Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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$90K - $110K *

Join a team that's dedicated to identifying and recruiting top-tier leadership talent across various sectors. Engage in full-cycle recruiting or selected stages, leveraging your expertise to connect w...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$200K - $215K *

Advance the cloud platform capabilities, ensuring secure, reliable, and scalable product delivery while enhancing developer experience and shaping reliability practices in a mission-driven healthcare...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$100K - $120K *

Empower our provider team's mission by designing innovative tools for therapists. You'll create streamlined solutions that enhance patient care, drive efficiency, and leverage technology while collabo...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $230K *

Drive impactful oncology solutions by building relationships with key stakeholders, promoting innovative products, and exceeding performance goals in a dynamic biopharma environment. Collaborate effec...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Optimize integration processes by bridging technical gaps between systems. Collaborate with campus IT to ensure seamless data flows, troubleshoot issues, and enhance integration reliability for succes...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$199K - $269K *

Shape patient affordability strategies by leading a dynamic team focused on co-pay programs and innovative solutions. Collaborate cross-functionally to enhance operations, optimize performance, and dr...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$160K - $192K *

Drive commercial performance by engaging healthcare providers and executing territory plans. Collaborate with cross-functional teams to support product launches and ensure patient access to innovative...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Lead a dynamic team of travel therapy recruiters while driving personal production. Champion recruitment strategies, enhance team performance, and ensure alignment with client demands to achieve booki...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Staffing

$160K - $192K *

Lead the charge in driving commercial performance by engaging healthcare providers, building relationships, and executing territory business plans to ensure patient access to innovative therapies and...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Transform your career by leading initiatives that enhance patient care and safety. Collaborate with teams to implement best practices, manage budgets, and foster a culture of trust and accountability...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$90K - $110K *

Empower your career by driving project delivery and managing Agile teams. Utilize AI tools to enhance decision-making, anticipate risks, and ensure timely outcomes. Collaborate with stakeholders to ma...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$140K - $190K *

Shape the future of healthcare revenue cycle performance by leading transformative initiatives, optimizing client success, and fostering innovation across multiple healthcare partnerships. Drive measu...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Champion the future of mental healthcare by architecting innovative solutions for Provider Onboarding. Lead a dynamic team to enhance tools and workflows, ensuring seamless integration for users while...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $140K *

Elevate healthcare consulting by leading complex actuarial projects, developing financial models, and advising clients on policy impacts. Collaborate with teams to analyze data, mentor analysts, and e...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$120K - $145K *

Empower regulatory excellence by guiding cross-functional teams in compliance and strategy. Leverage deep FDA knowledge to influence promotional materials and ensure adherence to evolving regulations...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$195K - $237K *

Optimize the renter experience across digital platforms by leading design initiatives, balancing innovation with maintenance, and setting high standards for visual and interaction design. Collaborate...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$101K - $146K *

Unlock potential by leading payer contract negotiations to enhance relationships, optimize revenue, and ensure compliance with regulations, all while aligning with strategic priorities of the health s...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$162K - $195K *

Deliver impactful sales strategies and cultivate strategic partnerships to launch a groundbreaking cardiac treatment in your territory, effectively addressing unmet patient needs while collaborating w...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$145K *

Drive innovation and transform lives by leading regulatory strategies and submissions for clinical trials globally. Act as a key liaison for project teams to ensure compliance, operational excellence...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $100K *

Unlock insights by analyzing customer and operational data to enhance business outcomes. Collaborate with cross-functional teams to develop dashboards and reports that drive strategic decisions and im...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Lead the charge in delivering exceptional pharmaceutical care to adult patients in acute settings. Collaborate with interdisciplinary teams to ensure safe medication practices and provide education wh...

3 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$124K - $170K *

Champion regulatory strategies to accelerate product approvals and compliance. Lead a dynamic team in supporting innovative medical devices, ensuring alignment with global regulations while fostering...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$177K - $221K *

Champion regulatory excellence by leading cross-functional teams, ensuring compliance, and driving successful oncology drug development through strategic planning and expert guidance...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Accelerate commercial growth by defining strategies for product families, collaborating across teams to translate market insights into actionable plans that drive revenue, profitability, and customer...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Healthcare

$90K - $115K *

Elevate your career by leading innovative social media programs that connect healthcare clients with their audiences. Drive strategic content development and manage cross-functional teams to ensure im...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.