Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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$80K - $100K *

Advance impactful medical communications by crafting precise, engaging content. Collaborate with cross-functional teams to ensure accuracy and alignment with client objectives while mentoring junior s...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$180K - $210K *

Lead the charge in transforming people analytics by applying causal inference and advanced statistical methods to drive strategic decisions on recruitment, retention, and compensation across the organ...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

$125K - $150K *

Champion growth by building strategic relationships and driving sales in the Healthcare sector. Leverage AI solutions to enhance customer engagement and achieve revenue targets while collaborating wit...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$100K - $120K *

Empower your veterinary career by providing urgent care for pets in a supportive, modern environment. Collaborate with a dedicated team to manage diverse cases while enjoying a flexible schedule and o...

4 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$165K - $215K *

Empower innovation in ophthalmic device development by leading global clinical strategies for surgical programs, from feasibility to regulatory submissions. Collaborate cross-functionally to drive pro...

RemoteRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Healthcare

$157K - $242K *

Join a team that's shaping groundbreaking hardware solutions by defining system architecture, integrating cross-functional requirements, and leading technical direction for complex, production-ready d...

United StatesRemote

Reposted 2 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$100K - $120K *

Transform healthcare delivery by providing emergency and primary care at remote worksites. Collaborate with clinical teams to ensure quality assurance and support field staff while maintaining essenti...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Join a team that's dedicated to ensuring compliance and quality in site contracts. Manage negotiations, oversee contract processes, and collaborate with clients and experts to deliver timely and effec...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Lead the charge in transforming complex revenue-cycle challenges into robust, production-ready AI models, ensuring statistical integrity and operational reliability while managing end-to-end data pipe...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Healthcare

$160K - $192K *

Accelerate commercial success by engaging healthcare providers and driving product adoption. Collaborate with cross-functional teams to optimize patient access and support innovative therapies in a dy...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Transform your career by enhancing data security and integrity. Collaborate with cross-functional teams to implement robust security measures, conduct audits, and mitigate risks while staying ahead of...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Take ownership of medication therapy management services, conducting comprehensive reviews and consultations. Collaborate with the MTM product team to ensure accurate data entry and enhance patient ca...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Information Technology

$136K - $220K *

Unlock project management excellence in Global Regulatory Affairs, driving timelines and compliance for drug submissions. Collaborate cross-functionally to ensure accurate documentation and effective...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Grow your career with an influential role in customer success, fostering strong relationships and driving client satisfaction post-sale while managing renewals and growth opportunities in the health c...

RemoteRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$125K - $150K *

Lead the Corporate FP&A function, overseeing forecast consolidation, monthly reporting, and financial analysis. Collaborate with finance and business partners to ensure accuracy and transparency in fi...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$142K - $177K *

Champion innovative risk adjustment solutions by leveraging deep expertise to enhance payer and provider strategies. Collaborate with cross-functional teams to deliver impactful presentations and driv...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$95K - $115K *

Elevate project delivery by leading cross-functional teams in Interactive Response Technology, ensuring client satisfaction and timely execution while managing risks and fostering continuous improveme...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$96K - $120K *

Partner with cross-functional teams to drive successful integrations, ensuring best practices and client satisfaction. Become the internal expert on data management while leading technical relationshi...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$170K - $200K *

Lead the charge in managing complex Life Sciences programs, ensuring alignment with customer commitments. Drive delivery across teams, proactively addressing risks and building a PMO as the business s...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $200K *

Transform clinical research by leading operational oversight of studies, ensuring compliance with protocols and regulations. Collaborate with teams to drive site feasibility, manage budgets, and enhan...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$110K - $200K *

Join a team that's dedicated to advancing clinical research by leading operational aspects of trials, ensuring compliance with protocols and regulations, and fostering collaboration among stakeholders...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$101K - $197K *

Empower your career by leading global regulatory strategies for medical devices and diagnostics. Collaborate with cross-functional teams to ensure compliance and drive market access while mentoring ot...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$160K - $192K *

Join a team that's driving commercial success by engaging healthcare providers, building relationships, and supporting innovative therapies. Your expertise will be crucial in executing business plans...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $120K *

Shape the future of Crop Protection & Chemicals by driving sales and fostering client relationships. Utilize strategic insights and collaboration to achieve targets and expand market presence while ma...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Unlock potential by leading pre-sales technical strategies that align solutions with client needs, driving revenue growth and retention through collaboration with sales teams and delivering tailored p...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.