Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$90K - $115K *
Join a dynamic team as a Senior Project Planner, driving financial health and vendor coordination across multiple brands while ensuring project success through strategic planning and effective communi...
1 week ago
Senior Director, Head of Research & Early Development
$228K - $342K *
Empower your career by leading strategic project management initiatives across early drug development. Drive process optimization, cultivate high-performing teams, and collaborate with executives to a...
5 days ago
Licensed Life Insurance Sales Agent
$70K - $200K *
The Licensed Life Insurance Sales Agent will guide customers through the life insurance buying process, educating them on products and ensuring a transparent experience. This role involves engaging wi...
Reposted today
$92K - $98K *
Partner with us to drive impactful federal proposals, managing the lifecycle from analysis to submission. Collaborate with diverse teams to create compliant, compelling proposals that align with strat...
2 weeks ago
$115K - $135K *
Join a team that's driving enterprise growth by identifying new business opportunities and forming strategic relationships. You'll navigate complex sales cycles and engage with senior leaders to tailo...
Reposted 1 week ago
General Manager, Collibra Public Sector
$150K - $180K *
Lead the charge in executing strategic initiatives for a public sector subsidiary to ensure profitable growth, optimizing team performance, and aligning operations with government mandates and market...
Reposted 2 days ago
Senior Customer Success Engineer
$95K - $171K *
Transform client success by delivering tailored support and strategic insights, ensuring seamless onboarding and ongoing engagement with our innovative platform. Leverage your expertise in energy engi...
4 days ago
$85K - $100K *
Join our dynamic team to analyze and enhance ACO performance in Medicare VBC programs. Leverage your expertise in data analytics to drive insights, track KPIs, and support data-driven decision-making...
4 days ago
$175K - $195K *
Unlock potential by leading strategic M&A initiatives across Europe and APAC. Drive deal execution with autonomy, manage due diligence, and collaborate with senior leadership to shape investment strat...
4 days ago
$100K - $120K *
Champion growth by managing diverse banking and retail accounts, leveraging your sales expertise to uncover opportunities and enhance customer solutions while collaborating across teams to drive resul...
1 week ago
$130K - $150K *
Join a dynamic team to design and develop innovative mobile solutions across Android and iOS. Take ownership of projects, collaborate with peers, and contribute to the broader tech stack while enhanci...
6 days ago
$80K - $95K *
Drive the Arbitration Team's success by leading initiatives that enhance performance, streamline processes, and foster client relationships. Oversee daily operations and ensure exceptional service del...
4 weeks ago
$100K - $120K *
Execute comprehensive program management for a critical Air Force contract, leading a diverse team to ensure compliance, quality, and performance across multiple global operations while maintaining 24...
1 week ago
Director, Analyst, Workday Contract Negotiations & Licensing
$148K - $175K *
Unlock your potential as a Director, leveraging insights and expertise to guide clients in navigating complex SaaS negotiations and market trends, while driving impactful strategies that enhance busin...
2 weeks ago
Senior NetSuite Solution Architect
$180K - $240K *
Transform client operations by leading the design and implementation of scalable NetSuite ERP solutions. Collaborate with stakeholders to optimize processes, enhance system adoption, and drive continu...
4 weeks ago
Associate Director, Principal Medical Writer II
$120K - $145K *
Elevate your career by leading the development of high-quality clinical documents for global regulatory submissions. Collaborate with cross-functional teams to ensure data-driven messaging aligns with...
5 days ago
Principal Consultant, Environmental FERC Project Manager
$110K - $130K *
Drive strategic leadership for complex energy projects, ensuring compliance and stakeholder engagement while managing multi-site environmental permitting and regulatory processes across the U.S. Lead...
1 week ago
Business Development Director I, Early Drug Development
$80K - $120K *
Shape the future of Crop Protection & Chemicals by driving sales and fostering client relationships. Utilize strategic insights and collaboration to achieve targets and expand market presence while ma...
Reposted 1 week ago
Senior National Account Executive, Enterprise Technology Partnerships
$120K - $140K *
Unlock your potential by leading enterprise sales for our innovative technology, driving strategic partnerships with large corporate insurance agencies and institutions. Own the sales cycle, navigate...
2 weeks ago
1557- Director, Strategic Sourcing- Corporate Services
$125K - $185K *
Transform strategic sourcing for HR and Benefits, leading complex engagements and driving cost savings while ensuring high supplier performance and stakeholder satisfaction across diverse client needs...
2 weeks ago
Cultural Resources/Architectural Historian and Senior Project Manager
$135K - $155K *
Join a team that's shaping the future of cultural resources management. As a Senior Project Manager, you'll lead initiatives, mentor staff, and collaborate with experts to enhance our services across...
Today
$115K - $136K *
Innovate by driving new business opportunities with executive finance leaders. Leverage your consultative sales skills to deliver transformative SaaS solutions, ensuring measurable outcomes and buildi...
3 weeks ago
VP - Global Strategic Partnerships
$190K - $381K *
Empower global partnerships by leading strategy and execution across markets, enhancing relationships with key partners, and driving innovation in financial services. Build a high-performing team to s...
3 weeks ago
Associate Vice President of Philanthropy
$115K *
Lead a dynamic team to enhance donor engagement and drive fundraising strategies. Oversee major gift initiatives while fostering a culture of mentorship and accountability. Collaborate with leadership...
Today
Associate Vice President of Philanthropy
$115K *
Lead the charge in cultivating a donor-centered culture while managing a high-performing team. Drive strategic fundraising initiatives and engage with key stakeholders to secure major gifts and enhanc...
6 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.