Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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1,000+

Senior Counsel Jobs in Missouri

Sort By: Relevance

$100K - $120K *

Lead strategic planning and execution of investigative programs, ensuring alignment with organizational goals. Oversee multiple teams, manage resources, and provide expert guidance on law enforcement...

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$100K - $120K *

Lead strategic planning and execution of criminal investigations, ensuring compliance with IRS objectives. Oversee subordinate units, manage resources, and advise on legal matters to enhance operation...

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$150K - $375K *

Join a team that's transforming life sciences through strategic commercial leadership. Drive large-scale engagements, foster client relationships, and deliver innovative solutions that enhance operati...

2 weeks ago

  •   11 - 15 years exp.  •   Business Services

$215K - $408K *

Drive medical management and quality improvement initiatives, ensuring effective utilization and cost containment while collaborating with clinical teams to enhance patient care and outcomes across mu...

RemoteRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$215K - $408K *

Grow your career with a dynamic role in behavioral health, leading medical management and quality improvement initiatives. Collaborate across diverse markets to enhance care delivery and support conti...

Missouri, USRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$215K - $408K *

Drive medical leadership in quality improvement and utilization management, ensuring effective care delivery and cost containment. Collaborate with clinical teams to enhance patient outcomes and suppo...

RemoteRemote

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $183K *

Join a team that's driving growth by acquiring and managing Mid-Market accounts. You'll identify prospects, manage the sales cycle, and build lasting relationships to exceed revenue targets in a dynam...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Business Services

$180K - $220K *

Lead the global Accounting and Treasury function, driving financial systems, reporting, and IPO readiness while building a scalable team to support international growth and operational complexity...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Healthcare

$138K - $173K *

Transform the future of banking by leading program management for Bank Charter Readiness. Collaborate across teams to enhance fraud, disputes, and risk operations, utilizing data-driven insights for c...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$150K - $170K *

Partner with us to drive growth and strengthen relationships with key strategic accounts. Leverage your expertise in enterprise sales to identify opportunities, ensure renewals, and deliver measurable...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$125K - $145K *

Analyze and uncover fraud patterns using large-scale data to enhance protection strategies. Collaborate with cross-functional teams to develop insights and solutions that directly impact fraud prevent...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$95K - $135K *

Optimize business operations by providing strategic project support to senior leadership, enhancing recruitment processes, and analyzing market data to drive informed decision-making and improve captu...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Business Services

$100K - $120K *

Empower Public Safety agencies by driving sales and fostering relationships across a multi-state territory. Manage the sales cycle through consultative partnerships, ensuring pipeline growth and reven...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$140K - $180K *

Champion growth by leveraging your consultative sales expertise to secure contracts and enhance client relationships in the public sector, specifically within Medicaid and Human Services programs. Dri...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Business Services

$140K - $160K *

Drive operational excellence and strategic growth in behavioral health services, ensuring patient-centered care and compliance. Collaborate with leadership to enhance quality, access, and financial pe...

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$125K - $140K *

Shape the future of ERP and Finance transformation by guiding clients through strategic assessments, technology alignment, and impactful change initiatives. Leverage your expertise to foster strong re...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$145K - $188K *

Elevate delivery excellence by shaping strategies for Portfolio Management, ensuring seamless execution across teams while adapting to evolving technologies and processes. Lead the charge in establish...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$158K - $326K *

Drive compliance excellence by managing investigations, enhancing policies, and collaborating with cross-functional teams to uphold ethical standards and legal requirements in a dynamic environment...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$125K - $150K *

Shape the future of affordable housing by managing LIHTC transactions from underwriting to closing. Collaborate with developers and investors to ensure timely execution and sound investment recommenda...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$91K - $169K *

Transform complex accounting challenges into strategic solutions. Collaborate across finance, actuarial, and risk teams to enhance financial reporting and governance for innovative products and transa...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $150K *

Transform treasury operations by building infrastructure for international and commercial expansion, managing complex cash flows, overseeing debt compliance, and enhancing banking relationships, while...

RemoteRemote

Reposted today

  •   8 - 10 years exp.  •   Healthcare

$150K - $170K *

Join a team that's expanding strategic partnerships with consulting firms to enhance supply chain solutions. Drive growth through collaboration, relationship management, and innovative go-to-market st...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Information Technology

$175K - $220K *

Join a team that's shaping infrastructure projects through expert scheduling leadership. Your strategic planning and risk management skills will optimize resource use and ensure timely delivery in a c...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$74K - $118K *

Elevate compliance standards by leading oversight initiatives, managing complex projects, and collaborating across teams to ensure regulatory adherence and effective governance in a dynamic environmen...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Unlock potential by driving analytics and AI solutions for clients, managing a $10M+ portfolio. Collaborate with sales teams to identify opportunities, build value stories, and achieve aggressive sale...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.