Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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$126K - $200K *

Lead technical solutions architecture for HPE storage platforms, guiding partners and sales teams in developing resilient infrastructure solutions. Drive engagement, enablement, and strategic initiati...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

$126K - $200K *

Drive your career forward by providing technical leadership and innovative solutions in enterprise networking. Collaborate with partners to enhance sales engagement and architect cutting-edge solution...

RemoteRemote

4 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$100K - $120K *

Lead the charge in transforming legacy messaging solutions to modern Google technologies. Utilize your expertise in Google Workspace migrations and project management to drive successful deployments a...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Drive global functional leadership for Infor M3 Finance, translating business needs into scalable solutions while ensuring alignment with global templates and minimizing customization...

2 days ago

  •   Less than 5 years exp.  •   Information Technology

$147K - $198K *

Lead a dynamic software development team, driving modernization and secure engineering practices across legacy and cloud-native systems while fostering collaboration and high-quality delivery...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $188K *

Elevate your career by designing and building innovative data solutions that empower genomic research and analysis. Collaborate with scientists in a fast-paced R&D environment to support impactful dis...

United StatesRemote

Reposted 1 month ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Join a team that's dedicated to troubleshooting and enhancing trading connectivity. You'll support core trading operations, manage exchange onboarding, and ensure seamless order routing across multipl...

Yesterday

  •   Less than 5 years exp.  •   Finance & Insurance

$96K - $160K *

Transform the future of data centers by leading commissioning efforts for critical electrical and mechanical systems. Collaborate with diverse teams to ensure quality, compliance, and efficiency in hi...

Yesterday

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$94K - $179K *

Lead quality initiatives by optimizing test strategies and automation processes. Collaborate with cross-functional teams to ensure high-quality software delivery while mentoring engineers and driving...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$135K - $160K *

Transform observability in AI with strategic vision, driving technical progress across systems and agent telemetry, while enhancing developer experiences and guiding product direction at the intersect...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$135K - $160K *

Join a team that's redefining data architecture by leading innovative modeling and integration initiatives. Collaborate with AI Engineers to create scalable datasets and optimize performance in a mult...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$207K - $218K *

Unlock potential by designing and scaling backend systems for high-value financing operations, ensuring safety and reliability while driving revenue and trading activity in a dynamic financial environ...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$130K - $160K *

Lead engineering efforts by writing production code and mentoring a team. Drive modernization initiatives through Java microservices while managing performance and growth of engineers. Collaborate wit...

United StatesRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Enterprise Technology

$160K - $185K *

Shape the future of data engineering by leading the architecture and evolution of a robust enterprise data platform, ensuring reliability and integration across analytics, reporting, and AI capabiliti...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Retail & Consumer Goods

$68K - $131K *

Join a team that's dedicated to engineering excellence, coordinating with cross-functional teams to meet technical requirements, manage budgets, and ensure timely hardware delivery while utilizing Agi...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$100K - $120K *

Lead the charge in optimizing project management processes for a VHA client team. Utilize your expertise to enhance strategic planning, decision-making, and execution while collaborating with senior s...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$193K - $309K *

Lead the charge in transforming care agent tools, enhancing system reliability and performance. Collaborate with cross-functional teams to design and implement solutions that streamline support proces...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$100K - $120K *

Analyze customer needs and advance technical solutions in cybersecurity, collaborating with sales and product teams to deliver impactful presentations and proposals while ensuring seamless product int...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$105K - $177K *

Elevate your career by mastering Oracle software engineering in a dynamic, remote environment. Collaborate with a skilled team to enhance database performance and support critical applications while d...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Information Technology

$117K - $157K *

Join a team that's transforming enterprise AI solutions through innovative design and deployment. Leverage your expertise to build secure, scalable AI platforms that enhance business processes and dri...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $145K *

Join a team that's shaping the future of software development by leading projects, mentoring engineers, and architecting innovative solutions that enhance performance and meet business goals in a coll...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Advance software development by leading projects, mentoring engineers, and architecting solutions. Collaborate across teams to enhance performance and functionality while staying updated on technology...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$200K - $250K *

Elevate the search experience by designing and evolving a robust backend system that powers millions of searches. Collaborate across teams to enhance scalability, reliability, and maintainability whil...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Champion project delivery by overseeing HV cable testing projects across North America. Ensure alignment with client expectations while managing resources, schedules, and budgets for successful comple...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Energy & Utilities

$286K - $326K *

Champion engineering excellence by leading high-performing teams to innovate scalable, customer-centric solutions. Drive technical strategy and architecture while fostering a culture of continuous lea...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.