Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Private Equity Fund Accounting & Administration, Officer
$70K - $107K *
Champion client relationships and lead a team in fund accounting, ensuring timely deliverables and compliance. Oversee financial reviews, audits, and complex calculations while thriving in a dynamic...
Reposted 1 week ago
Sr. Customer Development Executive
$171K - $236K *
Drive customer success by managing relationships, identifying upsell opportunities, and collaborating with teams to ensure long-term growth and satisfaction for existing clients, focusing on measurabl...
3 days ago
Senior Customer Success Manager
$90K - $100K *
Empower enterprise clients by maximizing the value of marketing technology solutions. Drive customer engagement and retention through strategic partnerships, data-driven insights, and effective campai...
4 days ago
Executive Administrative Partner
$90K - $105K *
Partner with us to provide exceptional administrative support to a VP, managing complex calendars, travel logistics, and cross-functional relationships while ensuring smooth operations and effective c...
3 weeks ago
Enterprise Applications Architect
$116K - $155K *
Transform enterprise applications through strategic architecture, integration, and governance. Collaborate with stakeholders to enhance business processes and ensure reliable operation of platforms wh...
Today
SAP Sales and Service Cloud Lead Architect
$134K - $265K *
Shape the future of client solutions by leading complex SAP Sales and Service Cloud integrations. Utilize your expertise to define architecture, guide teams, and drive impactful transformations in a d...
2 weeks ago
SAP Sales and Service Cloud Lead Architect
$134K - $265K *
Transform complex application components and integrations as a Lead Architect. Leverage your SAP expertise to define solutions, guide architecture, and drive successful implementations while collabora...
2 weeks ago
Associate Medical Director (Promotional Medical Education)
$100K - $125K *
Manage a team of medical writers to develop impactful scientific content, ensuring accuracy and compliance. Collaborate with clients and cross-functional teams to drive medical strategies and delivera...
Reposted 2 weeks ago
$90K - $110K *
Elevate workforce management by leading forecasting, capacity planning, and real-time optimization across teams and BPO partners. Drive efficiency and performance using data and technology while devel...
4 weeks ago
$100K - $115K *
Champion revenue growth by leading strategic sales initiatives in K-12 districts. Build executive relationships, drive consultative sales, and influence assessment strategies to align solutions with d...
Reposted today
Sr. / Principal Medical Writer (Regulatory focus) - Sponsor-dedicated; NA/CAN/UK
$110K - $130K *
Advance your career by leading medical writing projects in a regulatory environment. Collaborate with cross-functional teams to produce high-quality documents, ensuring compliance with industry standa...
1 week ago
Sr. / Principal Medical Writer (Regulatory focus) - Sponsor-dedicated; NA/CAN/UK
$80K - $175K *
Champion the creation of high-quality regulatory documents, managing writing tasks and leading reviews. Collaborate across teams to ensure clarity and compliance, mentoring junior writers while delive...
Reposted 2 weeks ago
$180K - $220K *
Unlock your potential as a senior leader in tax services, driving strategic direction and client relationships while ensuring compliance and quality. Mentor future leaders and contribute to practice g...
2 weeks ago
Principal Consultant - Utility Prudence Expert
$200K - $240K *
Champion the future of energy by providing expert consulting on utility prudence, managing client engagements, and delivering impactful testimony on modernization and rate cases. Collaborate with team...
1 week ago
Senior Principal - Business Consulting
$210K - $256K *
Unlock potential by leading Oracle Order Management transformations, driving solution design, and guiding global implementations. Leverage your extensive SCM expertise to mentor teams and engage with...
4 days ago
Senior Principal - Business Consulting
$280K - $406K *
Drive transformation in the semiconductor sector by leading client engagements, developing solutions, and mentoring teams. Collaborate with senior leadership to enhance operational models and deliver...
5 days ago
$150K - $185K *
Shape strategic success for key accounts by leading market access initiatives, collaborating with cross-functional teams, and driving growth through innovative solutions and insights in the managed ma...
3 weeks ago
$189K - $247K *
Empower inventory excellence by optimizing forecasting and replenishment strategies to enhance performance and drive ROI. Collaborate across teams to create data-driven solutions for rapid growth and...
Reposted today
Associate Director, Operational Excellence
$110K - $130K *
Lead operational excellence initiatives by collaborating with site leadership to enhance performance, drive continuous improvement, and ensure compliance. Foster a culture of safety and quality while...
4 weeks ago
$95K - $113K *
Manage project lifecycles to exceed client expectations, ensuring timely communication and risk management while fostering collaboration and mentoring within teams to achieve project goals and profita...
1 week ago
$95K - $113K *
Manage project lifecycles to exceed client expectations, ensuring timely communication and risk management. Foster collaboration across teams, mentor peers, and uphold safety and quality standards whi...
2 weeks ago
Senior Tax Associate, Indirect Sales and Use
$85K - $100K *
Join a team that's dedicated to delivering exceptional indirect tax solutions. You'll manage compliance, conduct research, and collaborate with clients across multiple jurisdictions, enhancing their t...
1 week ago
Sr. Manager Talent Management and HRBPs
$125K - $145K *
Lead the charge in shaping talent management strategies while guiding HR Business Partners. Drive performance management, succession planning, and employee engagement initiatives to enhance organizati...
Yesterday
$87K - $100K *
Champion the finance operations for Taft-Hartley benefit funds, overseeing reporting, audits, and team development. Drive process improvements and ensure accuracy in financial reporting while liaising...
1 week ago
$199K - $285K *
Empower enterprise transformation by leading strategic initiatives and engaging with C-level executives. Collaborate cross-functionally to drive revenue and deliver impactful workshops that showcase i...
2 weeks ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.