Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Senior Customer Success Manager
$110K - $130K *
Unlock potential by driving customer success through strategic relationships and exceptional service. Collaborate cross-functionally to enhance product adoption and ensure client satisfaction, ultimat...
Today
Senior Customer Success Manager
$110K - $130K *
Join a team that's dedicated to enhancing customer satisfaction by driving product adoption and delivering exceptional service. You'll build strong relationships with clients, ensuring they achieve th...
4 days ago
Commercial Property General Adjuster
$80K - $95K *
Unlock your potential as a Commercial Property General Adjuster, where you'll investigate and resolve complex claims, negotiate settlements, and mentor junior staff in a dynamic environment. Embrace t...
4 weeks ago
Senior Preconstruction Manager
$100K - $120K *
Elevate project success by leading preconstruction activities, including estimating, scheduling, and planning. Collaborate with clients and teams to ensure alignment with project goals while managing...
6 days ago
$100K - $300K *
Lead complex analytical initiatives by developing data solutions and dashboards that drive business insights. Collaborate with stakeholders to translate requirements into scalable analytical framework...
1 week ago
Manager Claims Client Liaison - Remote
$110K - $130K *
Lead the charge in enhancing claims support and customer relationships by managing a high-performing team, ensuring service excellence, and driving operational improvements across Workforce Benefits p...
6 days ago
$119K - $165K *
Join our team as a Senior Recruiter, driving full-cycle recruiting for Sales, Customer Success, and Partnerships. Collaborate with leaders to enhance our hiring processes and ensure a positive candida...
1 week ago
Project Manager, Client Services (Fri-Mon ET or CT 10 hour days)
$90K - $110K *
Optimize eDiscovery project management by driving workflows, ensuring quality, and meeting litigation requests. Collaborate with teams to enhance processes and maintain stakeholder communication for s...
2 weeks ago
Senior Manager, Third Party Data Governance
$120K - $145K *
Shape the future of data governance by leading a team to manage third-party data compliance, ensuring operational excellence and regulatory adherence while fostering collaboration across business unit...
5 days ago
Senior Human Resources Generalist
$84K - $107K *
Support our team as a Senior Human Resources Generalist, overseeing employee relations, benefits, and recruitment in a factory setting. Collaborate on community outreach and wellness programs while en...
1 week ago
Senior Recruiter, Executive & Sales
$100K - $125K *
Champion strategic recruitment initiatives by partnering with executives to build a robust talent pipeline, ensuring alignment with evolving business needs and driving effective sourcing strategies fo...
3 days ago
$100K - $120K *
Lead the charge in driving sales growth and customer engagement by managing key accounts and project strategies. Collaborate with cross-functional teams to enhance product positioning and deliver exce...
3 days ago
Senior Vice President, Consumer Panel & Behavior Products| Level 22| US: Remote
$325K - $343K *
Lead the charge in shaping the product vision and strategy for consumer panel and behavioral measurement solutions, driving growth through innovative AI-native practices and client collaboration...
6 days ago
Senior Planner- Private Wealth
$110K - $130K *
Champion client success by leading cross-functional teams to deliver personalized financial planning. Leverage expertise in tax, estate, and investment management to craft tailored solutions for High...
Reposted 2 weeks ago
$146K - $229K *
Drive the AI roadmap and deliver secure, scalable solutions that enhance decision-making and streamline workflows. Lead teams from experimentation to production, ensuring measurable business value and...
Today
Financial Planning and Investments Oversight Officer
$110K - $130K *
Transform your career by providing expert oversight in fiduciary financial planning and investment management. Collaborate with a team to ensure alignment with client objectives and firm standards whi...
2 weeks ago
$75K - $110K *
Shape the financial landscape by driving month-end close processes, ensuring general ledger accuracy, and enhancing accounting practices in a dynamic, multi-revenue stream environment. Collaborate to...
3 weeks ago
Functional Specialist/Advisor - TS/SCI
$74K - $130K *
Elevate operational efficiency by providing project coordination and logistical support. Collaborate with stakeholders to enhance business continuity, risk management, and process analysis while devel...
3 days ago
Functional Specialist/Advisor - TS/SCI
$74K - $130K *
Shape operational excellence by providing project coordination, logistical support, and business continuity planning. Collaborate with stakeholders to enhance mission assurance and streamline processe...
6 days ago
$126K - $162K *
Drive project success by leading design and construction phases, managing teams, and ensuring client satisfaction in commercial and mission-critical environments. Collaborate with stakeholders to deli...
2 weeks ago
$223K - $255K *
Shape the future of patient access through science and evidence. In this field-based role, engage with national and regional payers, providing medical leadership and insights to inform access decision...
Today
Sr. Capture Manager (Enterprise Pursuits)
$120K - $145K *
Champion strategic growth by leading major enterprise pursuits, fostering collaboration, and driving consultative sales processes. Leverage your expertise to develop winning strategies and ensure oper...
5 days ago
$195K - $244K *
Unlock your potential as a Global Regulatory Leader, driving regulatory strategy and submissions for CNS projects. Collaborate with cross-functional teams, mentor junior staff, and ensure compliance w...
4 weeks ago
Senior Director, Oncology Clinical Educators
$197K - $246K *
Lead the charge in building strategic relationships with national payers, ensuring access and reimbursement for products. Drive initiatives that enhance patient affordability while collaborating with...
2 weeks ago
$80K - $95K *
Champion exceptional research outcomes by guiding clients through complex projects. Leverage your expertise in methodology and analysis to deliver actionable insights, while collaborating with cross-f...
2 weeks ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.