Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$100K - $120K *
Join a dynamic team as you guide school districts in crafting effective solution strategies. Collaborate with sales and product teams to enhance educational outcomes through tailored technology soluti...
4 days ago
$88K - $105K *
Manage complex projects by leading multidisciplinary teams, ensuring timely deliverables, budgeting, and client engagement throughout the entirety of the project lifecycle while utilizing sustainable...
Reposted 1 week ago
Regional Medical Science Director (South)
$200K - $235K *
Unlock potential by driving scientific excellence as a strategic partner, educating healthcare professionals on Immuno-Oncology and fostering relationships that support cancer therapeutic initiatives...
Reposted 2 weeks ago
$120K - $150K *
Empower strategic partnerships to enhance product distribution and revenue. Collaborate with cross-functional teams to drive integration, manage agreements, and optimize partner relationships for grow...
3 weeks ago
Licensed Psychologist, Peer Reviewer - ABA Services - Remote
$91K - $163K *
Join a team that's dedicated to evaluating ABA treatment requests, applying clinical criteria, and collaborating with providers to ensure quality care. Leverage your expertise in a fast-paced environm...
2 weeks ago
Senior Account Manager, SLED-WA
$110K - $130K *
Empower public-sector organizations by driving technology solutions in Washington. Develop new relationships, expand accounts, and collaborate with teams to enhance government operations and education...
2 weeks ago
$72K - $100K *
Join our dynamic team as a Sr. Credit Analyst, owning the underwriting cycle from application review to decision-making. Leverage your analytical skills to enhance credit processes and contribute to a...
2 weeks ago
$65K - $108K *
Lead the charge in expanding distribution relationships and driving sales growth. Collaborate with key stakeholders to identify opportunities, enhance client engagement, and optimize strategic initiat...
Yesterday
Claims Specialist III - Excess & Surplus
$103K - $136K *
Optimize complex casualty claims management by investigating, negotiating, and resolving high-severity cases while ensuring compliance and effective communication with stakeholders to achieve favorabl...
6 days ago
Sr. Underwriter - Life Underwriting - Remote
$87K - $146K *
Partner with us to deliver thoughtful underwriting decisions and build trusted relationships. Leverage your expertise to enhance processes and contribute to a collaborative environment that drives inn...
2 weeks ago
Senior Site Contracts Manager (Sponsor Dedicated /Remote - US Based)
$79K - $139K *
Join a team that's dedicated to driving excellence in clinical trial contracts. As a Senior Site Contracts Manager, you'll negotiate and manage site budgets and agreements, collaborating with key stak...
1 week ago
Securities Operations Associate Manager
$80K - $95K *
Lead a dynamic team in securities operations, ensuring compliance and quality in check processing. Collaborate with various departments to enhance processes, manage escalations, and drive talent devel...
6 days ago
$85K - $100K *
Join a dynamic team as you drive data integrity and enhance client reporting through Addepar. Leverage your analytical skills and operations experience to support private investment processes and coll...
1 week ago
$200K - $400K *
Unlock your potential as a strategic leader, driving enterprise account growth and fostering deep client relationships. Collaborate cross-functionally to align commercial strategies with client object...
Reposted yesterday
Executive Director, Clinical Development
$340K - $370K *
Elevate your career by leading critical clinical programs, ensuring high-quality execution from trial design to regulatory interactions. Collaborate cross-functionally to advance pivotal studies in a...
Reposted today
(Senior) Relationship Manager- Western Region (WER)
$72K - $110K *
Lead the charge in managing a diverse portfolio of network organizations, fostering relationships, and implementing strategic capacity-building initiatives to enhance organizational performance and su...
1 week ago
Manager, Client Delivery - Insurance Discovery
$65K - $116K *
Engage with clients to ensure seamless delivery of Insurance Discovery services, managing relationships and expectations while coordinating with internal teams for successful implementation and ongoin...
Today
$79K - $103K *
Optimize supplier relationships and purchasing strategies to enhance operational efficiency. Lead complex negotiations, manage supplier performance, and ensure compliance while supporting new product...
6 days ago
$100K - $120K *
Pioneer innovative eDiscovery solutions by managing complex projects, collaborating with legal teams, and mentoring staff. Ensure quality deliverables while exceeding client expectations through exper...
2 weeks ago
Regulatory and Legal Operations Manager
$110K - $130K *
Optimize regulatory compliance and legal operations in healthcare. Collaborate with cross-functional teams to ensure adherence to industry standards while driving efficiency and effectiveness in legal...
6 days ago
$74K - $124K *
Elevate compensation strategies by transforming complex data into actionable insights. Collaborate with stakeholders to manage compensation programs, analyze trends, and recommend solutions that ensur...
1 week ago
Senior Lead Electrical Engineer
$148K - $200K *
Champion innovative electrical design for mission-critical facilities. Lead complex projects, mentor teams, and enhance efficiency through technology. Collaborate with stakeholders to ensure project s...
2 weeks ago
Advising Specialist II, Wealth Management Advice and Solutions
$87K - $105K *
Shape the future of financial planning as a subject matter expert, implementing standardized reviews to ensure quality, guiding teams to enhance service delivery, and driving policy improvements throu...
Reposted 1 week ago
Senior SaaS Client Relationship Manager
$63K - $108K *
Lead enterprise accounts with 75+ locations, driving SaaS adoption and maximizing business value. Utilize industry expertise to resolve challenges, enhance client relationships, and support strategic...
5 days ago
Senior Director - BDM - Life Insurance & Annuities
$170K - $200K *
Join us to drive client relationships and business growth, managing complex accounts while ensuring delivery excellence. Collaborate with stakeholders to create strategic account plans and lead new bu...
1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.