Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Corporate Technology Support Engineer
$75K - $106K *
Manage high-quality technical support for corporate users, ensuring seamless operation of Windows and macOS devices, Microsoft 365, and endpoint technologies. Drive improvements in support processes a...
4 weeks ago
GIS Software Quality Assurance Engineer
$95K - $120K *
Champion quality assurance in GIS software by developing test plans, validating data, and ensuring reliability for Army geospatial applications. Collaborate with experts to enhance automated testing p...
2 weeks ago
Senior Technical Product Manager, IT Service Management
$143K - $169K *
Lead the transition to a modern, AI-native ITSM platform, enhancing service management across teams. Drive employee-centric design, streamline workflows, and ensure seamless integration while maintain...
Reposted 2 weeks ago
Sr. Lead OBT Implementation Manager
$185K - $210K *
Lead the charge in transforming TMC implementations by defining processes, configuring platforms, and training teams to ensure seamless transitions and rapid go-lives across multiple projects simultan...
2 weeks ago
Senior Manager Tax Technology and Process Transformation
$126K - $150K *
Pioneer the transformation of tax technology and processes, driving strategic initiatives to enhance operational efficiency, compliance, and user experience through automation and data-driven solution...
4 weeks ago
$160K - $190K *
Transform user engagement by owning product roadmaps, collaborating cross-functionally, and leveraging data to drive impactful solutions. Engage with customers to identify opportunities and validate h...
1 week ago
$120K - $145K *
Elevate security standards by leading bug bounty programs, conducting audits, and enhancing software supply chain security. Collaborate across teams to build innovative tools that protect users and en...
2 weeks ago
$100K - $122K *
Join a team that's redefining DevOps by building and maintaining CI/CD pipelines, automating workflows, and enhancing service delivery in AWS. Collaborate with cross-functional teams to ensure reliabl...
3 weeks ago
Senior Enterprise Implementation Consultant
$100K - $165K *
Join our Strategic Customer Success team to guide enterprise clients in deploying IoT solutions, enhancing business value. You'll manage relationships, ensuring a successful launch and continuous enga...
Reposted 2 days ago
$186K - $203K *
Design impactful monetization experiences that enhance user engagement and drive revenue. Collaborate with cross-functional teams to create seamless, user-centered journeys while leveraging AI tools t...
3 weeks ago
$130K - $140K *
Shape the future of AI-driven financial advice by designing intuitive, impactful products. Collaborate closely with PMs and engineers to create solutions that enhance user experience and drive results...
1 week ago
Senior / Lead Site Reliability Engineer
$112K - $154K *
Advance your career as a Senior Site Reliability Engineer, focusing on automation, reliability, and performance. Collaborate with teams to enhance application performance and operational efficiency wh...
Today
$86K - $137K *
Optimize project outcomes as you manage small to medium-sized initiatives. Collaborate across teams, navigate risks, and ensure timely delivery of quality solutions while enhancing communication and s...
Reposted 1 week ago
Senior Product Marketing Manager, Growth
$180K - $220K *
Drive impactful product launches and enhance user activation flows to ensure customer adoption and satisfaction. Collaborate cross-functionally to create effective onboarding experiences and measure s...
1 week ago
$93K - $146K *
Champion sustainable design by leading complex mechanical systems for high-performance buildings, ensuring compliance with advanced standards and certifications while driving innovative engineering so...
5 days ago
Senior Product Marketing Manager, AI
$126K - $134K *
Unlock potential by leading product marketing for AI solutions. Shape messaging, drive competitive intelligence, and create impactful content to connect technology with customer value. Collaborate cro...
1 week ago
Data Engineer - AWS / Snowflake
$110K - $130K *
Join a dynamic team to design and implement scalable data pipelines using AWS and Snowflake. Collaborate with clients to transform data workflows and deliver high-quality solutions that drive business...
Today
$127K - $237K *
Join a team that's driving digital transformation by enhancing products and services, managing strategic initiatives, and developing talent to achieve organizational goals while ensuring optimal perfo...
Reposted 3 days ago
$59K - $110K *
Engage with patients and caregivers to enhance their treatment journey through education and support. Collaborate with teams to ensure quality service and compliance while driving innovative solutions...
Today
$60K - $120K *
Unlock potential by deploying and supporting advanced robotic systems in diverse environments. Collaborate with teams, troubleshoot issues, and enhance client experiences through effective communicati...
4 weeks ago
$90K - $110K *
Lead the charge in resolving complex technical issues, enhancing support processes, and collaborating with engineering teams to improve product functionality and customer satisfaction in a dynamic B2B...
Reposted today
Sr. Digital Experience Manager
$110K - $130K *
Champion the digital experience by optimizing user flows, managing web content, and enhancing conversion strategies to drive engagement and pipeline growth for a leading B2B SaaS platform...
3 weeks ago
Vice President, Enterprise PMO
$247K - $345K *
Unlock potential by leading enterprise-wide strategic initiatives, optimizing program execution, and enhancing technology portfolio management. Drive cross-functional collaboration and operational eff...
4 weeks ago
$80K - $155K *
Join a team that's redefining energy solutions by designing innovative fluid and power systems. As a Process Engineer, you'll drive the development and optimization of cutting-edge technologies in a f...
2 weeks ago
Senior Expert Robotics Engineering
$158K - $207K *
Transform robotics capabilities across manufacturing by leading strategy, validation, and deployment of advanced automation solutions, enhancing safety, productivity, and operational performance in fa...
3 weeks ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.