Discover Senior Principal Systems Engineer Jobs

Welcome to our category for Senior Principal Systems Engineer roles. You'll find a range of opportunities spanning from systems development to technical leadership.

Senior Principal Systems Engineer Roles

As a Senior Principal Systems Engineer, you'll oversee system architecture, guide technical teams, and address the most complex engineering challenges.

Where Your Skills are Valued

Ladders values your high-level analytical, design and leadership skills. Join us, expand your career opportunities and land the job you're aiming for.

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$125K - $147K *

Join our team to innovate Salesforce support solutions, drive technical excellence, and lead a talented development pod focused on enhancing user experience across our Salesforce platforms...

US-AnywhereRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$69K - $125K *

Champion the execution of complex distribution planning studies, focusing on capacity assessment, thermal loading analysis, and impact evaluations for utility clients while collaborating with multidis...

US-AnywhereRemote

3 days ago

  •   Less than 5 years exp.  •   Energy & Utilities

$69K - $125K *

Shape the future of energy distribution! Join us in executing advanced planning studies and analyses to optimize utility operations, ensuring a reliable and efficient energy grid. Collaborate directly...

US-AnywhereRemote

4 days ago

  •   Less than 5 years exp.  •   Energy & Utilities

$163K - $194K *

Drive the development of AI-native infrastructure solutions to support 200+ backend services. Collaborate on scalable platforms while managing complex reliability challenges. Leverage AI to enhance op...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$72K - $130K *

Engineer the future of cloud-based call center solutions by enhancing application reliability and performance. Collaborate cross-functionally to support modernization initiatives, ensuring systems are...

US-AnywhereRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $160K *

Transform enterprise collaboration with your architectural leadership. Drive architecture decisions for Microsoft 365, Exchange, Entra ID, and Teams in a fast-paced, highly regulated environment while...

US-AnywhereRemote

Reposted 5 days ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$130K - $160K *

Help us elevate federal collaboration and messaging platforms by leading architectural decisions, optimizing enterprise solutions, and ensuring compliance in a heavily regulated environment with your...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$150K - $200K *

Transform client relationships by leading portfolio management, ensuring delivery excellence, and driving business growth while engaging with senior stakeholders to innovate solutions and capture emer...

US-AnywhereRemote

Reposted 6 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$190K - $220K *

Join us to reshape lifecycle marketing strategies with data-driven automation, enhancing guest experiences across email, SMS, and push notifications. Influence high-impact initiatives while collaborat...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Consumer Technology

$160K - $260K *

Innovate tailored infrastructure solutions that meet client needs, collaborating across data centers, cloud, and security. Build relationships with partners and provide technical training while managi...

US-AnywhereRemote

3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$121K - $173K *

Lead the charge in optimizing WMS across multiple warehouses while supporting key transitions and ensuring continuous operational improvement through collaboration and strategic analysis...

US-AnywhereRemote

5 days ago

  •   8 - 10 years exp.  •   Technical Services

$120K - $150K *

Transform cloud strategies by providing technical leadership in DevOps and platform engineering. Define best practices for Azure-based infrastructure, automation, and data integrations while mentoring...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$160K - $260K *

Drive innovative infrastructure solutions by collaborating with clients and teams to assess data center needs. Cultivate relationships with OEMs, lead training efforts, and identify growth opportuniti...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$102K - $171K *

Elevate healthcare innovation by owning the downstream strategy of AI-enabled digital solutions, driving engagement and adoption through effective storytelling and cross-functional collaboration...

US-AnywhereRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$107K - $143K *

Lead the charge in managing critical data center construction projects. Oversee multi-disciplinary teams to deliver on-time, within budget solutions while ensuring top-notch quality and compliance wit...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$138K - $162K *

Lead the charge in designing and maintaining cutting-edge data infrastructure, optimizing data solutions for collaboration across teams. Drive high-quality data integration and analytics to support or...

US-AnywhereRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Information Technology

$145K - $155K *

Lead and optimize complex manufacturing programs across multiple sites, ensuring compliance and cost-effectiveness while managing cross-functional teams to meet environmental, safety, and operational...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$189K - $246K *

Lead the charge in technical oversight of small molecule API development and manufacturing to drive successful product milestones and support lifecycle management. Collaborate cross-functionally to en...

US-AnywhereRemote

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$160K - $190K *

Unlock your potential by leading the design and execution of multi-cloud architectures. Collaborate with cross-functional teams to drive innovations in AI and cloud infrastructure, ensuring scalabilit...

US-AnywhereRemote

6 days ago

  •   8 - 10 years exp.  •   Information Technology

$105K - $125K *

Pioneer the development of robust software solutions in eDiary and clinical data platforms, leveraging modern technologies to enhance patient engagement and ensure regulatory compliance while collabor...

US-AnywhereRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$79K - $127K *

Unlock potential by delivering exceptional service in complex power delivery projects. Engage with customers to enhance system performance, lead field assignments, and cultivate expertise within a col...

US-AnywhereRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$90K - $130K *

Empower growth initiatives in the Air Force market by identifying and qualifying new business opportunities, fostering collaborations, and maintaining key relationships for success across diverse busi...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$160K - $193K *

Join a dynamic team to lead the development of innovative middleware solutions for autonomous trucking, focusing on GPU optimization and deep learning model integration, while nurturing a high-perform...

US-AnywhereRemote

3 days ago

  •   Less than 5 years exp.  •   Transportation

$140K - $175K *

Shape the future of energy engineering by leading innovative modeling practices, mentoring teams, and integrating advanced technology across projects, enhancing ECM development and analysis to drive e...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Energy & Utilities

$120K - $150K *

Collaborate with cross-functional teams to implement and deploy cloud solutions, applying XP engineering practices and mentoring others to foster growth. Engage closely with clients to adapt solutions...

US-AnywhereRemote

3 days ago

  •   Less than 5 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What does a Senior Principal Systems Engineer do?question toggle

    A Senior Principal Systems Engineer handles system architecture, leads technical teams, and solves advanced engineering problems. They're often responsible for guiding overall system design and integration.

  • What skills do I need to have for these roles?question toggle

    Skills commonly required include system design, team leadership, analytical thinking and knowledge in systems integration.

  • What industries hire Senior Principal Systems Engineers?question toggle

    Industries like Technology, Aerospace, Defense, Telecommunications, and more require the expertise of Senior Principal Systems Engineers.