Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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1,000+

Senior Counsel Jobs in Missouri

Sort By: Relevance

$120K - $145K *

Transform regulatory strategies for rare disease and cardio-pulmonary drug-device programs. Collaborate with cross-functional teams to ensure compliance and drive successful submissions globally, supp...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $135K *

Join a dynamic team to oversee tax engagements, manage client relationships, and mentor junior staff. Utilize your expertise in tax planning and compliance while contributing to various consulting pro...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$95K - $115K *

Empower our team by managing complex medical professional liability claims. Utilize your expertise to shape strategies, coordinate resources, and influence outcomes in a collaborative environment whil...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $140K *

Optimize client relationships by ensuring seamless communication and operational excellence. Collaborate across teams to drive client success, manage deliverables, and enhance platform utilization whi...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$300K - $325K *

Drive your career with a strategic leadership role focused on enhancing marketing initiatives, optimizing client engagement, and achieving commercial growth across diverse financial services sectors...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Finance & Insurance

$75K - $110K *

Elevate our Internal Audit function by conducting comprehensive audits, evaluating controls, and ensuring compliance. Collaborate across teams to enhance processes and contribute to effective governan...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$122K *

Elevate your career by managing global projects in Neuroscience, ensuring compliance, budget adherence, and successful collaboration across cross-functional teams to drive milestone achievement and en...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$315K - $350K *

Lead the charge in transforming enterprise actuarial capabilities, providing strategic oversight across modeling, valuation, and governance. Collaborate with executives to enhance decision-making and...

United StatesRemote

5 days ago

  •   11 - 15 years exp.  •   Finance & Insurance

$210K - $250K *

Champion the evolution of HR Business Partnering globally, driving strategic workforce initiatives and organizational effectiveness while partnering with senior leaders to enhance talent and leadershi...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $100K *

Unlock potential by leveraging your claims expertise to analyze and resolve complex workers' compensation claims, ensuring timely adjudication and exceptional client service in a dynamic, supportive e...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $100K *

Drive new client acquisition and expansion by building strong relationships, identifying opportunities, and leveraging consultative sales techniques to increase revenue through corporate gifting solut...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$110K - $130K *

Lead transformative Workday implementations, managing client relationships and project lifecycles. Drive innovation and strategic growth while ensuring exceptional customer satisfaction and effective...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$100K - $120K *

Grow client relationships by managing and expanding large renewal accounts. Collaborate with cross-functional teams to drive revenue retention while maximizing client satisfaction and implementing str...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $95K *

Lead the charge in driving customer success for mid-market accounts, ensuring adoption and renewals while identifying growth opportunities. Collaborate cross-functionally to enhance customer experienc...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$88K - $105K *

Support the Legal team by managing operations, driving technology adoption, and optimizing processes. Collaborate with stakeholders to enhance efficiency and implement improvements in legal operations...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$127K - $223K *

Transform the way we communicate life insurance through compelling copy that captures attention and drives action. Collaborate with teams to create impactful Direct Mail and social media content that...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Finance & Insurance

$225K - $295K *

Accelerate progress at the forefront of contract lifecycle management by driving innovation and strategic solutions. Collaborate with sales teams to enhance customer satisfaction and market leadership...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$90K - $120K *

Advance strategic initiatives by collaborating across teams to launch innovative data tools and insurance programs. Drive project management efforts and contribute to executive presentations that shap...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$160K - $190K *

Drive strategic growth by managing key Pharma and Biotech accounts, engaging C-suite executives, and leading expansion sales processes. Collaborate cross-functionally to enhance client experiences and...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$70K - $110K *

Join a team that's dedicated to supporting disaster recovery efforts. Collaborate with leadership and clients to navigate complex recovery operations, ensuring effective management of multi-billion do...

RemoteRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Business Services

$94K - $179K *

Lead the charge in managing complex projects from inception to completion, ensuring timely delivery and stakeholder satisfaction while guiding cross-functional teams through the project lifecycle...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$250K - $350K *

Elevate your career by leading strategic M&A initiatives, driving business development, and mentoring a dynamic team. This role demands a metrics-driven mindset to deliver measurable results while man...

1 week ago

  •   8 - 10 years exp.  •   Legal & Accounting

$107K - $134K *

Drive innovative actuarial pricing solutions by leading complex projects, enhancing filing processes, and collaborating cross-functionally to align technical insights with strategic goals in a dynamic...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Enterprise Technology

$78K - $206K *

Unlock potential by leading clinical performance improvement projects for Medicare Provider Collaboration groups. Collaborate with teams to enhance population health outcomes, focusing on Stars qualit...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $140K *

Reimagine client success by managing relationships and ensuring seamless communication across teams. Drive operational excellence and enhance client satisfaction through proactive updates, coordinatio...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.