Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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$210K - $253K *

Lead strategic partnerships to drive growth and success in a dynamic healthcare ecosystem. Collaborate with internal teams and external stakeholders to enhance relationships, execute activation plans...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $160K *

Join a team that's redefining data solutions by leading technical sales efforts, collaborating with Account Managers, and driving customer success through innovative data architecture and tailored dem...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$68K - $105K *

Unlock potential by configuring and supporting Epic Orders applications. Engage in business analysis, system design, and user support to enhance workflows and resolve issues, while managing projects a...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Shape the future of client success by leading implementations and driving adoption for enterprise accounts. Collaborate across teams to ensure measurable value and build scalable processes that enhanc...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Optimize internal tooling ecosystems to enhance operational efficiency. Collaborate with engineering to develop AI-driven solutions and automate workflows that streamline team processes and enable sca...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $230K *

Engage key stakeholders in oncology by promoting innovative products, building relationships, and driving access to care. Lead strategic initiatives to exceed performance goals while embodying corpora...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$206K - $268K *

Empower operational finance by leading cost-of-revenue functions, serving as a strategic partner to executives and enhancing organizational performance and scalability through effective leadership and...

United StatesRemote

Reposted 6 days ago

  •   11 - 15 years exp.  •   Healthcare

$211K - $235K *

Drive patient access initiatives by leveraging oncology expertise to navigate reimbursement landscapes, educate stakeholders, and resolve complex access issues, ensuring timely therapy access for pati...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$87K *

Advance your career by providing essential occupational therapy services under supervision. Collaborate with patients to enhance their functional independence while adhering to safety and compliance p...

Today

  •   Less than 5 years exp.  •   Staffing

$87K *

Join a team that's dedicated to enhancing patient independence through effective occupational therapy services, collaborating closely with licensed OTs to implement care plans and support patient prog...

Today

  •   Less than 5 years exp.  •   Staffing

$79K - $127K *

Drive your career forward by overseeing tax compliance and accounting functions. You'll conduct research, manage filings, and identify opportunities while ensuring adherence to evolving tax laws. Join...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$160K - $200K *

Drive the M&A strategy by leading the full transaction lifecycle, from sourcing to integration. Collaborate with executive leadership to identify growth opportunities that enhance enterprise value and...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$177K - $243K *

Advance your career by leading a global compensation function, shaping strategies, and building a high-performing team. Collaborate with key stakeholders to drive compensation programs that align with...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$59K - $108K *

Drive patient-centered care as a Float Staff Nurse, supporting diverse specialties across clinics. Collaborate with teams to enhance patient experiences and streamline care, ensuring comprehensive sup...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $235K *

Join a team that's redefining business processes through digital transformation. Lead cross-functional initiatives, ensuring scalable and standardized practices that align with strategic goals while f...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$134K - $184K *

Shape the future of customer success by leading a high-performing team, optimizing operations, and driving engagement and retention strategies to achieve key performance indicators and enhance client...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$114K - $187K *

Champion clinical laboratory operations by managing complex projects, ensuring timely study starts, and collaborating with cross-functional teams to deliver impactful results in precision medicine...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$149K - $224K *

Lead the charge in shaping digital solutions for perioperative workflows, driving strategy and execution across cross-functional teams to enhance clinical outcomes and operational efficiency in surgic...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$150K - $180K *

Innovate healthcare delivery by serving as a clinical liaison, translating partner needs into actionable insights for chronic care and telehealth programs, impacting thousands of patients nationwide t...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$85K - $100K *

Champion compliance excellence by reviewing retail communications to ensure adherence to regulations and firm policies. Collaborate with teams to maintain high standards and support organizational goa...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$124K - $135K *

Shape impactful training programs for Field Access teams, enhancing access and reimbursement capabilities across therapeutic areas. Collaborate with stakeholders to ensure compliance and relevance, fo...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Engage with us to elevate workplace design through innovative solutions. As a key contributor, you'll lead project documentation, collaborate with teams, and ensure design excellence while managing sc...

Yesterday

  •   5 - 7 years exp.  •   Real Estate & Construction

$110K - $159K *

Inspire excellence in clinical documentation by leading a team of specialists, ensuring quality assurance, and fostering professional development. Collaborate with stakeholders to enhance operational...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$110K - $159K *

Empower the Clinical Documentation Integrity team by ensuring staff competency through quality assurance, training, and performance management. Collaborate on action plans and foster associate develop...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$110K - $159K *

Lead the charge in enhancing clinical documentation integrity by supervising staff, conducting quality reviews, and fostering professional development. Collaborate with teams to implement effective st...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.