Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Sr Financial Accounting Specialist
$76K - $142K *
Lead advanced accounting functions, ensuring compliance with GAAP and SAP. Prepare complex financial reports and analyses while collaborating with auditors. Drive financial accuracy and support manage...
2 weeks ago
$125K - $150K *
Lead the charge in transforming public sector consulting by guiding organizations through digital transformation and ERP implementations, while managing high-impact teams and fostering client relation...
3 weeks ago
Clinical Trial Liaison (Oncology)
$100K - $120K *
Accelerate progress at clinical sites by enhancing patient recruitment strategies and supporting Oncology studies. Collaborate with teams to optimize enrollment processes and ensure effective communic...
6 days ago
Licensed Clinical Social Worker (Remote)
$78K - $92K *
Champion virtual behavioral health services by providing evidence-based counseling and developing treatment plans for military personnel, ensuring compliance with clinical standards and enhancing pati...
Today
Field Medical Director, Breast and Gynecological Cancers (Non-MD)
$176K - $294K *
Engage with healthcare professionals to deliver medical expertise and insights in oncology. Drive strategic initiatives, foster collaboration, and enhance patient-centric communications across diverse...
Reposted 1 week ago
$82K - $103K *
Champion sales initiatives by directing activities in a defined area, fostering relationships with key stakeholders, and executing innovative marketing strategies to drive growth in corporate retireme...
6 days ago
Corporate Counsel, Global Supply Chain
$134K - $231K *
Shape the future of global supply chain operations by providing strategic legal support, drafting contracts, and ensuring compliance with environmental and safety regulations. Collaborate across funct...
Reposted 1 week ago
$90K - $115K *
Unlock potential by leveraging your pharmacy expertise to drive client growth and retention. Collaborate with teams to provide consultative support and insights in pharmacy and medical policy, enhanci...
4 days ago
Senior Associate, Corporate Development
$135K - $165K *
Elevate your career by driving strategic acquisitions and value creation in a dynamic environment. Collaborate with cross-functional teams to identify targets, lead transactions, and build frameworks...
3 weeks ago
Director, Underwriting Strategy & Governance
$175K - $190K *
Join a team that's shaping underwriting excellence by mentoring talent, enhancing training, and driving strategic initiatives. Leverage your expertise to influence complex risk decisions and uphold go...
4 weeks ago
$100K - $120K *
Unlock potential by driving the operational excellence of a comprehensive Privacy Program. Collaborate across teams to enhance data protection, ensure compliance, and foster a culture of privacy that...
3 weeks ago
Managing Director, Investment Banking - Infrastructure Industry
$250K - $350K *
Join a dynamic team as you drive business development and oversee strategic transactions. Leverage your expertise in mergers and acquisitions while mentoring a talented execution team to achieve measu...
1 week ago
$100K - $125K *
Accelerate progress at our financial reporting function by leading compliance, ensuring accurate statements, and mentoring a skilled team. Drive technical accounting excellence and support executive d...
2 weeks ago
$155K - $185K *
Partner with us to lead high-impact projects in healthcare marketing, managing budgets and teams while ensuring creative excellence and strategic alignment. Drive client success through collaboration...
5 days ago
$89K - $134K *
Drive financial reporting excellence by managing complex transactions, coordinating teams, and ensuring compliance across functions. Leverage your expertise in accounting to enhance reporting quality...
Reposted 3 weeks ago
$88K - $113K *
Lead the management of complex, high-exposure liability claims, ensuring strategic direction and exceptional outcomes. Collaborate with stakeholders to develop effective resolution strategies while en...
3 weeks ago
Senior Budget and Financial Analyst (Remote)
$95K - $110K *
Lead financial management and analysis efforts to support strategic planning and budget execution for DHS initiatives, ensuring alignment with mission priorities and stakeholder requirements while dri...
5 days ago
Senior Cyber Security Consultant
$110K - $130K *
Shape the future of cybersecurity in higher education by delivering expert assessments, advisory services, and tailored remediation plans that empower institutions to enhance their security posture an...
Reposted 6 days ago
General Liability Claim Representative
$90K - $110K *
Champion the management of complex liability claims, ensuring thorough investigations, negotiations, and settlements. Collaborate with internal and external stakeholders to maintain high standards of...
1 week ago
Senior Director Compliance Monitoring & Surveillance
$144K - $210K *
Drive compliance excellence by leading a team focused on identifying and addressing control gaps and violations across financial services, ensuring adherence to regulatory standards while enhancing su...
Reposted 4 days ago
Compliance Counsel I - Investment Advisory
$95K - $115K *
Unlock potential by guiding compliance strategies in a dynamic investment advisory environment. Collaborate across various teams to enhance our compliance program, ensuring regulatory adherence and fo...
Reposted 3 weeks ago
$100K - $120K *
Empower recovery by providing expert neuropsychological assessments and interventions for patients with cognitive and behavioral challenges, collaborating with interdisciplinary teams to enhance rehab...
5 days ago
$100K - $120K *
Transform patient care by providing expert neuropsychological assessments and interventions. Collaborate with interdisciplinary teams to enhance rehabilitation outcomes for individuals recovering from...
6 days ago
$100K - $120K *
Transform lives as a Clinical Neuropsychologist, providing essential assessments and interventions for patients recovering from neurological conditions. Collaborate with interdisciplinary teams to enh...
6 days ago
Sr. HR Associate Relations Partner
$98K - $144K *
Champion the associate experience by advising leaders on performance management, compliance, and risk mitigation. Lead investigations, analyze trends, and develop training to enhance workplace culture...
2 weeks ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.