Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down

Sort By: Relevance

$95K - $115K *

Unlock potential by leading analytics initiatives, transforming data into actionable insights, and mentoring junior analysts. Collaborate with stakeholders to enhance reporting solutions and drive ope...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $125K *

Transform healthcare analytics by leading the development of APR-DRG audit criteria. Collaborate with cross-functional teams to enhance payment integrity through data-driven insights and innovative so...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Business Services

$125K - $150K *

Shape the future of healthcare by leading non-clinical support services. Drive operational excellence and spearhead major construction initiatives, ensuring compliance and exceptional patient care in...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$160K - $192K *

Drive commercial performance by engaging healthcare providers and executing territory plans. Collaborate with cross-functional teams to support product launches and ensure patient access to innovative...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$103K - $128K *

Join us to lead product strategy and development, driving innovation and performance in healthcare solutions. Collaborate cross-functionally to align business needs with customer expectations and ensu...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Elevate data privacy standards by leading a comprehensive privacy program. Collaborate across teams to integrate privacy-by-design principles, enhance data governance, and ensure compliance while enab...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Lead cross-functional projects in health plan relations, enhancing revenue cycle performance and outcomes. Utilize strong communication and project management skills to coordinate initiatives, track p...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Healthcare

$92K - $138K *

Lead the strategic management of accounts receivable functions, optimizing cash flow and ensuring compliance. Collaborate with teams to enhance efficiency, resolve escalations, and drive performance a...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Empower individuals by providing comprehensive psychological assessments and treatment plans. Collaborate with a multidisciplinary team to enhance patient care and contribute to operational excellence...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$130K - $155K *

Elevate your career by joining a dynamic Medical Affairs team, where you'll lead Medical Information initiatives, ensure compliance, and drive strategic insights to support our innovative pipeline in...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$180K - $215K *

Drive regional sales success by leading a high-performing team, executing launch strategies, and fostering customer relationships to achieve business objectives in a dynamic environment...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$242K - $303K *

Join as the primary privacy leader to manage and enhance an enterprise-wide privacy program while navigating complex regulations. Collaborate across departments to drive compliance, innovation, and ef...

United StatesRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$183K - $220K *

Lead strategic initiatives for Integrated Delivery Networks and health systems, optimizing patient access and formulary adoption. Build executive relationships and drive clinical integration to enhanc...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$130K - $143K *

Optimize your career by developing and executing clinical marketing strategies that enhance customer engagement and drive adoption of innovative patient monitoring solutions. Collaborate with cross-fu...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Healthcare

$140K - $170K *

Shape the future of healthcare technology by leveraging your expertise to drive sales success. Collaborate with cross-functional teams to deliver tailored solutions, engage customers, and enhance prod...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$118K - $144K *

Unlock your potential by driving marketing performance through data analysis, reporting, and strategic insights. Collaborate with cross-functional teams to enhance decision-making and optimize growth...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$90K - $178K *

Drive post-award site identification efforts by developing strategies, managing feasibility questionnaires, training resources, and coordinating outreach to ensure optimal site activation and client c...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Shape the future of procurement by leading strategic sourcing initiatives, enhancing vendor relationships, and driving financial transparency. Collaborate across teams to streamline processes and leve...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Shape client success by leading complex consulting projects, integrating diverse workstreams into actionable insights, and driving high-quality deliverables while fostering team growth and managing st...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$227K - $385K *

Elevate member care by overseeing utilization management and evaluating treatment appropriateness. Collaborate with multidisciplinary teams, ensuring compliance with clinical standards and regulations...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Advance your career by ensuring safe medication practices and enhancing patient care. Collaborate with healthcare professionals to review prescriptions, resolve drug-related issues, and provide except...

2 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$150K - $180K *

Shape the future of AI by leading technical direction and architecture for innovative agent systems. Collaborate with cross-functional teams to ensure quality, security, and efficiency while mentoring...

United StatesRemote

4 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$75K - $100K *

Reimagine talent acquisition by leading full-cycle recruiting efforts, collaborating with leadership to forecast hiring needs, and enhancing employer branding to attract top talent while ensuring comp...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$94K - $125K *

Empower your career with an impactful role driving sales of complex supply chain solutions in healthcare. Engage C-suite executives, manage strategic accounts, and address industry challenges to deliv...

United StatesRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$200K - $250K *

Transform provider engagement by leading peer-to-peer conversations and ensuring clinical governance. Leverage your medical expertise to enhance patient safety and optimize drug strategies while repre...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.