Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Senior Consultant - Grants Lifecyle Process Improvement
$98K - $163K *
Optimize federal grants management operations by assessing processes, identifying inefficiencies, and delivering actionable recommendations. Collaborate with stakeholders to enhance program outcomes a...
3 weeks ago
Director, Partnership Tax- National Tax
$231K - $334K *
Elevate your career by leading partnership tax initiatives, providing expert guidance on complex federal tax matters, and collaborating with professionals to develop tailored solutions that drive clie...
2 weeks ago
RPA Senior Manager - Intelligent Automation
$178K - $338K *
Inspire innovation in healthcare by architecting RPA solutions that streamline revenue cycle processes while providing project management and technical expertise to drive client success and team colla...
Reposted today
Managing Director, Go-to-Market Value Creation
$210K - $250K *
Drive portfolio value creation through strategy execution, leveraging your extensive experience in revenue growth and go-to-market capabilities to lead engagements and mentor GTM teams across technolo...
Reposted 2 weeks ago
$110K - $130K *
Transform claims management by leading strategic initiatives, overseeing operations, and driving continuous improvement across a diverse portfolio, ensuring optimal outcomes and compliance while colla...
1 week ago
Manager, Life Underwriting (Remote)
$94K - $155K *
Join a team that's dedicated to enhancing underwriting excellence through analytics and innovation. Lead a skilled group of underwriters, manage complex cases, and collaborate across teams to improve...
3 weeks ago
Senior Regulatory Strategist, Advertising & Promotion (work from home)
$120K - $145K *
Empower regulatory excellence by guiding cross-functional teams in compliance and strategy. Leverage deep FDA knowledge to influence promotional materials and ensure adherence to evolving regulations...
2 weeks ago
Program Director, Professional Services
$180K - $200K *
Accelerate progress at regional Professional Services by leading teams, driving growth and quality in consulting engagements while fostering strategic partnerships and developing innovative service of...
Reposted 3 weeks ago
$90K - $110K *
Optimize patient care by leading the rehabilitation department, ensuring compliance and financial performance while fostering teamwork and excellence in service delivery across multiple sites...
6 days ago
Product Director, Institutional Solutions
$126K - $168K *
Lead the charge in shaping and executing product strategy for B2B learning solutions, driving innovation and market impact while collaborating with cross-functional teams to deliver high-quality produ...
2 weeks ago
$110K - $130K *
Champion financial integrity and compliance by leading accounting operations, overseeing reporting, and enhancing processes in a dynamic real estate development environment focused on affordable housi...
1 week ago
$110K - $130K *
Transform your legal career by engaging in complex medical malpractice litigation. Collaborate with a dynamic team, develop defense strategies, and represent clients in court while enjoying flexible w...
1 month ago
$110K - $130K *
Drive excellence in audit management by leading teams, overseeing engagements, and enhancing client relationships. Foster a culture of development while ensuring compliance and delivering high-quality...
2 weeks ago
$100K - $120K *
Lead the charge in managing audit engagements, ensuring quality and efficiency while developing a skilled team. Drive client relationships and oversee all phases of assurance services to deliver excep...
2 weeks ago
Account Executive, Risk Management
$100K - $120K *
Unlock client success by managing complex Risk Management accounts, coordinating teams, and driving service delivery. Collaborate with clients to ensure expectations are met and explore opportunities...
3 weeks ago
$80K - $95K *
Support project management by coordinating study documentation, mentoring team members, and ensuring compliance. Leverage expertise in clinical research to enhance study start-up and execution, while...
2 weeks ago
$90K - $115K *
Join a team that's dedicated to ensuring financial accuracy and integrity. In this role, you'll manage month-end close processes, support audits, and enhance accounting practices while mentoring junio...
2 weeks ago
Underwriting Director, Excess Casualty
$82K - $180K *
Transform underwriting strategies by managing excess casualty business, fostering relationships with wholesale partners, and ensuring profitable outcomes while adhering to company guidelines and marke...
2 weeks ago
Strategic Account Executive, West
$330K - $350K *
Unlock potential by driving strategic expansion within Global 2000 accounts. Manage complex SaaS deals, collaborate with cross-functional teams, and deliver measurable business outcomes through innova...
2 weeks ago
$80K - $95K *
Lead a dynamic team in managing compliance and risk within the mortgage sector. Ensure timely review of disposition requests and foster adherence to ECOA, FCRA, and adverse action regulations while dr...
Reposted 3 weeks ago
$95K - $115K *
Optimize patient access workflows by aligning registration with revenue cycle needs. Collaborate with stakeholders to enhance eligibility processes and improve patient estimates, while mentoring IS st...
1 week ago
$117K - $173K *
Transform the Corporate Trust Transfer Agency by managing multiple processing units, ensuring high-quality service and compliance. Guide teams, monitor controls, and develop strategic plans to leverag...
3 weeks ago
$117K - $173K *
Elevate operational excellence by managing multiple securities processing units, guiding teams to ensure high-quality service delivery while adhering to regulations and industry standards. Drive strat...
3 weeks ago
$117K - $173K *
Lead the management of multiple securities processing units, ensuring high-quality service and compliance. Collaborate with teams to develop strategic plans, enhance operational efficiency, and suppor...
3 weeks ago
Deputy PM - Construction Manager, Senior
$125K - $225K *
Oversee complex industrial construction projects, ensuring safety, quality, and timely completion. Lead multidisciplinary teams, manage contractor performance, and coordinate with stakeholders to achi...
1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.