Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$100K *
Drive growth and strengthen relationships in Broker-Dealer and RIA channels. Consult with financial professionals on investment solutions, deliver market insights, and support business development ini...
2 weeks ago
Senior / Global Regulatory Labeling Strategist
$125K - $150K *
Champion global labeling strategy for innovative therapies, leading complex initiatives from development to post-approval. Collaborate with cross-functional teams to ensure compliance and high-quality...
2 weeks ago
Divisional Director, Advisor Acquisition
$120K - $150K *
Drive growth by recruiting experienced financial advisors and teams. Collaborate with field leadership to develop strategies, manage pipelines, and enhance market presence, ensuring successful onboard...
Yesterday
$58K - $105K *
Unlock your potential by managing the full contracting lifecycle, supporting critical agreements for Medicare Advantage and Commercial operations, while collaborating with diverse teams to enhance com...
1 week ago
$85K - $150K *
Empower strategic initiatives by leading cross-functional projects, conducting analysis, and delivering insights to executive leadership. Drive decision-making and enhance operational efficiency in a...
3 weeks ago
$85K - $150K *
Lead the charge in driving strategic initiatives by collaborating with executive leadership, managing complex projects, and delivering actionable insights to support high-priority decisions across the...
3 weeks ago
Sr. Staff Attorney (Regulatory)
$142K - $177K *
Lead legal initiatives by drafting documents, managing records, and providing counsel. Collaborate with executives to shape organizational direction while ensuring compliance and supporting continuous...
4 days ago
$95K - $115K *
Lead the charge in developing custom Duck Creek solutions, collaborating with clients and teams to deliver scalable, technical solutions while mentoring junior developers and driving project success...
2 weeks ago
Business Development Manager - Transactional Division
$110K - $120K *
Engage and drive regional growth for comprehensive due diligence services in the Midwest. Build strategic relationships with key stakeholders in commercial real estate, delivering actionable insights...
Reposted 1 week ago
$107K - $145K *
Drive growth by identifying and securing new business opportunities in risk management and medical education. Collaborate with teams to develop proposals, manage sales pipelines, and ensure alignment...
Reposted 6 days ago
Senior Advisor, Staff Well-Being and Workforce Resilience
$95K - $115K *
Transform staff well-being by leading strategic initiatives that enhance resilience and psychosocial support across diverse, high-stress environments, ensuring alignment with organizational priorities...
1 week ago
Principal Product Manager, GRC
$150K - $180K *
Drive product strategy and execution for a critical portfolio area, leading cross-functional teams to transform user insights into impactful software solutions while mentoring others and shaping platf...
1 week ago
$150K - $180K *
Empower your legal expertise by guiding a dynamic team through complex commercial and corporate matters, ensuring compliance and strategic support across North America while fostering a collaborative...
6 days ago
Lead Product Manager (Intellectual Property)
$125K - $150K *
Drive innovative product strategies and outcomes for a major AI platform, collaborating across teams and advocating for customer needs to enhance intellectual property workflows and product performanc...
Reposted 3 weeks ago
Lead Product Manager (Intellectual Property)
$120K - $145K *
Drive your career forward by leading product strategy for a unified AI platform, delivering innovative solutions, and collaborating with cross-functional teams to enhance customer experiences and achi...
Reposted 3 weeks ago
$160K - $180K *
Lead strategic health plan implementations and optimize client solutions. Drive cross-functional collaboration, manage complex projects, and enhance operational workflows to ensure successful launches...
6 days ago
Corporate Counsel/Senior Corporate Counsel
$140K - $160K *
Unlock potential by providing expert legal counsel on commercial agreements while collaborating with cross-functional teams to balance legal risk with business objectives in a dynamic and fast-paced e...
Reposted yesterday
GRC Engineer (Governance Risk and Compliance)
$115K - $140K *
Drive GRC initiatives by building and testing security controls, assessing risks, and automating evidence collection. Collaborate with teams to enhance compliance and support audits while ensuring eff...
1 week ago
Senior Servicing Officer (Institutional Capital Group)
$71K - $125K *
Transform complex loan servicing processes as a Senior Servicing Officer, managing a diverse portfolio in commercial real estate. Contribute to client partnerships and lead initiatives, while expandin...
Reposted 1 week ago
$160K - $200K *
Drive strategic leadership in underwriting, enhancing performance and scalability across lending channels. Collaborate with cross-functional teams to ensure sound credit decisions and regulatory compl...
1 week ago
Clinical Oversight Manager (COM) - USA
$110K - $130K *
Accelerate progress at the forefront of clinical research by ensuring effective oversight and management of clinical studies. Collaborate with teams to uphold quality standards and drive successful st...
6 days ago
Director, Debt Capital Markets
$150K - $180K *
Join a dynamic team to shape the future of multifamily debt strategy, ensuring asset protection and optimizing financing across acquisitions and refinances while driving investor returns through disci...
1 week ago
$190K - $305K *
Join a team that's shaping healthcare by providing legal guidance on regulatory matters, employee benefits, and AI initiatives. As a senior contributor, you'll lead complex reviews, manage risks, and...
Today
Compliance & Regulatory Counsel
$180K - $200K *
Manage compliance and regulatory functions for a global SaaS provider, advising on laws impacting enterprise clients. Collaborate cross-functionally to ensure timely compliance and develop best practi...
2 weeks ago
Sr. Clinical Project Research Manager - Oncology CRO Clinical
$110K - $130K *
Shape the future of clinical research by leading project teams to achieve milestones, ensuring compliance and operational excellence throughout all phases of study management while fostering collabora...
Today
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.