Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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$74K - $87K *

Unlock patient access by managing the insurance verification process, addressing barriers to care, and ensuring seamless coordination among stakeholders to facilitate timely therapy access and support...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$71K - $112K *

Drive impactful financial and operational analysis to enhance performance. Collaborate with stakeholders, mentor junior analysts, and present insights that inform strategic decisions across the organi...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Join a team that's dedicated to ensuring the quality and safety of clinical trials. As a Senior Clinical Research Associate, you'll manage site relationships, oversee monitoring activities, and contri...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $105K *

Unlock potential by supporting compensation programs through analysis, reporting, and administration. Collaborate with HR and finance teams to ensure accurate employee compensation data and streamline...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Join a dynamic team to develop and deliver clinical training programs, ensuring high-quality education for partners and stakeholders. Act as a subject-matter expert while fostering relationships to en...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$160K - $192K *

Grow your career by engaging healthcare providers and driving commercial success. Collaborate with cross-functional teams to support product launches and enhance patient access to innovative therapies...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$68K - $113K *

Lead the charge in optimizing coding accuracy and compliance by analyzing complex patient care documentation, providing expert guidance, and enhancing coder education to ensure adherence to ethical st...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Business Services

$150K - $224K *

Unlock potential by engaging with healthcare stakeholders to enhance patient outcomes through strategic medical insights and collaboration within the CNS ecosystem, driving effective utilization of Ot...

RemoteRemote

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Join a team that's advancing oncology solutions by managing global clinical trials. Lead project execution from protocol development to study closeout, ensuring quality and compliance while fostering...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$295K - $314K *

Drive strategic biostatistical leadership for clinical development programs, overseeing statistical activities, collaborating with cross-functional teams, and ensuring high-quality data analysis to su...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$90K - $110K *

Analyze and optimize workforce management strategies across multiple business lines, translating complex forecasts into actionable capacity plans and financial models while collaborating with executiv...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Join a dynamic finance team as you oversee financial reporting, manage reconciliations, and enhance accounting processes. Your expertise will ensure compliance with GAAP while supporting audits and op...

United StatesRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Healthcare

$78K - $104K *

Inspire efficient EHR system performance by leading applications analysis and optimization. Drive project management and collaboration while mentoring team members and enhancing patient care through e...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$180K - $220K *

Lead the sales strategy for a healthcare Payer business unit, driving market penetration, revenue growth, and client satisfaction. Collaborate with leadership to shape go-to-market strategies and buil...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Healthcare

$150K - $180K *

Champion a transformative product vision, leading cross-functional teams to drive strategic outcomes in a dynamic digital health environment. Shape the future of patient care and client experience whi...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$140K - $270K *

Lead the charge in transforming healthcare workflows with AI solutions, optimizing performance, and collaborating across teams to create scalable systems that enhance clinical and revenue outcomes...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$177K - $221K *

Manage the strategy and execution of access marketing for oncology products, focusing on value propositions for payers and healthcare providers. Collaborate with cross-functional teams to ensure effec...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Contribute to impactful consulting services in government pricing, leveraging your expertise to guide clients through compliance, data analysis, and strategic initiatives while leading a collaborative...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$192K - $288K *

Join us as a strategic partner in global clinical development operations, driving workforce planning, budget management, and continuous improvement initiatives. Collaborate with leadership to enhance...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$170K - $200K *

Empower a high-growth organization by leading operations strategy, enhancing client satisfaction, and driving efficiency through AI and automation. Collaborate with senior leadership to ensure financi...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$85K - $100K *

Join a team that's focused on driving financial accuracy while managing month-end closes, reconciliations, and cost accounting. Contribute to board-level reporting in a dynamic PE-backed SaaS environm...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $100K *

Join a team that's dedicated to managing regulatory and audit processes, ensuring compliance and operational readiness. As a Senior Analyst, you'll coordinate responses, conduct analysis, and enhance...

Yesterday

  •   Less than 5 years exp.  •   Finance & Insurance

$118K - $196K *

Lead the charge in developing and executing drug formulary strategies, ensuring compliance with regulations while collaborating with cross-functional teams to enhance pharmacy utilization management a...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$114K - $171K *

Join a team that's driving growth in clinical trials by identifying and securing partnerships. Collaborate with cross-functional leaders to enhance visibility and expand opportunities, ensuring seamle...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$232K - $348K *

Elevate customer understanding by leading analytics teams to deliver actionable insights that drive strategic decisions and enhance customer experiences across diverse markets and stakeholders...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.