Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down

Sort By: Relevance

$179K - $249K *

Lead the charge in shaping and executing the Operational Risk program, collaborating with key teams to enhance risk management practices and reporting as the organization transitions to banking operat...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$83K - $140K *

Join a dynamic team to drive insurance product design and implementation. Collaborate cross-functionally to manage projects, ensuring alignment with strategic goals while facilitating effective busine...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$99K - $142K *

Shape the future of Medicaid by leading system modernization efforts, overseeing technology investments, and aligning strategies across diverse teams to enhance operational efficiency and governance i...

4 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$63K - $98K *

Champion public service by representing indigent clients in appellate cases. Engage in legal research, draft briefs, and present oral arguments while receiving mentorship from experienced attorneys in...

Yesterday

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$119K - $221K *

Advance your career by driving strategic sales initiatives within large enterprises. Collaborate with cross-functional teams to exceed sales quotas and develop innovative solutions that meet client ne...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$100K - $185K *

Unlock business growth by leading technical scoping, managing client relations, and guiding consultants. This hybrid role integrates project management with hands-on consulting to ensure accurate prop...

United StatesRemote

Reposted 1 month ago

  •   Less than 5 years exp.  •   Information Technology

$120K - $145K *

Optimize runtime authorization strategies across diverse segments, driving technical wins and enabling Sales Engineers. Leverage deep IAM and PAM expertise to deliver impactful solutions, ensuring com...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$66K - $110K *

Elevate your career by leading a dynamic team in retirement operations. Drive performance, enhance customer experiences, and implement process improvements while fostering a collaborative environment...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$75K - $90K *

Empower your career by joining a dedicated clinical team providing psychological services in long-term care. Enjoy professional autonomy, a flexible schedule, and robust support while making a meaning...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$160K - $190K *

Lead the charge in driving growth by managing a high-performing sales team, collaborating across functions, and executing strategic initiatives to enhance commercial success in the Hematology sector...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$272K - $340K *

Elevate your career by leading CMC Regulatory strategy and execution. Drive submissions, build a high-performing team, and engage with global health authorities to ensure compliance and success in dru...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$135K - $165K *

Tackle complex general liability claims by evaluating coverage issues, managing risks, and formulating resolution strategies. Collaborate with internal and external parties to ensure effective investi...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$85K - $161K *

Lead the charge in deploying and scaling enterprise AI solutions, ensuring secure and effective adoption. Collaborate with cross-functional teams to transform client needs into practical AI applicatio...

6 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$85K - $161K *

Unlock potential by deploying and supporting enterprise AI solutions, enhancing client readiness, and driving adoption through hands-on consulting and collaboration with cross-functional teams to ensu...

6 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$85K - $161K *

Shape the future of enterprise AI by deploying and supporting AI solutions, ensuring client readiness, and driving adoption. Collaborate with cross-functional teams to deliver innovative AI assistants...

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$85K - $161K *

Unlock potential by deploying and supporting enterprise AI solutions, enhancing client readiness, and driving adoption through hands-on development and consulting. Collaborate with cross-functional te...

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$79K - $98K *

Empower customer success by fostering relationships and driving value through strategic engagement and support. Collaborate cross-functionally to enhance customer satisfaction and retention while iden...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Lead feasibility strategy and execution for clinical studies, driving operational excellence and data-driven insights to optimize trial planning and enrollment across rare disease programs. Collaborat...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$191K - $305K *

Champion innovative healthcare solutions by leveraging clinical expertise to enhance value-based strategies, drive operational excellence, and foster strategic partnerships for improved member care an...

RemoteRemote

1 month ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Champion digital forensics projects by managing workflows, budgets, and client expectations. Collaborate with teams to enhance service delivery, ensuring high client satisfaction and adherence to dead...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Legal & Accounting

$110K - $130K *

Transform client security postures by delivering strategic risk assessments, developing governance frameworks, and leading cybersecurity initiatives. Collaborate with stakeholders to enhance complianc...

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$80K - $95K *

Manage and lead multiple teams of claims examiners, ensuring efficient operations and high-quality adjudication of bodily injury claims while driving continuous improvement and maintaining client rela...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$90K - $105K *

Collaborate with clients and teams to manage projects, expectations, and delivery, ensuring high standards and strategic growth in a fast-paced medical affairs environment. Leverage experience to iden...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$132K - $261K *

Join a team that's transforming workplace technology by leading digital employee experience initiatives, driving strategic recommendations, and enhancing productivity across enterprise environments...

2 weeks ago

  •   8 - 10 years exp.  •   Business Services

$75K - $90K *

Unlock potential by leading accounting services for diverse clients, managing month-end closings, and mentoring junior staff. Utilize your expertise to build client relationships and drive operational...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Legal & Accounting

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.