Explore $100K+ Jobs in Oklahoma

Find professional opportunities across Oklahoma with salaries of $100,000 or more. Ladders features vetted jobs for experienced candidates seeking leadership, specialized, and other high-paying roles. Explore openings in Oklahoma City, Tulsa, and communities throughout the state, and discover opportunities that match your skills and career goals.

High-Paying Careers Across Oklahoma

Oklahoma’s economy includes established industries such as energy, aerospace, healthcare, manufacturing, finance, and technology. Employers may seek experienced professionals for roles in operations, engineering, corporate leadership, sales, information technology, and clinical or administrative management. Available positions and compensation vary by employer, location, experience, and specialization.

Find the Right Role for Your Experience

Use Ladders to explore vetted professional job listings and focus your search on roles with compensation of $100,000 or more. Review each posting for its responsibilities, qualifications, location, and compensation details. Set up a strong profile and tailor your resume to highlight measurable results, relevant expertise, and leadership experience.

Search Oklahoma Jobs on Ladders

Whether you’re considering a move to Oklahoma or looking to advance your career close to home, browse current high-paying opportunities and apply to positions that fit your background. New listings may appear as employers’ needs change, so check back regularly for the latest Oklahoma jobs.

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$120K - $145K *

Join a team that shapes global regulatory strategy in a fast-paced environment. You will lead comprehensive regulatory plans, ensuring alignment and execution from development to post-marketing, impac...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$130K - $150K *

Champion effective publication strategies and lead scientific communication initiatives, acting as a strategic partner to clients and teams. Navigate complex medical affairs content to drive impactful...

RemoteRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Lead the charge in ensuring compliance with federal and state regulations by developing, filing, and maintaining product forms. Collaborate with team members to meet project goals while mentoring juni...

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$250K - $286K *

Shape the future of sales by leading a dynamic team to drive new business, refine strategies, and enhance customer experiences in a fast-paced SaaS environment, while mentoring leaders and achieving a...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Contribute to the success of multiple clinical research sites by leading operations, ensuring compliance with regulations, and fostering team development to enhance patient care and operational excell...

United StatesRemote

Reposted 1 month ago

  •   5 - 7 years exp.  •   Healthcare

$176K - $243K *

Accelerate progress at the forefront of cardiovascular innovation, leading a dynamic team to drive the adoption of advanced imaging solutions in the U.S. market, while fostering strategic partnerships...

United StatesRemote

Reposted yesterday

  •   11 - 15 years exp.  •   Healthcare

$195K - $256K *

Elevate clinical quality assurance by designing and executing strategies for compliance, audit management, and oversight of global clinical operations. Collaborate with stakeholders to ensure adherenc...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$92K - $138K *

Deliver clinical expertise and training support for XR products, enhancing customer experience and operational efficiency. Collaborate with sales and clinical teams to drive education initiatives and...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Business Services

$160K - $200K *

Lead the charge in analytical development, overseeing drug substance and product strategies. Collaborate across teams to ensure compliance and performance, while mentoring a high-performing analytical...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$250K - $300K *

Champion innovative radiology practices to enhance patient care and operational efficiency alongside a dynamic team. Drive clinical excellence and leverage technology to elevate standards across healt...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Healthcare

$212K - $287K *

Transform the Hematology landscape by leading a high-performing sales team, driving strategic initiatives, and ensuring compliance while exceeding sales objectives in the Great Plains region...

RemoteRemote

2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$180K - $215K *

Shape the future of healthcare by leading regional sales efforts, driving product launch success, and building high-performing teams. Collaborate cross-functionally to achieve sales goals and foster s...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Unlock potential by leading Health and VA claims operations, driving strategic initiatives, enhancing recovery outcomes, and ensuring operational excellence across multiple teams and client portfolios...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$80K - $100K *

Join a team that's dedicated to delivering high-quality psychotherapy to older adults. Enjoy flexible scheduling, comprehensive support, and the opportunity to make a meaningful impact in a collaborat...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Unlock your potential as a senior Epic Willow Analyst, leading pharmacy workflow configurations and supporting clinical applications in a dynamic healthcare environment. Collaborate with teams to opti...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$180K - $215K *

Transform your career by leading regional sales efforts, driving product launch success, and building high-performing teams. Collaborate cross-functionally to achieve sales goals and foster strong cus...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$130K - $150K *

Champion clinical project success by leading operations, training teams, and ensuring compliance. Drive strategic planning and risk management while overseeing site performance and fostering collabora...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $110K *

Design and develop advanced analytics solutions, transforming complex healthcare data into actionable insights using Azure Databricks and Power BI. Collaborate with cross-functional teams to enhance r...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Join a team that's dedicated to delivering exceptional emergency care, managing diverse patient needs with autonomy in a fast-paced environment. Collaborate with offsite physicians while practicing at...

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$175K - $215K *

Launch impactful product initiatives by bridging engineering and design while driving user-centered solutions and leveraging AI tools for enhanced workflows in a high-growth environment...

RemoteRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$180K - $220K *

Lead the charge in developing clinical content strategies and overseeing teams within the market access practice. Drive innovation, enhance client strategies, and ensure high standards in service deli...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Join a team that's redefining telehealth by delivering exceptional psychotherapy to older adults. Enjoy flexible hours, comprehensive support, and opportunities for professional growth while making a...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$130K - $140K *

Empower healthcare providers by promoting innovative colorectal cancer screening solutions, delivering exceptional support and education while strategically expanding product adoption across a designa...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$75K - $87K *

Inspire exceptional psychiatric care by evaluating and managing mental health needs, providing education, and coordinating treatment as a vital member of the care team while supervising LPNs and HHAs...

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$215K - $240K *

Shape the future of commercial operations by leading strategy, workflows, and data integration. Collaborate with senior leaders to enhance brand performance and drive operational excellence across cro...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs can I find in Oklahoma?question toggle

    Listings may include professional and leadership roles in areas such as energy, aerospace, healthcare, technology, manufacturing, finance, engineering, operations, and sales. Job availability and compensation vary.

  • Which Oklahoma cities have high-paying job opportunities?question toggle

    Opportunities may be available in Oklahoma City, Tulsa, and other communities across the state. Check each listing for its location and whether remote or hybrid work is offered.

  • Does Ladders list jobs that pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with compensation of $100,000 or more. Review individual postings for specific salary information and qualifications.

  • How can I find Oklahoma jobs that fit my experience?question toggle

    Search current listings and compare each role’s requirements, responsibilities, location, and compensation. Tailor your resume to emphasize relevant skills, accomplishments, and experience.