Find professional opportunities in West Virginia with salaries of $100,000 or more on Ladders. Browse vetted openings across the Mountain State, from established employers in Charleston and Huntington to opportunities in Morgantown, Wheeling, and beyond. Whether you’re pursuing your next leadership role or bringing specialized expertise to a growing organization, discover jobs that match your experience and career goals.
West Virginia’s professional job market spans healthcare, energy, engineering, technology, finance, education, and management. Employers seek experienced clinicians and healthcare leaders, engineers and energy specialists, technology professionals, executives, and other seasoned talent. Available roles and salary ranges vary by employer, location, and qualifications.
Explore openings in urban centers such as Charleston, Huntington, and Morgantown, as well as roles throughout the state. Some positions may offer remote or hybrid work, while others require an on-site presence. Review each listing for its location, work arrangement, compensation, and requirements.
Use Ladders to search vetted jobs with salaries of at least $100,000. Filter opportunities by title, industry, and location, then compare responsibilities and qualifications to identify roles aligned with your background. Keep your resume current and tailor your application to highlight the expertise and measurable results employers value.
Average Salary: $124,705
$120K - $180K *
Explore the evolving landscape of health habits in America. Play a key role in analyzing trends, reporting on policies, and engaging with influential figures to shape the national conversation on well...
2 weeks ago
Outside Sales Engineer (Dallas/Fort Worth)
$80K - $95K *
Champion sales growth by leveraging your engineering expertise and relationship-building skills. Drive customer engagement and develop tailored solutions in a dynamic market, while managing the sales...
2 weeks ago
Sr. Software Engineer - Platform
$189K - $231K *
Build next-gen AI infrastructure as a Senior Engineer, owning subsystems from design to production. Shape projects for enterprise clients by leading and mentoring engineers while tackling unique infra...
Reposted 2 weeks ago
Principal, Cloud Solutions Architect
$208K - $235K *
Innovate and lead the development of scalable cloud solutions, ensuring high engineering standards and strategic architecture. Collaborate with cross-functional teams to translate business needs into...
2 weeks ago
Incident Response Coordinator, Senior
$110K - $130K *
Drive incident response excellence by coordinating complex IT incidents, fostering cross-team collaboration, and producing clear, executive-ready communications to mitigate mission impact and enhance...
Reposted 2 weeks ago
$125K - $150K *
Provide advanced Hogan ILP development support through coding, design, and testing for our client's system. Work collaboratively on technical solutions, focusing on enhancing application performance a...
Reposted 2 weeks ago
Level 3 Managed Services Engineer -- Microsoft
$95K - $115K *
Join a team that's dedicated to optimizing Microsoft-based systems, providing advanced technical support, and enhancing IT infrastructure. Collaborate with experts to resolve complex issues and drive...
2 weeks ago
$120K - $145K *
Join a dynamic team to lead technical pre-sales engagements, translating advanced AI solutions into impactful business outcomes for enterprise clients. Collaborate closely with sales and engineering t...
2 weeks ago
Enterprise Account Executive-Midwest
$119K - $155K *
Shape the future of enterprise sales by driving growth and cultivating long-term relationships. Manage complex sales cycles and leverage AI tools to optimize efficiency and insights, ensuring customer...
Reposted 2 weeks ago
Founding Mobile Engineer (React Native)
$125K - $150K *
Champion the mobile experience by architecting and building a React Native platform. Influence product direction and engineering standards while delivering AI-powered features that enhance customer in...
2 weeks ago
$120K - $145K *
Join a dynamic Reliability team as a Senior Database Engineer, enhancing database performance and reliability. Collaborate across engineering to optimize distributed databases, ensuring high availabil...
2 weeks ago
AD/Director, Regulatory Affairs CMC
$190K - $285K *
Advance regulatory strategies for global CMC submissions, managing cross-functional collaboration and internal processes to meet compliance with health authority standards, while leveraging strong com...
Reposted 2 weeks ago
Director of Statistical Programming
$241K - $269K *
Drive statistical programming excellence across multiple clinical studies while collaborating with cross-functional teams. Lead validation of CRO deliverables and implement innovative tools to enhance...
Reposted 2 weeks ago
Director/Sr. Director Clinical Pharmacology
$262K - $284K *
Optimize pediatric drug development strategies as a clinical pharmacology leader, overseeing pharmacometric analyses and regulatory submissions, while translating complex data into actionable decision...
Reposted 2 weeks ago
Biostatistics Director, Medical Affairs
$222K - $255K *
Lead the biostatistical strategies that support impactful medical communication efforts. Collaborate cross-functionally to provide scientific expertise, develop publication strategies, and ensure meth...
Reposted 2 weeks ago
Senior Software Engineer II - Agentic Intelligence
$183K - $206K *
Partner with us to innovate agent engineering, crafting unique observability solutions using high-cardinality data. Lead projects from prototype to production while enhancing Canvas capabilities for i...
Reposted 2 weeks ago
$120K - $145K *
Drive your career with a pivotal role in shaping product strategy and delivery, enhancing member experiences in healthcare. Collaborate across teams to define problems, prioritize outcomes, and levera...
2 weeks ago
Clinical Laboratory Supervisor
$91K - $100K *
Join a team that's dedicated to excellence in clinical lab operations, overseeing staff performance and ensuring compliance with quality standards. Lead daily activities, foster team development, and...
2 weeks ago
VP, Global Head of Commercial Transactions
$227K - $315K *
Lead global commercial legal efforts, overseeing seasoned attorneys in negotiating complex technology and commercial agreements. Drive strategy and collaboration for scalable growth while ensuring leg...
Reposted 2 weeks ago
Manager Transmission Planning - Transmission Planning & Protection
$110K - $130K *
Join a team that's dedicated to ensuring the safe and reliable operation of transmission systems. Lead a diverse group of engineers and supervisors in planning and executing critical projects while fo...
2 weeks ago
$76K - $95K *
Explore opportunities as a Customer Success Manager, fostering customer relationships, analyzing data to mitigate risks, and advocating for client needs to enhance service adoption. Bring your experti...
Reposted 2 weeks ago
Senior Program Engineer, IT Services & Cloud Operations
$120K - $150K *
Drive complex federal platform initiatives, enhancing security, compliance, and infrastructure through innovative engineering solutions and cross-functional leadership...
Reposted 2 weeks ago
Senior Technical Product Manager, Privileged Access Management (PAM)
$125K - $150K *
Drive the evolution of a next-gen Privileged Access Management platform, collaborating across teams to create user-centric and secure solutions while ensuring technical excellence and scalability in a...
Reposted 2 weeks ago
Software Development Test Engineer (SDET), Android
$110K - $130K *
Engage with us to enhance Android automation testing. Collaborate in designing robust test frameworks, ensuring quality through innovative CI/CD integration, and optimizing app performance across devi...
Reposted 2 weeks ago
Senior Software Engineer, Browser Extension
$120K - $145K *
Develop and enhance browser extension features that secure user experiences. Collaborate with product teams and implement best coding practices to optimize performance and usability, all while maintai...
Reposted 2 weeks ago
What types of high-paying jobs are available in West Virginia?
Openings can include positions in healthcare, energy, engineering, technology, finance, education, and executive management. Availability changes over time, so browse current listings for the latest opportunities.
Are West Virginia jobs on Ladders vetted?
Ladders features vetted professional jobs paying $100,000 or more. Check each listing for details about the employer, compensation, responsibilities, and qualifications.
Which West Virginia cities have professional job opportunities?
Opportunities may be found in Charleston, Huntington, Morgantown, Wheeling, and other communities across the state. Search by location to see current openings.
Can I find remote jobs based in West Virginia?
Some listings may offer remote or hybrid work, while others are location-based. Review the work arrangement specified in each job posting.
How can I find a $100,000-plus job in West Virginia?
Search West Virginia listings on Ladders, filter by location or role, and review positions that meet your salary and experience goals. Tailor your resume to the qualifications and results emphasized in each posting.