Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$125K - $150K *
Shape compliance excellence by overseeing post-closing functions, managing risks, and driving continuous improvement. Collaborate with stakeholders to ensure adherence to regulations and enhance the C...
3 weeks ago
Manager, Political Affairs ( Remote )
$89K - $134K *
Shape political engagement strategies by managing PAC operations, ensuring compliance, and providing analysis to enhance alignment with public policy priorities. Collaborate across departments to driv...
1 week ago
$110K - $130K *
Manage the full sales cycle to open new mid-market and enterprise accounts, develop cross-sell opportunities, and grow customer relationships through high-value cybersecurity services, ensuring commer...
Reposted 1 week ago
Accounting Team Manager (Not For Profit) - Multi-Client Exp. Required
$80K - $95K *
Advance your career by leading multi-team oversight and management in accounting operations across diverse industries. Utilize your expertise in compliance, software integration, and project managemen...
1 week ago
$110K - $130K *
Lead financial operations and strategic insights to enhance scalability and integrity. Oversee accounting functions, reporting, and compliance while partnering with leadership to drive growth and opti...
1 week ago
$164K - $305K *
Lead the charge in developing strategic relationships with C-suite executives to drive growth, retention, and value realization across complex health systems, ensuring integrated solutions and measura...
1 week ago
$85K - $95K *
Join a team that's dedicated to financial analysis and strategic support, driving insights for monthly close processes and cross-functional collaboration. This role emphasizes independent analysis and...
Today
Director, Medical Science Liaisons-Oncology
$221K - $368K *
Join a team that's dedicated to advancing oncology through leadership and innovation. Lead and develop a high-performing team of MSLs while driving strategic medical initiatives and fostering cross-fu...
1 week ago
$150K - $180K *
Drive strategic initiatives and operational excellence by partnering with leadership to translate priorities into actionable plans, fostering alignment, and enhancing decision-making across U.S. & Can...
Reposted 4 days ago
Captive Business Development Manager - River Oak Risk
$80K - $95K *
Drive new business generation in captive management solutions, focusing on multifamily risk and large P&C alternatives. Build relationships with brokers and multifamily owners while managing the full...
5 days ago
Senior MSSP Revenue Assurance Analyst
$132K - $182K *
Unlock the potential of MSSP revenue operations by leading strategy and execution. Drive partner onboarding, deal governance, and revenue acceleration while collaborating across teams to enhance opera...
3 weeks ago
Shareholder Services Lead - Hybrid
$118K - $196K *
Transform employee equity and shareholder services by leading stock plan operations, ensuring compliance and accuracy while collaborating with cross-functional teams to enhance processes and support s...
5 days ago
Senior Clinical Scientist - Oncology - Home Based
$110K - $130K *
Transform your career with a pivotal role in clinical research, leading oncology studies and collaborating with cross-functional teams to ensure scientific excellence and regulatory compliance while m...
1 week ago
Senior Tax Manager - US Controversy
$137K - $229K *
Join a dynamic tax team to manage IRS audits, drive controversy strategies, and enhance audit readiness. Collaborate with stakeholders to resolve complex tax matters in a fast-paced corporate environm...
4 days ago
Kranz EG Senior Accountant Consultant
$90K - $110K *
Join a team that's dedicated to delivering exceptional financial services. This role involves managing accounts payable, payroll, cash management, and month-end reconciliations while collaborating clo...
4 weeks ago
$180K - $235K *
Drive growth by leveraging your consultative sales expertise to engage higher education leaders, aligning their needs with innovative research solutions while managing client relationships and achievi...
2 weeks ago
Senior AI Engineer (CCC Casualty / Claims Intelligence)
$180K - $225K *
Transform the future of auto claims by designing AI agents that enhance decision-making and streamline processes. Join a dynamic team to build innovative solutions that improve efficiency and accuracy...
Today
Senior Consultant, Functional Transformation - ServiceNow HRSD
$116K - $229K *
Deliver impactful ServiceNow HRSD solutions by leading implementations, optimizing processes, and collaborating with cross-functional teams to enhance HR service delivery and client satisfaction...
Today
$93K - $116K *
Empower integrated marketing campaigns with a focus on account-based marketing. Collaborate with Sales to prioritize accounts, align messaging, and drive pipeline growth while managing multi-channel c...
1 week ago
Senior Consultant, Functional Transformation - ServiceNow HRSD
$116K - $229K *
Drive ServiceNow HR Service Delivery implementations, optimizing design, build, and deployment. Collaborate with teams to gather requirements, document processes, and ensure project success while enha...
Today
$100K - $110K *
Join a team that's dedicated to enhancing compliance and operational integrity through thorough audits and evaluations, ensuring adherence to regulations while fostering a culture of continuous improv...
4 weeks ago
$135K - $160K *
Empower strategic growth by developing and executing multi-year partner strategies. Collaborate with sales and executive teams to enhance alliances, drive revenue, and foster innovation across North A...
2 weeks ago
Director, Professional Services - Cybersecurity
$160K - $175K *
Transform cybersecurity professional services by leading delivery execution, ensuring quality, and developing talent. Collaborate with cross-functional teams to enhance service capabilities and drive...
2 weeks ago
$95K - $115K *
Champion client success by managing complex engagements in healthcare solutions. Leverage your expertise to enhance Quality/HEDIS, CMS Stars, and Risk Adjustment outcomes, ensuring effective adoption...
Today
Client Success Manager - Law Firms
$85K - $95K *
Lead the charge in client engagement and lifecycle management, driving retention and organic growth within legal accounts. Build relationships, identify cross-sell opportunities, and ensure high clien...
2 weeks ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.