Explore senior data scientist opportunities with organizations seeking experienced professionals to turn complex data into meaningful business results. Ladders features vetted jobs paying $100,000 or more, helping you focus your search on roles that match your skills, leadership experience, and compensation goals.
Senior data scientists design analytical approaches, build and evaluate statistical and machine learning models, and translate findings into practical recommendations. They work with product, engineering, business, and executive teams to identify opportunities, guide decisions, and deliver data-driven solutions.
Employers often look for advanced experience in Python or R, SQL, statistical analysis, machine learning, experimentation, and data visualization. Senior candidates may also bring expertise in cloud platforms, large-scale data systems, model deployment, and responsible AI. Clear communication, sound judgment, and the ability to mentor teammates are also valuable.
Senior data scientists can find opportunities across technology, finance, healthcare, retail, consulting, and other data-intensive industries. Depending on the organization and role, experienced professionals may progress into staff or principal data scientist positions, analytics leadership, or specialized AI and machine learning roles. Browse Ladders for vetted openings paying $100,000 or more.
Use Ladders to explore opportunities aligned with your expertise and career ambitions. Review each listing for responsibilities, qualifications, location, and compensation details, then apply to roles that fit your goals.
Principal Data Scientist - DDSAI GD
$117K - $201K *
Lead the charge in delivering integrated analytical solutions for clinical development, leveraging ML, GenAI, and RWD to drive impactful outcomes across diverse stakeholder groups in a dynamic environ...
Yesterday
$155K - $211K *
Lead the charge in developing innovative data solutions that enhance business workflows and drive automation, collaborating with cross-functional teams to translate requirements into actionable insigh...
Reposted 2 weeks ago
$150K - $185K *
Lead the development of innovative AI products that empower job seekers with evidence-based coaching and actionable insights, while collaborating closely with cross-functional teams to shape impactful...
3 weeks ago
$190K - $245K *
Champion AI innovation by developing cutting-edge models that analyze real-time global data, enhancing threat intelligence and risk assessment. Collaborate with a diverse team to drive impactful solut...
1 week ago
$190K - $245K *
Transform real-time AI research into impactful solutions by developing advanced models and systems that analyze global data, enhancing threat intelligence and decision-making for organizations worldwi...
1 week ago
Senior Applied Scientist II, Ads Optimization
$240K - $253K *
Pioneer innovation in real-time bid optimization systems, driving advertising performance by turning complex mathematical insights into robust production code. Lead cross-functional initiatives to max...
Reposted today
$120K - $145K *
Join a team that's building a robust data foundation and AI services. You'll design and operate data pipelines, deploy on AWS, and collaborate with business teams to deliver impactful solutions that e...
3 days ago
Senior Data Scientist (AI-assisted Clinical Development)
$142K - $264K *
Bring your expertise to drive AI/ML-powered digital solutions that transform medicine development. Collaborate across teams to build innovative tools, ensuring ethical impact and compliance in a regul...
Reposted 1 week ago
$130K - $196K *
Analyze and lead statistical design across the product lifecycle, collaborating with cross-functional teams to define objectives and strategies. Drive evidence generation from diverse datasets while e...
3 weeks ago
Senior People Analytics Engineer
$101K - $161K *
Drive your career forward by leading advanced People Analytics initiatives. Collaborate across teams to transform complex data into actionable insights, enhancing workforce decision-making and shaping...
3 days ago
$141K - $236K *
Shape the future of national security by driving innovative data solutions and analytics. Collaborate with experts to transition prototypes into production, delivering impactful insights while integra...
Today
$114K - $190K *
Engineer data-driven solutions to enhance Marine Corps mission capabilities through rigorous analysis, modeling, and simulation. Collaborate with cross-functional teams to deliver actionable insights...
1 week ago
$67K - $112K *
Transform complex data into actionable insights by developing predictive models and analytics solutions for financial services clients. Collaborate with stakeholders to drive business value through ad...
Reposted 3 weeks ago
$130K - $196K *
Shape the future of healthcare by leading statistical design and analysis across product lifecycles. Collaborate with cross-functional teams to drive evidence generation and ensure scientific integrit...
3 weeks ago
$135K - $160K *
Transform data landscapes by designing and maintaining scalable data pipelines using Azure services, Python, and Spark. Collaborate with cross-functional teams to deliver reliable data solutions that...
2 weeks ago
$130K - $196K *
Unlock potential by leading statistical design and analysis throughout the product lifecycle. Collaborate cross-functionally to define objectives and strategies, ensuring scientific integrity and effe...
3 weeks ago
$130K - $196K *
Unlock the potential of data by leading statistical design and analysis across the product lifecycle. Collaborate with cross-functional teams to drive evidence generation and ensure scientific integri...
3 weeks ago
$130K - $196K *
Unlock potential by leading statistical design and analysis throughout the product lifecycle, collaborating with cross-functional teams to ensure scientific integrity and effective decision-making usi...
3 weeks ago
$130K - $196K *
Engage with cross-functional teams to lead statistical design and analysis throughout the product lifecycle, ensuring scientific integrity and effective decision-making using diverse data sources...
3 weeks ago
$130K - $196K *
Drive statistical leadership across the product lifecycle, collaborating with cross-functional teams to define objectives and analysis strategies. Ensure scientific integrity and provide actionable in...
3 weeks ago
Senior Principal Scientist, Data Science - R&D DDSAI - Therapeutics Development & Supply (TDS)
$137K - $235K *
Elevate decision-making by leading the development of Operations Research and Decision Intelligence solutions. Collaborate with senior stakeholders to enhance forecasting, optimization, and simulation...
2 days ago
Senior Principal Scientist, Data Science - R&D DDSAI - Therapeutics Development & Supply (TDS)
$137K - $235K *
Join a team that's redefining decision intelligence in pharmaceutical R&D. Lead the development of advanced modeling solutions, collaborating with senior stakeholders to enhance operational efficiency...
2 days ago
Senior Principal Scientist, Data Science - R&D DDSAI - Therapeutics Development & Supply (TDS)
$137K - $235K *
Drive innovation in data science by developing advanced decision-support models that enhance operational efficiency and strategic planning across therapeutic development and supply chains, collaborati...
2 days ago
$120K - $145K *
Transform data into actionable insights by applying advanced analytics and machine learning techniques to enhance traffic and revenue forecasting, customer behavior analysis, and business performance...
3 days ago
$67K - $112K *
Join a team that's transforming financial services through advanced analytics. Collaborate with cross-functional teams to deliver predictive models and insights, driving value for clients while managi...
Today
What does a Senior Data Scientist do?
A Senior Data Scientist uses statistics, programming, and machine learning to analyze data, develop models, and inform business or product decisions. The role often includes collaborating across teams and mentoring other data professionals.
What qualifications are common for Senior Data Scientist jobs?
Employers commonly seek substantial data science experience, proficiency in Python or R and SQL, knowledge of statistical methods and machine learning, and the ability to communicate insights. Requirements vary by company and industry.
What industries hire Senior Data Scientists?
Senior Data Scientists work in technology, financial services, healthcare, retail, consulting, and many other industries that use data to improve products, operations, or decision-making.
How can I find Senior Data Scientist jobs paying $100,000 or more?
Browse vetted Senior Data Scientist listings on Ladders and review compensation, qualifications, and responsibilities to find opportunities aligned with your experience and career goals.