Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$162K - $203K *
Unlock your potential by leading tax controversy and governance initiatives. Collaborate across teams to shape sustainable tax strategies while managing federal audits and enhancing organizational cap...
1 week ago
$145K - $175K *
Unlock potential by serving as a strategic advisor to enterprise clients, guiding them through complex stakeholder environments with predictive intelligence and data-driven insights to drive impactful...
2 weeks ago
Senior Advisor, Clinical Science (remote)
$168K - $283K *
Lead the charge in advancing early-stage clinical trials for innovative Orexin-targeted therapies. Collaborate cross-functionally to shape scientific strategy, drive execution, and ensure high-quality...
Reposted today
Senior Advisor, Clinical Science (remote)
$153K - $268K *
Transform clinical science in late-stage trials for innovative sleep/wake therapies. Collaborate cross-functionally to ensure compliance, drive recruitment, and deliver high-quality results while shap...
Reposted today
$85K - $100K *
Lead the charge in generating sales through provided leads, utilizing your strong communication skills to connect with clients and drive revenue growth. Enjoy comprehensive training and advancement op...
Yesterday
IP and Technology Transactions Attorney
$170K - $200K *
Drive impactful legal strategies by leveraging your expertise in intellectual property and technology transactions. Join a dynamic team to negotiate contracts and advise on legal matters, contributing...
3 weeks ago
Managing Director - AIE & Amazon Commerce Connections Lead
$125K - $295K *
Shape the future of Amazon Commerce by leading AI-enabled solutions that transform complex data into actionable insights, driving business growth and innovation across multiple clients and sectors...
Yesterday
Director HR Business Partner - Remote
$155K - $259K *
Champion organizational success by leading HR strategies, guiding senior leaders, and fostering an inclusive workplace. Leverage HR expertise to enhance talent management and drive business performanc...
6 days ago
$110K - $130K *
Discover a pivotal role as a Pharmacy Actuary, bridging pharmacy strategy and actuarial insights. Collaborate with cross-functional teams to enhance financial projections and support strategic pricing...
5 days ago
$90K - $120K *
Optimize client financial systems by implementing tailored processes, managing teams, and providing strategic support to dynamic startups. Engage with diverse clients, ensuring effective communication...
Reposted 2 days ago
$90K - $110K *
Empower nursing excellence by leading clinical operations and quality initiatives. Drive resident outcomes and foster a collaborative culture while ensuring compliance and staff development in a dynam...
Yesterday
$132K - $199K *
Lead the charge in driving Professional Services sales and client success within the US Public Sector, collaborating across teams to maximize revenue, enhance client relationships, and ensure successf...
6 days ago
$125K - $145K *
Drive product strategy and modernization for merchant onboarding solutions, collaborating with cross-functional teams to enhance risk management capabilities and ensure market-leading standards in a d...
Reposted 1 week ago
Vice President, Executive Planning Consultant - Lakes Region
$96K - $210K *
Shape the future of financial planning by serving as a trusted advisor to senior executives, providing tailored investment strategies and comprehensive financial guidance to enhance their financial we...
2 days ago
$100K - $120K *
Elevate customer relationships by managing and growing strategic national accounts. Focus on retention, upselling, and cross-selling within the Collision and Mechanical sectors while leveraging SaaS s...
2 weeks ago
Senior People Business Partner (Remote USA)
$110K - $130K *
Partner with us to drive high-performing teams and align HR strategies with business goals. Collaborate with leaders and employees to foster an inclusive culture, enhance leadership capabilities, and...
5 days ago
$110K - $130K *
Lead the charge in managing complex projects within our EPMO, ensuring timely delivery and alignment with strategic goals while fostering collaboration across diverse teams and stakeholders...
Reposted 2 weeks ago
$80K - $95K *
Lead the implementation of safety programs across multiple wind and solar project sites, ensuring compliance and promoting a safe work environment for all team members and contractors. Collaborate wit...
Reposted 1 week ago
Claim Specialist Commercial General Liability - Major Case Unit
$107K - $161K *
Advance your career by managing complex bodily injury claims in a dynamic environment. Utilize your expertise in primary and excess coverages to drive high-quality outcomes while collaborating with le...
4 days ago
Senior Consultant, Business SOX IA
$73K - $105K *
Join a team that's dedicated to enhancing internal audit processes and SOX compliance. Leverage your expertise in software and manufacturing environments to lead engagements, mentor staff, and drive i...
2 weeks ago
$85K - $105K *
Optimize regulatory compliance processes for a multi-state transportation network. Collaborate cross-functionally to ensure operational readiness and manage ongoing compliance across diverse markets...
1 week ago
$104K - $145K *
Join us to lead a dynamic team managing consumer complaints in lending operations. You'll enhance complaint resolution processes, ensure regulatory compliance, and drive continuous improvement, all wh...
3 weeks ago
Account Manager, Consulting & Professional Services
$100K - $120K *
Deliver exceptional client engagement by managing relationships and driving growth within a diverse portfolio. Collaborate with teams to maximize retention and uncover new opportunities, ensuring clie...
4 weeks ago
Senior Manager, Clinical Operations Programs
$160K - $190K *
Join a team that's driving excellence in clinical operations, leading global studies and ensuring regulatory compliance. Utilize your project management expertise to enhance efficiency and maintain hi...
Reposted 1 week ago
$80K - $95K *
Transform your career by leading a dynamic survey team, fostering client relationships, and delivering impactful projects that enhance community development while ensuring quality and compliance throu...
6 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.