Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Supervisory Criminal Investigator (Special Agent in Charge) Temp NTE 1 Year, MBE 2 years, MBMP
$100K - $120K *
Lead strategic planning and execution of investigative programs, ensuring alignment with organizational goals. Oversee multiple teams, manage resources, and provide expert guidance on law enforcement...
1 week ago
Supervisory Criminal Investigator (Special Agent in Charge) Temp NTE 1 Year, MBE 2 years, MBMP
$100K - $120K *
Lead strategic planning and execution of criminal investigations, ensuring compliance with IRS objectives. Oversee subordinate units, manage resources, and advise on legal matters to enhance operation...
1 week ago
Life Sciences Commercial, Management Consulting Principal Director
$150K - $375K *
Join a team that's transforming life sciences through strategic commercial leadership. Drive large-scale engagements, foster client relationships, and deliver innovative solutions that enhance operati...
2 weeks ago
Behavioral Health Medical Director
$215K - $408K *
Drive medical management and quality improvement initiatives, ensuring effective utilization and cost containment while collaborating with clinical teams to enhance patient care and outcomes across mu...
Today
Behavioral Health Medical Director
$215K - $408K *
Grow your career with a dynamic role in behavioral health, leading medical management and quality improvement initiatives. Collaborate across diverse markets to enhance care delivery and support conti...
Today
Behavioral Health Medical Director
$215K - $408K *
Drive medical leadership in quality improvement and utilization management, ensuring effective care delivery and cost containment. Collaborate with clinical teams to enhance patient outcomes and suppo...
5 days ago
$150K - $183K *
Join a team that's driving growth by acquiring and managing Mid-Market accounts. You'll identify prospects, manage the sales cycle, and build lasting relationships to exceed revenue targets in a dynam...
Reposted today
$180K - $220K *
Lead the global Accounting and Treasury function, driving financial systems, reporting, and IPO readiness while building a scalable team to support international growth and operational complexity...
1 week ago
Senior Risk Program Manager - Fraud & Disputes Enablement
$138K - $173K *
Transform the future of banking by leading program management for Bank Charter Readiness. Collaborate across teams to enhance fraud, disputes, and risk operations, utilizing data-driven insights for c...
3 weeks ago
$150K - $170K *
Partner with us to drive growth and strengthen relationships with key strategic accounts. Leverage your expertise in enterprise sales to identify opportunities, ensure renewals, and deliver measurable...
4 weeks ago
Senior Analyst, Fraud Intelligence
$125K - $145K *
Analyze and uncover fraud patterns using large-scale data to enhance protection strategies. Collaborate with cross-functional teams to develop insights and solutions that directly impact fraud prevent...
2 weeks ago
Senior Business Development Specialist
$95K - $135K *
Optimize business operations by providing strategic project support to senior leadership, enhancing recruitment processes, and analyzing market data to drive informed decision-making and improve captu...
1 week ago
$100K - $120K *
Empower Public Safety agencies by driving sales and fostering relationships across a multi-state territory. Manage the sales cycle through consultative partnerships, ensuring pipeline growth and reven...
Reposted 3 weeks ago
Senior Sales Executive - State & Local Government
$140K - $180K *
Champion growth by leveraging your consultative sales expertise to secure contracts and enhance client relationships in the public sector, specifically within Medicaid and Human Services programs. Dri...
2 weeks ago
Administrative Director of BEHAVIORAL HEALTH SERVICE LINE
$140K - $160K *
Drive operational excellence and strategic growth in behavioral health services, ensuring patient-centered care and compliance. Collaborate with leadership to enhance quality, access, and financial pe...
3 weeks ago
Senior Consultant - Finance ERP Focus
$125K - $140K *
Shape the future of ERP and Finance transformation by guiding clients through strategic assessments, technology alignment, and impactful change initiatives. Leverage your expertise to foster strong re...
4 weeks ago
Principal Delivery Manager, Portfolio
$145K - $188K *
Elevate delivery excellence by shaping strategies for Portfolio Management, ensuring seamless execution across teams while adapting to evolving technologies and processes. Lead the charge in establish...
3 weeks ago
Sr. Counsel, Compliance & Investigations
$158K - $326K *
Drive compliance excellence by managing investigations, enhancing policies, and collaborating with cross-functional teams to uphold ethical standards and legal requirements in a dynamic environment...
3 weeks ago
$125K - $150K *
Shape the future of affordable housing by managing LIHTC transactions from underwriting to closing. Collaborate with developers and investors to ensure timely execution and sound investment recommenda...
2 days ago
Senior Life & Annuity Product Accountant
$91K - $169K *
Transform complex accounting challenges into strategic solutions. Collaborate across finance, actuarial, and risk teams to enhance financial reporting and governance for innovative products and transa...
3 weeks ago
$110K - $150K *
Transform treasury operations by building infrastructure for international and commercial expansion, managing complex cash flows, overseeing debt compliance, and enhancing banking relationships, while...
Reposted today
Director, Consulting & Advisory Alliances, North America
$150K - $170K *
Join a team that's expanding strategic partnerships with consulting firms to enhance supply chain solutions. Drive growth through collaboration, relationship management, and innovative go-to-market st...
5 days ago
Associate Director, Scheduling- Civil Infrastructure Construction
$175K - $220K *
Join a team that's shaping infrastructure projects through expert scheduling leadership. Your strategic planning and risk management skills will optimize resource use and ensure timely delivery in a c...
Reposted 1 week ago
Senior Compliance Analyst (Compliance Oversight Activities) - Remote
$74K - $118K *
Elevate compliance standards by leading oversight initiatives, managing complex projects, and collaborating across teams to ensure regulatory adherence and effective governance in a dynamic environmen...
1 week ago
Analytics Advisor III (R-19951)
$110K - $130K *
Unlock potential by driving analytics and AI solutions for clients, managing a $10M+ portfolio. Collaborate with sales teams to identify opportunities, build value stories, and achieve aggressive sale...
2 weeks ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.