Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Director, Medical Science Liaisons-Oncology
$221K - $368K *
Join a team that's dedicated to advancing oncology through leadership and collaboration. Drive strategic initiatives, mentor a high-performing team, and ensure compliance while fostering a culture of...
1 week ago
$93K - $110K *
Join a team that's dedicated to delivering exceptional project management for restaurant construction. Oversee projects from inception to completion, ensuring client satisfaction and adherence to time...
2 days ago
Edge Strategist Senior Consultant
$128K - $252K *
Shape AI strategies by conducting stakeholder interviews, prioritizing use cases, and collaborating with teams to develop AI-enabled solutions that drive business value and transformation...
Today
Edge Strategist Senior Consultant
$128K - $252K *
Unlock potential by leading AI strategy initiatives that drive business transformation. Collaborate with stakeholders to identify needs, prioritize use cases, and develop actionable roadmaps for AI ad...
Today
$80K - $95K *
Lead our Rehab Team to enhance the lives of older adults by supervising staff, managing therapy activities, and ensuring optimal patient outcomes in a collaborative environment...
2 days ago
$80K - $120K *
Lead a diverse portfolio of clients as a Tax Manager, overseeing compliance and planning while mentoring your team. Enjoy autonomy in client relationships and contribute to a culture of high-quality s...
Reposted today
$138K - $190K *
Advance solutions in behavioral health by leveraging technical expertise to drive sales success. Collaborate with teams to deliver tailored demonstrations, support RFPs, and align strategies with clie...
3 days ago
Associate Director, Client Media Solutions
$100K - $115K *
Champion integrated media strategies for pharmaceutical clients, driving engagement and measurable outcomes. Lead cross-functional teams to develop innovative solutions that address complex healthcare...
Today
Senior Business Intelligence Analyst - Enterprise Analytics
$90K - $115K *
Lead the charge in transforming complex business needs into impactful analytic products. Collaborate with stakeholders to design, develop, and maintain reusable semantic models that enhance decision-m...
1 week ago
$107K - $172K *
Shape the future of cash management by enhancing forecasting capabilities and providing critical insights for strategic decision-making, operational planning, and capital allocation in a dynamic envir...
Reposted 4 weeks ago
Enterprise Account Executive (Founding Team)
$250K - $280K *
Shape the future of our enterprise sales segment by driving growth and account success. Take ownership of new logo acquisitions, deepen existing client relationships, and establish best practices for...
Reposted 3 weeks ago
Senior Product Manager - Payments
$137K - $186K *
Join our dynamic FinTech team as a Senior Product Manager, leading strategy, and execution to shape payment solutions. Leverage your product management expertise to drive growth and enhance customer e...
Reposted 1 week ago
Senior Partner Marketing Manager
$110K - $130K *
Engage with top-tier partners to define and execute innovative co-marketing strategies that amplify AI-driven growth. Oversee the entire partner marketing roadmap, ensuring measurable impact on pipeli...
Reposted 3 weeks ago
Principal Services Sales Consultant
$110K - $130K *
Unlock potential by leading tailored service solutions that drive client success. Collaborate with stakeholders to strategize and execute sales plans, ensuring exceptional engagement and delivering va...
Reposted 2 weeks ago
$93K - $125K *
Join a dynamic team as a technical resource, enhancing enterprise applications and infrastructure services. Drive operational excellence, support cross-functional initiatives, and ensure reliable, sec...
2 weeks ago
Senior Vice President, Growth & Commercialization
$210K - $250K *
Lead a dynamic team to drive growth and commercialization strategies, enhancing market presence and client acquisition. Collaborate cross-functionally to transform insights into actionable plans, ensu...
5 days ago
Account Director, Global Strategic Accounts
$175K - $215K *
Shape the future of global partnerships by leading strategic account management, driving growth, and fostering executive relationships. Oversee program success and team leadership to deliver exception...
3 weeks ago
Associate Director - Reinsurance Claims
$100K - $120K *
Transform client relationships by managing reinsurance claims, ensuring accuracy and compliance while collaborating with brokers and reinsurers to deliver exceptional service and support across multip...
5 days ago
Senior Economic Analyst - Corporate Marketing - Market Insights (Kansas City)
$110K - $130K *
Unlock strategic insights by analyzing global and local economic trends to drive decision-making across teams. Collaborate with business development and finance to identify growth opportunities and ma...
2 weeks ago
Business Development Manager, Systems
$110K - $130K *
Drive new revenue growth by identifying and converting business opportunities, building executive relationships, and leading complex sales processes in a competitive landscape. Engage with customers t...
2 weeks ago
$165K - $195K *
Engage in strategic solution development for Federal Government initiatives, translating client needs into innovative technical strategies. Collaborate with cross-functional teams to deliver compellin...
1 week ago
Senior Consultant 1, Analytics
$80K - $100K *
Transform your career with this client-facing role, leveraging your expertise in analytics tools like Google Analytics and Tag Manager to deliver strategic solutions and enhance data-driven decision-m...
Reposted 2 weeks ago
$150K - $266K *
Transform mortality analytics by leading actuarial assumption modeling, translating complex insights into competitive strategies. Collaborate with cross-functional teams to enhance product offerings a...
Reposted today
Portfolio Mgr Senior-Commercial
$141K - $207K *
Engage in strategic portfolio management, collaborating with loan officers to oversee complex commercial banking relationships, assess credit risk, and identify growth opportunities while ensuring com...
2 weeks ago
Associate Director, Clinical Trial Management - Full-Service
$120K - $150K *
Elevate your career by leading clinical trial management teams, ensuring quality and compliance in monitoring strategies. Collaborate with cross-functional teams to optimize clinical operations and dr...
1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.