Senior Systems Engineer Jobs at Ladders

Welcome to our comprehensive job board for Senior Systems Engineers. Here at Ladders, we’re dedicated to offering you the highest paying positions in prestigious companies. Find Senior Systems Engineer roles that match your skills, experience, and ambitions.

What is a Senior Systems Engineer?

A Senior Systems Engineer is responsible for the design, implementation, and maintenance of complex computer systems within a company. They play a critical role in ensuring the IT infrastructure's performance, reliability, and security.

Find Your Dream Job at Ladders

With Ladders, your dream of landing a high-paying Senior Systems Engineer role is in reach. Join us today to discover the myriad opportunities we have to offer.

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$105K - $121K *

Drive the design, development, and maintenance of enterprise applications, emphasizing Microsoft Dynamics 365 and Power Pages. Collaborate in Agile teams to enhance scalability and support critical bu...

US-AnywhereRemote

Yesterday

  •   Less than 5 years exp.  •   Enterprise Technology

$247K - $275K *

Lead the charge in advancing internal network and Active Directory attack strategies for enterprise protection, turning cutting-edge techniques into reliable, autonomous solutions within a collaborati...

US-AnywhereRemote

4 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$140K - $233K *

Empower teams to integrate security across the software development lifecycle, focusing on AI-enabled products and DevSecOps practices. Collaborate with cross-functional teams to enhance security and...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $95K *

Transform customer experiences by providing exceptional technical support and solutions for centrifugal and vacuum pumps, ensuring seamless operations and sustainable equipment performance across dive...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Energy & Utilities

$65K - $98K *

Join a dynamic team to serve as a Senior Financial Analyst, providing insights through financial analysis and supporting budgeting/forecasting efforts while ensuring financial accuracy and collaborati...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$131K - $237K *

Optimize secure, scalable cloud infrastructures for critical U.S. Government applications. Collaborate across technical teams to enhance deployment, integrating best practices and reusable architectur...

US-AnywhereRemote

1 week ago

  •   11 - 15 years exp.  •   Information Technology

$112K - $123K *

Engage with partners to drive the adoption of innovative data and AI solutions, overseeing technical strategy, architecture, and sales execution while ensuring successful partner collaboration in the...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Technical Services

$152K - $223K *

Join a forward-thinking team shaping the future of enterprise integration through innovative API strategies, driving automation and fostering collaboration across technologies to enhance business outc...

US-AnywhereRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$120K - $145K *

Transform the future of oncology by managing global clinical trials from inception to completion. Collaborate cross-functionally to ensure quality and timely execution while addressing significant unm...

US-AnywhereRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Drive success at our member-facing platforms by leading technical teams, enhancing collaboration, and fostering a culture of continuous improvement in a dynamic, remote environment...

US-AnywhereRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Invent robust agentic systems for biomedical data acquisition, cleaning, and quality control. Collaborate with ML scientists to enhance data processing for large-scale LLM applications. Build scalable...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$140K - $165K *

Transform quality assurance practices by developing innovative testing strategies. Collaborate with engineering teams and stakeholders to ensure robust solutions meet performance and security standard...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$200K - $230K *

Lead backend development ensuring scalable, reliable systems while mentoring others. Shape product features with your expert coding skills and architect complex applications utilizing AI and ML techni...

US-AnywhereRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $130K *

Join a team that's committed to building, maintaining, and enhancing high-performance network infrastructure, ensuring optimal availability and security for our government client through innovative so...

US-AnywhereRemote

6 days ago

  •   8 - 10 years exp.  •   Information Technology

$120K - $150K *

Shape the future of geometric modeling by developing innovative algorithmic solutions. Collaborate with cross-functional teams, mentor junior developers, and focus on delivering quality code while enh...

US-AnywhereRemote

6 days ago

  •   5 - 7 years exp.  •   Technical Services

$141K - $212K *

Pioneer innovative managed service solutions by leading technical engagements with MSP partners. Shape enterprise data strategies and drive competitive wins through architectural design, commercial fl...

US-AnywhereRemote

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$180K - $270K *

Champion engineering excellence by developing methodologies and tools for scalable, high-quality product development. Partner with teams to drive digital transformation and improve engineering product...

US-AnywhereRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$110K - $177K *

Champion enterprise AI infrastructure by leading Kubernetes migrations, platform modernization, and hands-on deployment; work embedded with clients to drive engineering excellence and optimize product...

US-AnywhereRemote

2 weeks ago

  •   11 - 15 years exp.  •   Enterprise Technology

$89K - $100K *

Deliver innovative solutions by supporting the implementation and configuration of digital banking products. Collaborate with clients and teams to troubleshoot issues, ensure quality, and achieve succ...

US-AnywhereRemote

6 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$156K - $255K *

Deliver expert pre-sales support and connect client needs to impactful solutions, driving comprehensive product demonstrations and ensuring successful onboarding for enhanced customer outcomes and lon...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$150K - $220K *

Contribute to corporate security by designing, implementing, and maintaining robust security measures while collaborating with IT, engineering, and business teams to address and mitigate risks across...

US-AnywhereRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Empower your career as a Senior Pharma Business Analyst, collaborating with Life Sciences clients to drive data and analytics initiatives while translating business needs into actionable solutions, en...

US-AnywhereRemote

5 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$240K - $275K *

Empower transformation initiatives in AI, driving product innovation and productivity. Lead cross-functional teams to adopt AI capabilities, shaping software delivery and enhancing customer experience...

US-AnywhereRemote

1 week ago

  •   11 - 15 years exp.  •   Enterprise Technology

$156K - $205K *

Empower growth by leveraging your data expertise to enhance GTM strategies. Collaborate globally, ensuring reliable data pipelines and insightful dashboards that drive key performance metrics across t...

US-AnywhereRemote

6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$119K - $202K *

Advance your career by leading the design of distribution substations, ensuring high-quality deliverables while collaborating with multidisciplinary teams and mentoring junior engineers for continuous...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Energy & Utilities

Frequently Asked Questions (FAQ)

  • What do Senior Systems Engineers do?question toggle

    Senior Systems Engineers are responsible for designing, implementing, and maintaining complex systems within a company. They ensure the IT infrastructure performs optimally and is secure.

  • How much do Senior Systems Engineers make?question toggle

    The salary of a Senior Systems Engineer can vary based on the geographical location, industry, and company size. However, all Senior Systems Engineer jobs listed on Ladders offer salaries over $100,000.

  • What qualifications do I need to be a Senior Systems Engineer?question toggle

    A Bachelor’s degree in computer science, engineering, or a related field is typically required. Many employers also value professional certifications and significant experience in the field.