-AnywhereRemote

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$175K - $230K *

Elevate drug substance development by leading process innovation and CDMO partnerships. Drive projects from early development through commercialization, ensuring regulatory compliance and strategic al...

US-AnywhereRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$175K - $230K *

Lead the charge in shaping AI products for a resilient global supply chain. Drive strategies, governance, and scalable AI delivery while partnering across teams to enhance data readiness and operation...

US-AnywhereRemote

2 days ago

  •   11 - 15 years exp.  •   Enterprise Technology

$175K - $230K *

Lead the strategy and implementation of AI-driven products leveraging large language models to enhance supply chain efficiency. Collaborate with cross-functional teams to ensure data readiness and dri...

US-AnywhereRemote

2 days ago

  •   11 - 15 years exp.  •   Enterprise Technology

$125K - $224K *

Contribute to groundbreaking research by enhancing atmospheric radiative transfer models, collaborating with a team of experts, and driving innovation in numerical methods within the scientific commun...

US-AnywhereRemote

1 week ago

  •   15+ years exp.  •   Aerospace & Defense

$171K - $214K *

Join a pioneering oncology research team to lead translational projects, integrating cutting-edge single-cell and spatial biology technologies to enhance drug discovery and clinical applications acros...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$175K - $230K *

Drive your career with innovative AI and machine learning products that enhance global supply chain efficiency. Own strategy, elevate data standards, lead governance, and foster collaboration in a sen...

US-AnywhereRemote

Today

  •   11 - 15 years exp.  •   Information Technology

$120K - $150K *

Transform the future of drug development by leading innovative simulation projects, acting as a scientific liaison between clients and teams, and driving advances in pharmacometrics with your expertis...

US-AnywhereRemote

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$100K - $130K *

Accelerate progress at the forefront of clinical research by designing and conducting studies that enhance our understanding of new therapies, while collaborating with multidisciplinary teams and appl...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $135K *

Advance your career by leading complex AI and IT projects. This high-visibility role entails managing cross-functional teams and driving accountability across multiple workstreams, ensuring successful...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$234K - $271K *

Lead the charge in developing cutting-edge AI and image processing solutions for cardiac imaging, translating clinical needs into innovative algorithms while collaborating across functions to enhance...

US-AnywhereRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $170K *

Accelerate progress at leading innovative projects while driving business growth and team success through strategic leadership, client engagement, and operational excellence in the biomanufacturing se...

US-AnywhereRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$165K - $206K *

Lead the charge in transforming complex data into actionable insights, partnering with stakeholders to measure and optimize commercial strategies, and architecting large datasets to influence critical...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$173K - $277K *

Innovate within the AI Center of Excellence to architect and govern advanced AI solutions, shaping how AI is designed, deployed, and scaled across all engineering projects with a commitment to excelle...

US-AnywhereRemote

3 days ago

  •   8 - 10 years exp.  •   Information Technology

$152K - $190K *

Join a team that's shaping the future of healthcare through innovative software solutions. As a technical leader, you'll drive the design and development of next-gen clinical data platforms while ment...

US-AnywhereRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Healthcare

$150K - $180K *

Lead impactful client engagements by managing complex drug substance and product development programs. Drive success through cross-functional teamwork, strategic oversight, and proactive client relati...

US-AnywhereRemote

Reposted 3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$90K - $120K *

Advance pharmaceutical marketing analytics by leading insight delivery and measurement strategies. Oversee KPI frameworks, reporting processes, and data visualization to ensure compelling insights tha...

US-AnywhereRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $130K *

Join a team that's leading innovative Cost Improvement Projects in medical devices. You'll manage engineering efforts, ensuring compliance while driving change and collaboration across cross-functiona...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $120K *

Lead strategic governance and performance oversight across global laboratory networks, fostering effective partnerships and ensuring compliance to enhance service delivery and business success. Drive...

US-AnywhereRemote

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $200K *

Drive the advancement of our predictive toxicology platform. Collaborate cross-functionally to shape scientific vision, develop innovative modeling techniques, and oversee execution. Lead a diverse te...

US-AnywhereRemote

Reposted yesterday

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$90K *

Take ownership of project operations, ensuring quality execution and client satisfaction through effective management of timelines, budgets, stakeholder relationships, and study logistics while leadin...

US-AnywhereRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$122K *

Champion project success by leading the global team in Oncology, ensuring adherence to budgets, timelines, and quality standards while fostering client relationships and supporting business developmen...

US-AnywhereRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$118K - $197K *

Shape the future of animal health by leading regulatory strategies for innovative veterinary products. Collaborate globally, engage with regulatory agencies, and drive project success through expert n...

US-AnywhereRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$152K - $180K *

Shape the future of genomics by leading statistical genetics analyses that drive insights, support research programs, and facilitate impactful collaborations across teams. Leverage cutting-edge method...

US-AnywhereRemote

4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$140K - $180K *

Elevate your career by leading strategic marketing initiatives that drive growth, enhance client engagement, and foster collaboration across teams. leverage your expertise in a dynamic role that shape...

US-AnywhereRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What is the role of a Principal Scientist?question toggle

    A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.

  • How much does a Principal Scientist earn on average?question toggle

    The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.

  • What qualifications are required for Principal Scientist jobs?question toggle

    Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.

  • Can I find remote Principal Scientist jobs on Ladders?question toggle

    Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.