Explore senior data scientist opportunities with organizations seeking experienced professionals to turn complex data into meaningful business results. Ladders features vetted jobs paying $100,000 or more, helping you focus your search on roles that match your skills, leadership experience, and compensation goals.
Senior data scientists design analytical approaches, build and evaluate statistical and machine learning models, and translate findings into practical recommendations. They work with product, engineering, business, and executive teams to identify opportunities, guide decisions, and deliver data-driven solutions.
Employers often look for advanced experience in Python or R, SQL, statistical analysis, machine learning, experimentation, and data visualization. Senior candidates may also bring expertise in cloud platforms, large-scale data systems, model deployment, and responsible AI. Clear communication, sound judgment, and the ability to mentor teammates are also valuable.
Senior data scientists can find opportunities across technology, finance, healthcare, retail, consulting, and other data-intensive industries. Depending on the organization and role, experienced professionals may progress into staff or principal data scientist positions, analytics leadership, or specialized AI and machine learning roles. Browse Ladders for vetted openings paying $100,000 or more.
Use Ladders to explore opportunities aligned with your expertise and career ambitions. Review each listing for responsibilities, qualifications, location, and compensation details, then apply to roles that fit your goals.
$110K - $130K *
Transform raw legal and medical data into impactful machine learning models. Collaborate with experts to enhance our proprietary platform using ML, NLP, and generative AI, driving measurable improveme...
1 week ago
$135K - $160K *
Join our dynamic ML team to develop and deploy cutting-edge models that enhance our proprietary claims-intelligence platform, focusing on machine learning, NLP, and generative AI to improve outcomes f...
1 week ago
$100K - $145K *
Inspire innovation in vaccine development by leveraging data science to create predictive models and monitoring tools that enhance manufacturing processes and product quality across multidisciplinary...
Today
Senior/Sr. Staff AI Infrastructure Engineer, Inference & Optimization
$169K - $351K *
Advance your career by optimizing and deploying AI models in cutting-edge infrastructures that bridge deep learning algorithms and real-time autonomous systems, ensuring ultra-low latency and operatio...
Reposted 3 weeks ago
Principal Scientist, Data Science (Data Products, Integration & Analysis)
$117K - $201K *
Join a team that develops AI-enabled scientific data products, shaping data strategies for drug discovery and patient safety. You'll design scalable integration frameworks, enhance data architectures...
Reposted 1 week ago
Principal Scientist, Data Science (Data Products, Integration & Analysis)
$117K - $201K *
Accelerate progress at the forefront of scientific data engineering, combining expertise in AI and data architecture to design interoperable, AI-ready data solutions that drive drug discovery and deve...
Reposted 1 week ago
Principal Scientist, Data Science (Data Products, Integration & Analysis)
$117K - $201K *
Lead the development of innovative scientific data products to enhance AI-driven drug discovery efforts, ensuring effective integration across diverse data domains to support patient safety and transl...
Reposted 1 week ago
Principal Scientist, Data Science (Data Products, Integration & Analysis)
$117K - $201K *
Shape the future of drug discovery by leading the design and implementation of AI-ready scientific data products that enhance drug development and patient safety through innovative data architectures...
Reposted 1 week ago
Principal Scientist, Data Science (Data Products, Integration & Analysis)
$117K - $201K *
Drive the evolution of AI-ready scientific data products that integrate and enhance the drug discovery and development lifecycle, fostering collaboration between multiple scientific domains and ensuri...
Reposted 1 week ago
Principal Data Scientist - AI, Machine Learning, Fraud Detection
$135K - $160K *
Shape the future of data science by leading advanced ML initiatives that drive strategic business outcomes. Collaborate cross-functionally to tackle high-impact challenges in fraud detection and risk...
2 weeks ago
Senior Machine Learning Engineer, Fulfillment
$173K - $182K *
Lead the charge in designing and deploying impactful machine learning systems. Collaborate across teams to drive innovation and improve business outcomes in a fast-paced environment, leveraging your e...
Yesterday
Senior Machine Learning Engineer, Fulfillment
$180K - $190K *
Unlock potential by designing and deploying impactful machine learning systems. Collaborate across teams to enhance grocery industry solutions, ensuring scalable and reliable software that drives meas...
Yesterday
$175K - $215K *
Drive the development of analytics data products, transforming prototypes into trusted, production-grade models. Collaborate with internal teams to ensure data integrity and deliver actionable insight...
3 weeks ago
$131K - $237K *
Unlock potential by transforming complex data into actionable insights that drive mission-critical decisions. Join a dynamic team to lead innovative data science solutions for the Intelligence Communi...
2 weeks ago
$131K - $237K *
Champion innovative data solutions that drive mission-critical decisions. Lead the design and operationalization of advanced analytics and AI/ML capabilities, collaborating with cross-functional teams...
2 weeks ago
$131K - $237K *
Lead the charge in transforming complex data into actionable insights that drive mission-critical decisions. Collaborate with cross-functional teams to develop innovative data science solutions that e...
2 weeks ago
$131K - $237K *
Empower mission success by transforming complex data into actionable insights. Lead the design and operationalization of advanced data science capabilities, collaborating with cross-functional teams t...
2 weeks ago
$131K - $237K *
Unlock potential by leading data science initiatives that drive mission-critical insights. Collaborate with cross-functional teams to develop innovative AI/ML solutions, transforming complex datasets...
2 weeks ago
Senior Machine Learning Engineer, Cosmos Engineering
$184K - $356K *
Shape the future of intelligent video analytics by building state-of-the-art AI solutions. Engage with cross-functional teams and drive innovation in deep learning applications for smart cities and in...
Reposted yesterday
$131K - $237K *
Lead the charge in transforming complex data into actionable insights that drive mission-critical decisions. Collaborate with cross-functional teams to develop innovative data science solutions that e...
2 weeks ago
Sr. Data Scientist, Performance Marketing
$139K - $287K *
Analyze complex data to drive marketing strategies and user growth. Collaborate with cross-functional teams to develop statistical models and optimize performance marketing efforts, influencing key bu...
3 days ago
Sr. Data Scientist, Performance Marketing
$139K - $287K *
Unlock potential by leveraging advanced analytics to drive user growth and optimize marketing strategies. Collaborate with cross-functional teams to translate data insights into actionable recommendat...
3 days ago
Applied Data Scientist - AI Enablement (Transportation)
$95K - $115K *
Join a dynamic team to develop AI solutions and improve internal capabilities within the Transportation Business Group, progressing from internal development to client-facing delivery and advisory wor...
Reposted 2 weeks ago
$127K - $236K *
Champion advanced analytics and AI solutions to enhance underwriting decisions. Lead complex data science projects, mentor teams, and collaborate with stakeholders to deliver impactful, scalable solut...
3 weeks ago
$127K - $236K *
Unlock potential by leading data science initiatives that enhance underwriting decisions and drive automation. Collaborate with cross-functional teams to develop and implement advanced analytics solut...
3 weeks ago
What does a Senior Data Scientist do?
A Senior Data Scientist uses statistics, programming, and machine learning to analyze data, develop models, and inform business or product decisions. The role often includes collaborating across teams and mentoring other data professionals.
What qualifications are common for Senior Data Scientist jobs?
Employers commonly seek substantial data science experience, proficiency in Python or R and SQL, knowledge of statistical methods and machine learning, and the ability to communicate insights. Requirements vary by company and industry.
What industries hire Senior Data Scientists?
Senior Data Scientists work in technology, financial services, healthcare, retail, consulting, and many other industries that use data to improve products, operations, or decision-making.
How can I find Senior Data Scientist jobs paying $100,000 or more?
Browse vetted Senior Data Scientist listings on Ladders and review compensation, qualifications, and responsibilities to find opportunities aligned with your experience and career goals.